Complete Conference Coverage

AES 2015 Aptiom Monotherapy May Improve Quality of Life in Epilepsy

Aptiom Monotherapy May Improve Quality of Life in Epilepsy

Visits to the emergency department were also reduced.

AES 2015 Real-Time Seizure Detection Possible with Learning Algorithm

Real-Time Seizure Detection Possible with Learning Algorithm

Continuous analysis of EEG output helps the algorithm adapt to changes in brain activity.

AES 2015 Intractable Epilepsy Advances Brain Aging

Intractable Epilepsy Advances Brain Aging

Structural MRI revealed differences in white matter in people with intractable epilepsy compared to healthy controls.

AES 2015 Cannabidiol Effective for Reducing Seizures in Treatment-Resistant Epilepsy

Cannabidiol Effective for Reducing Seizures in Treatment-Resistant Epilepsy

A large, multi-center study found cannabidiol effective for the reduction of seizures

AES 2015 Novel Seizure Detection Device as Sensitive as Video EEG Review

Novel Seizure Detection Device as Sensitive as Video EEG Review

The Brain Sentinel device was as sensitive as vEEG review by an epileptologist for seizure detection.

AES 2015 Gene Mutations Associated with Sudden Cardiac Death Linked to SUDEP

Gene Mutations Associated with Sudden Cardiac Death Linked to SUDEP

Cardiac dysrhythmia may contribute to pathophysiology in a proportion of SUDEP cases.

AES 2015 Three Biosignals More Accurately Detect Seizures Than Heart Rate Alone

Three Biosignals More Accurately Detect Seizures Than Heart Rate Alone

Heart rate, arterial oxygenation, and electrodermal activity improved accuracy compared with heart rate alone.

AES 2015 Circadian Genes May Impact Pathogenesis of Pediatric Focal Epilepsy

Circadian Genes May Impact Pathogenesis of Pediatric Focal Epilepsy

These functional analyses suggest that the circadian pathway may be a promising target for therapeutic intervention.

AES 2015 Genetic Mutation Identification Expands Epilepsy Phenotypes

Genetic Mutation Identification Expands Epilepsy Phenotypes

Mutations were identified in 7 genes, including one for the first time.

AES 2015 Integration of Mental Health Screening May Prevent Suicide in Epilepsy

Integration of Mental Health Screening May Prevent Suicide in Epilepsy

Incorporating mental health screenings in epilepsy appointments may help prevent suicides.

AES 2015 Whole Exome Sequencing Effective for Epilepsy Diagnosis in Children

Whole Exome Sequencing Effective for Epilepsy Diagnosis in Children

WES identified a definite/likely diagnosis in 32% of patients and a possible diagnosis in 22% of patients, for an overall yield of 54%.

AES 2015 Brief Assessment Identifies Cognitive Issues in Children with Epilepsy

Brief Assessment Identifies Cognitive Issues in Children with Epilepsy

The 30-minute assessment may help identify those at highest risk of cognitive problems.

AES 2015 Temporal Lobe Epilepsy Via Hippocampal Sclerosis Affects Memory Function

Temporal Lobe Epilepsy Via Hippocampal Sclerosis Affects Memory Function

Impairment in recalling names, routes, stories, messages, and a space/time disorientation can adversely impact social adaptation.

AES 2015 Seizures Affect Long-Term Memory in Animal Study

Seizures Affect Long-Term Memory in Animal Study

Inhibiting the pathway upstream of mTOR at the level of PI3K signaling, a locus of significant molecular crosstalk in this pathway, restored the seizure-induced learning and memory deficits.

AES 2015 White Matter Abnormalities Linked to Cognitive Ability in Epilepsy

White Matter Abnormalities Linked to Cognitive Ability in Epilepsy

White matter integrity plays an important part in the neural signature of cognitive impairment in early onset epilepsy.

AES 2015 Simultaneous fMRI, Direct Electrical Stimulation Feasible in Epilepsy

Simultaneous fMRI, Direct Electrical Stimulation Feasible in Epilepsy

fMRI-DES could be used for full-brain volume evaluation of brain connectivity and help lead to the refinement of laser ablative procedures for epilepsy.

AES 2015 What to Expect at the 2015 American Epilepsy Society Annual Meeting

What to Expect at the 2015 American Epilepsy Society Annual Meeting

Ruben Kuzniecky, MD, outlines what to expect at this year's American Epilepsy Society Annual Meeting.