Although evidence of cognitive impairment in MSA is admittedly more limited than in Parkinson disease, it is now substantial enough to address modification of diagnostic criteria to include the potential for cognitive impairment at any stage of the disease.
Multiple biological factors may play a role when cognitive decline is observed in older health adults.
Cognitive dysfunction may be a sign of prodromal Parkinson disease.
Mechanisms including silent cerebral infarct, microemboli, microbleedings, and cerebral hypoperfusion may be responsible for the link between atrial fibrillation and cognitive decline.
SCD is associated with increased entorhinal cortical tau burden and β-amyloid burden in healthy older adults.
Individuals with prevalent dementia and any nursing home use had especially high 1-year mortality.
Cognitive dysfunction may be the result of lower intracerebral vasomotor reactivity which is linked to PHPT.
Older adults with sleep-disordered breathing have a 26% greater risk for developing cognitive impairment and a small risk for deteriorating executive function.
Previous reports have suggested that statins or the low levels of LDL cholesterol they promote may have an adverse impact on cognition.
Findings from this trial challenge current recommended systolic blood pressure targets for older adults.
There is no association between use of cardiovascular medication and cognitive impairment in older adults.
Visual dysfunction is associated with poor cognitive function in older adults.
Cognitive deficits can be caused by sleep-disordered breathing.
An increase in weight ≥5% was associated with lower cognitive scores.
Patients with the highest predictive scores faced a greater risk of developing cognitive impairment and dementia in the first 10 years after disease onset.
Many residents in nursing homes with cognitive impairments may be taking potentially inappropriate medications.
Light therapy has a moderate effect on behavioral disturbances and depression for people with cognitive impairment.
Youth who have bipolar disorder are not affected by a decline in cognitive function into adulthood.
Improved cognitive function in older adults is being linked to the Mediterranean diet.
Dopamine deficiency, decreases in cortical thickness and volume in certain areas of the brain was predictive of cognitive decline.
The main differentiating factor was the presence of the APOE ε4 allele.
Older adults with chronic pain have been found to have poorer memory and executive function than their younger counterparts.
Cognitive dysfunction is 3 times higher in patients with systemic lupus erythematosus.
An intensive lifestyle intervention including diet and exercise resulted in no improvements in cognitive impairment.
Patients with Alzheimer's disease may have higher serum IL-6 levels than subjects with mild cognitive impairment and healthy controls.
Cognitive fatigue and anxiety are common symptoms reported by patients with multiple sclerosis.
Chronic use of low-dose aspirin was not associated with onset of dementia or cognitive impairment, but was also not associated with significantly better global cognition.
Patients with schizophrenia, schizoaffective disorder, and psychotic bipolar disorder were examined for anticholinergic burden.
Participants with the Met allele lost memory and cognitive skills more rapidly than those without the gene mutation.
Patients with subclinical hypothyroidism scored worse on tests of processing speed than patients with normal thyroid function.
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