Cognitive Impairment

Cognitive Impairment in Multi-System Atrophy: Is It Time to Update Diagnostic Criteria?

Cognitive Impairment in Multi-System Atrophy: Is It Time to Update Diagnostic Criteria?

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Although evidence of cognitive impairment in MSA is admittedly more limited than in Parkinson disease, it is now substantial enough to address modification of diagnostic criteria to include the potential for cognitive impairment at any stage of the disease.

Subjective Cognitive Decline Associated With Tauopathy and Global β-Amyloid Burden

Subjective Cognitive Decline Associated With Tauopathy and Global β-Amyloid Burden

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Multiple biological factors may play a role when cognitive decline is observed in older health adults.

Parkinsonism Diagnosis Linked to Cognitive Deficits

Parkinsonism Diagnosis Linked to Cognitive Deficits

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Cognitive dysfunction may be a sign of prodromal Parkinson disease.

Atrial Fibrillation Associated With Cognitive Decline

Atrial Fibrillation Associated With Cognitive Decline

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Mechanisms including silent cerebral infarct, microemboli, microbleedings, and cerebral hypoperfusion may be responsible for the link between atrial fibrillation and cognitive decline.

Global Tau Burden Linked to Cognitive Decline

Global Tau Burden Linked to Cognitive Decline

SCD is associated with increased entorhinal cortical tau burden and β-amyloid burden in healthy older adults.

Nursing Home Use Increased With Cognitive Impairment

Nursing Home Use Increased With Cognitive Impairment

Individuals with prevalent dementia and any nursing home use had especially high 1-year mortality.

Vascular Dysfunction Compromises Cognition in Hyperparathyroidism

Vascular Dysfunction Compromises Cognition in Hyperparathyroidism

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Cognitive dysfunction may be the result of lower intracerebral vasomotor reactivity which is linked to PHPT.

Sleep-Disordered Breathing Predicts Risk for Cognitive Impairment in Elderly

Sleep-Disordered Breathing Predicts Risk for Cognitive Impairment in Elderly

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Older adults with sleep-disordered breathing have a 26% greater risk for developing cognitive impairment and a small risk for deteriorating executive function.

Evolocumab Has No Effect on Cognition in Patients Attaining Very Low Levels of LDL Cholesterol

Evolocumab Has No Effect on Cognition in Patients Attaining Very Low Levels of LDL Cholesterol

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Previous reports have suggested that statins or the low levels of LDL cholesterol they promote may have an adverse impact on cognition.

Lower Systolic Blood Pressure Targets May Benefit Cognition in Black Patients

Lower Systolic Blood Pressure Targets May Benefit Cognition in Black Patients

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Findings from this trial challenge current recommended systolic blood pressure targets for older adults.

No Association Between Cardiovascular Drugs and Cognitive Impairment

No Association Between Cardiovascular Drugs and Cognitive Impairment

There is no association between use of cardiovascular medication and cognitive impairment in older adults.

Visual Impairment Linked to Cognitive Dysfunction in Seniors

Visual Impairment Linked to Cognitive Dysfunction in Seniors

Visual dysfunction is associated with poor cognitive function in older adults.

Sleep-Disordered Breathing Associated With Cognitive Dysfunction

Sleep-Disordered Breathing Associated With Cognitive Dysfunction

Cognitive deficits can be caused by sleep-disordered breathing.

Cognitive Decline Related to Site Specific Mid-Life Adiposity

Cognitive Decline Related to Site Specific Mid-Life Adiposity

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An increase in weight ≥5% was associated with lower cognitive scores.

Algorithm Accurately Predicts Cognitive Decline in Parkinson's Disease

Algorithm Accurately Predicts Cognitive Decline in Parkinson's Disease

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Patients with the highest predictive scores faced a greater risk of developing cognitive impairment and dementia in the first 10 years after disease onset.

Cognitively Impaired Seniors Likely to be Taking Inappropriate Medications

Cognitively Impaired Seniors Likely to be Taking Inappropriate Medications

Many residents in nursing homes with cognitive impairments may be taking potentially inappropriate medications.

Light Therapy May Improve Depressive Symptoms in Cognitively Impaired Patients

Light Therapy May Improve Depressive Symptoms in Cognitively Impaired Patients

Light therapy has a moderate effect on behavioral disturbances and depression for people with cognitive impairment.

Youth Bipolar Disorder Does Not Impact Cognitive Function in Adulthood

Youth Bipolar Disorder Does Not Impact Cognitive Function in Adulthood

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Youth who have bipolar disorder are not affected by a decline in cognitive function into adulthood.

More Evidence Links Mediterranean Diet to Cognition

More Evidence Links Mediterranean Diet to Cognition

Improved cognitive function in older adults is being linked to the Mediterranean diet.

Several Factors May Predict Cognitive Decline in Parkinson's Disease

Several Factors May Predict Cognitive Decline in Parkinson's Disease

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Dopamine deficiency, decreases in cortical thickness and volume in certain areas of the brain was predictive of cognitive decline.

Degree of Amyloid Deposition Helps Predict Cognitive Decline

Degree of Amyloid Deposition Helps Predict Cognitive Decline

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The main differentiating factor was the presence of the APOE ε4 allele.

Pain Linked to Memory Decline, Dementia Risk

Pain Linked to Memory Decline, Dementia Risk

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Older adults with chronic pain have been found to have poorer memory and executive function than their younger counterparts.

Comparing Cognitive Dysfunction Assessments in Lupus

Comparing Cognitive Dysfunction Assessments in Lupus

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Cognitive dysfunction is 3 times higher in patients with systemic lupus erythematosus.

Intensive Lifestyle Intervention Holds No Benefit for Cognitive Impairment: Analysis

Intensive Lifestyle Intervention Holds No Benefit for Cognitive Impairment: Analysis

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An intensive lifestyle intervention including diet and exercise resulted in no improvements in cognitive impairment.

Serum Cytokine Levels May Correlate With Cognitive Dysfunction in Alzheimer's Disease

Serum Cytokine Levels May Correlate With Cognitive Dysfunction in Alzheimer's Disease

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Patients with Alzheimer's disease may have higher serum IL-6 levels than subjects with mild cognitive impairment and healthy controls.

In MS, Anxiety, Cognitive Fatigue May Affect Visual Memory

In MS, Anxiety, Cognitive Fatigue May Affect Visual Memory

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Cognitive fatigue and anxiety are common symptoms reported by patients with multiple sclerosis.

Aspirin Regimen Has No Benefit for Cognitive Decline

Aspirin Regimen Has No Benefit for Cognitive Decline

Chronic use of low-dose aspirin was not associated with onset of dementia or cognitive impairment, but was also not associated with significantly better global cognition.

Polypharmacy in Schizophrenia May Have Adverse Effect on Cognition

Polypharmacy in Schizophrenia May Have Adverse Effect on Cognition

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Patients with schizophrenia, schizoaffective disorder, and psychotic bipolar disorder were examined for anticholinergic burden.

New Gene Linked to Accelerated Decline in Alzheimer's

New Gene Linked to Accelerated Decline in Alzheimer's

Participants with the Met allele lost memory and cognitive skills more rapidly than those without the gene mutation.

Cognitive Skills Adversely Affected by Thyroid Dysfunction

Cognitive Skills Adversely Affected by Thyroid Dysfunction

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Patients with subclinical hypothyroidism scored worse on tests of processing speed than patients with normal thyroid function.

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