Cognitive Impairment

Cognitive Decline in Men Linked to Low Serum Sodium

Cognitive Decline in Men Linked to Low Serum Sodium

For community-dwelling older men, low serum sodium is associated with cognitive impairment and cognitive decline.

Solanezumab Has No Effect on Cognitive Decline in Alzheimer Disease

Solanezumab Has No Effect on Cognitive Decline in Alzheimer Disease

Solanezumab does not alter cognitive decline in patients with mild Alzheimer disease.

Lifestyle Intervention May Improve Cognition in APOEε4 Carriers

Lifestyle Intervention May Improve Cognition in APOEε4 Carriers

In older at-risk individuals, even APOE ε4 carriers, a multidomain lifestyle intervention seems to be beneficial.

Elderly With Cognitive Impairment More Likely to Experience Falls

Elderly With Cognitive Impairment More Likely to Experience Falls

Cognitive therapies may help reduce falls in order adults.

No Cognitive Improvement With Idalopirdine in Mild Alzheimer Disease

No Cognitive Improvement With Idalopirdine in Mild Alzheimer Disease

For patients with mild-to-moderate Alzheimer disease, the use of idalopirdine does not improve cognition.

Guidelines: AAN Recommends Exercise, Cautious Prescribing for Patients With Mild Cognitive Impairment

Guidelines: AAN Recommends Exercise, Cautious Prescribing for Patients With Mild Cognitive Impairment

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A lower education level was associated with higher MCI prevalence in 8 of the class I studies.

Subcortical Microinfarcts Associated With Decreased Blood Pressure in Elderly

Subcortical Microinfarcts Associated With Decreased Blood Pressure in Elderly

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Greater yearly declines in systolic and diastolic blood pressure were noted in individuals with subcortical microinfarcts.

Risk for Cognitive Decline, Dementia Linked to Age-Related Hearing Loss

Risk for Cognitive Decline, Dementia Linked to Age-Related Hearing Loss

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Clinicians might benefit from standard guidelines on how to assess and refer patients with hearing loss.

Increasing Leafy Vegetable Intake May Boost Cognition

Increasing Leafy Vegetable Intake May Boost Cognition

Intake of nutrients in green leafy vegetables is linked to a slower cognitive decline.

Predicting Risk for Cognitive Impairment Based on Age, Mini-Mental Exam

Predicting Risk for Cognitive Impairment Based on Age, Mini-Mental Exam

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Charts may help identify individuals who may benefit most from early interventions to help preserve cognition.

Amyloid, Tau Patterns in Parkinson's Do Not Differ Based on Cognitive Status

Amyloid, Tau Patterns in Parkinson's Do Not Differ Based on Cognitive Status

In Parkinson's patients who are cognitively normal or have mild cognitive impairment, patterns of cortical β-amyloid and tau are not different.

Obesity and Alzheimer Disease: Exploring Risk Modification

Obesity and Alzheimer Disease: Exploring Risk Modification

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Throughout the life course, higher body mass index and obesity are linked to cognitive decline, brain atrophy, reduced white matter and integrity of the blood-brain barrier, and elevated risk for late-onset Alzheimer disease.

Anticholinergic Cognitive Burden Scale Identifies Dose-Related Adverse Outcomes

Anticholinergic Cognitive Burden Scale Identifies Dose-Related Adverse Outcomes

The ACB scale shows good dose-response relationships between anticholinergic burden and adverse outcomes for older adults.

Predicting Risk of Cognitive Decline With Nocturnal Sleep Blood Pressure

Predicting Risk of Cognitive Decline With Nocturnal Sleep Blood Pressure

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An approximately 1-SD increase in SBP correlated with lower scores for 2 tests that assessed for brain damage, dementia, and task switching.

Cognitive Impairment in Multi-System Atrophy: Is It Time to Update Diagnostic Criteria?

Cognitive Impairment in Multi-System Atrophy: Is It Time to Update Diagnostic Criteria?

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Although evidence of cognitive impairment in MSA is admittedly more limited than in Parkinson disease, it is now substantial enough to address modification of diagnostic criteria to include the potential for cognitive impairment at any stage of the disease.

Subjective Cognitive Decline Associated With Tauopathy and Global β-Amyloid Burden

Subjective Cognitive Decline Associated With Tauopathy and Global β-Amyloid Burden

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Multiple biological factors may play a role when cognitive decline is observed in older health adults.

Parkinsonism Diagnosis Linked to Cognitive Deficits

Parkinsonism Diagnosis Linked to Cognitive Deficits

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Cognitive dysfunction may be a sign of prodromal Parkinson disease.

Atrial Fibrillation Associated With Cognitive Decline

Atrial Fibrillation Associated With Cognitive Decline

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Mechanisms including silent cerebral infarct, microemboli, microbleedings, and cerebral hypoperfusion may be responsible for the link between atrial fibrillation and cognitive decline.

Global Tau Burden Linked to Cognitive Decline

Global Tau Burden Linked to Cognitive Decline

SCD is associated with increased entorhinal cortical tau burden and β-amyloid burden in healthy older adults.

Nursing Home Use Increased With Cognitive Impairment

Nursing Home Use Increased With Cognitive Impairment

Individuals with prevalent dementia and any nursing home use had especially high 1-year mortality.

Vascular Dysfunction Compromises Cognition in Hyperparathyroidism

Vascular Dysfunction Compromises Cognition in Hyperparathyroidism

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Cognitive dysfunction may be the result of lower intracerebral vasomotor reactivity which is linked to PHPT.

Sleep-Disordered Breathing Predicts Risk for Cognitive Impairment in Elderly

Sleep-Disordered Breathing Predicts Risk for Cognitive Impairment in Elderly

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Older adults with sleep-disordered breathing have a 26% greater risk for developing cognitive impairment and a small risk for deteriorating executive function.

Evolocumab Has No Effect on Cognition in Patients Attaining Very Low Levels of LDL Cholesterol

Evolocumab Has No Effect on Cognition in Patients Attaining Very Low Levels of LDL Cholesterol

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Previous reports have suggested that statins or the low levels of LDL cholesterol they promote may have an adverse impact on cognition.

Lower Systolic Blood Pressure Targets May Benefit Cognition in Black Patients

Lower Systolic Blood Pressure Targets May Benefit Cognition in Black Patients

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Findings from this trial challenge current recommended systolic blood pressure targets for older adults.

No Association Between Cardiovascular Drugs and Cognitive Impairment

No Association Between Cardiovascular Drugs and Cognitive Impairment

There is no association between use of cardiovascular medication and cognitive impairment in older adults.

Visual Impairment Linked to Cognitive Dysfunction in Seniors

Visual Impairment Linked to Cognitive Dysfunction in Seniors

Visual dysfunction is associated with poor cognitive function in older adults.

Sleep-Disordered Breathing Associated With Cognitive Dysfunction

Sleep-Disordered Breathing Associated With Cognitive Dysfunction

Cognitive deficits can be caused by sleep-disordered breathing.

Cognitive Decline Related to Site-Specific Mid-Life Adiposity

Cognitive Decline Related to Site-Specific Mid-Life Adiposity

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An increase in weight ≥5% was associated with lower cognitive scores.

Algorithm Accurately Predicts Cognitive Decline in Parkinson's Disease

Algorithm Accurately Predicts Cognitive Decline in Parkinson's Disease

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Patients with the highest predictive scores faced a greater risk of developing cognitive impairment and dementia in the first 10 years after disease onset.

Cognitively Impaired Seniors Likely to be Taking Inappropriate Medications

Cognitively Impaired Seniors Likely to be Taking Inappropriate Medications

Many residents in nursing homes with cognitive impairments may be taking potentially inappropriate medications.

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