Diabetes

Diabetes, Obesity Linked to Cortical Atrophy

Diabetes, Obesity Linked to Cortical Atrophy

The researchers found that global mean cortical thickness was lower in the overweight/obese T2DM group.

Intensive Lifestyle Intervention Holds No Benefit for Cognitive Impairment: Analysis

Intensive Lifestyle Intervention Holds No Benefit for Cognitive Impairment: Analysis

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An intensive lifestyle intervention including diet and exercise resulted in no improvements in cognitive impairment.

Obesity Linked to Brain Function Abnormalities in Diabetics

Obesity Linked to Brain Function Abnormalities in Diabetics

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In addition to brain imaging, patients underwent cognitive tests to assess memory, executive function, and psychomotor speed.

Overactive Bladder Drugs Tied to Increased Dementia Risk in Diabetes

Overactive Bladder Drugs Tied to Increased Dementia Risk in Diabetes

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Clinicians must keep this potentially increased risk in mind when prescribing long-term use of a specific anticholinergic drug to patients with DM suffering from OAB.

Insulin Resistance Affects Cognition Later in Life

Insulin Resistance Affects Cognition Later in Life

The researchers found that higher baseline HOMA-IR and fasting insulin levels were independent predictors of poorer verbal fluency performance.

Insulin-Controlled Diabetes Linked to Increased Stroke Risk in AFib

Insulin-Controlled Diabetes Linked to Increased Stroke Risk in AFib

The increased risk of stroke was only observed among patients with diabetes controlled by insulin.

Poor Sleep Quality, Short Duration May Increase Risk of Gestational Diabetes

Poor Sleep Quality, Short Duration May Increase Risk of Gestational Diabetes

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Women who were pregnant and slept for less than 6 hours per night or had poor sleep quality had a greater risk of developing gestational diabetes.

Delayed Sleep Onset Linked to Insulin Resistance in Women

Delayed Sleep Onset Linked to Insulin Resistance in Women

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The study supports previous findings of hyperarousal of the inflammatory system as a mechanism of insulin resistance.

Depressive Disorder in Type 2 Diabetes

Depressive Disorder in Type 2 Diabetes

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Patients with type 2 diabetes and major depressive disorder spent a significant amount of time experiencing depressive episodes.

Ghrelin Levels May Predict Cognitive Impairment in Diabetes

Ghrelin Levels May Predict Cognitive Impairment in Diabetes

Ghrelin was a significant predictor for executive function impairment in patients with T2DM.

Pioglitazone Reduces Diabetes Risk in Patients With Ischemic Stroke

Pioglitazone Reduces Diabetes Risk in Patients With Ischemic Stroke

The findings are relevant for patients with insulin resistance but no history of diabetes.

Statins May Protect Against Parkinson's Disease in Diabetes

Statins May Protect Against Parkinson's Disease in Diabetes

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All but one type of statin was associated with a dose-dependent neurprotective benefit against Parkinson's.

Diabetes May Alter Gray Matter Volume in Adolescents

Diabetes May Alter Gray Matter Volume in Adolescents

Differences in brain volume have previously been found in adults with Type 2 diabetes.

Selective Serotonin Reuptake Inhibitor Use in Diabetes Increases Stroke Mortality

Selective Serotonin Reuptake Inhibitor Use in Diabetes Increases Stroke Mortality

Selective serotonin reuptake inhibitor use increases risk for patients hospitalized with stroke.

Hypoglycemia, Sleep Loss Prolongs Recovery From Cognitive Impairment

Hypoglycemia, Sleep Loss Prolongs Recovery From Cognitive Impairment

Sleep deprivation does not worsen impairment in type 1 diabetes, but prolongs recovery.

Long-Term Weight Loss May Reduce Diabetes' Effect on the Brain

Long-Term Weight Loss May Reduce Diabetes' Effect on the Brain

Long-term intervention was associated with lower white matter hyperintensity volume.

Type 1 Diabetes and Epilepsy: What's the Connection?

Type 1 Diabetes and Epilepsy: What's the Connection?

The risk of epilepsy is nearly 3 times greater in patients with Type 1 diabetes.

Autism May Raise Risk for Type 2 Diabetes

Autism May Raise Risk for Type 2 Diabetes

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Type 2 diabetes appears to be more common in adolescents with autism spectrum disorders.

Diabetes Drugs May Slow Disease Activity in Multiple Sclerosis

Diabetes Drugs May Slow Disease Activity in Multiple Sclerosis

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The drugs have an anti-inflammatory effect in patients with both MS and metabolic syndrome.

CPAP Improves Glucose Control in Pts With Sleep Apnea, Type 2 Diabetes

CPAP Improves Glucose Control in Pts With Sleep Apnea, Type 2 Diabetes

After 6 months, the CPAP group saw a greater decrease in HbA1c levels compared to controls.

Pioglitazone May Prevent Recurrent Stroke, Heart Attack in Patients Without Diabetes

Pioglitazone May Prevent Recurrent Stroke, Heart Attack in Patients Without Diabetes

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Patients taking pioglitazone saw a 24% reduction in risk for recurrent stroke or myocardial infarction compared to placebo.

Dementia Risk Elevated in Patients with Type 2 Diabetes

Dementia Risk Elevated in Patients with Type 2 Diabetes

People with type 2 diabetes have approximately a 60% greater risk of dementia those those without.

Well-Controlled HbA1c in Diabetes Linked to Lower Dementia Risk

Well-Controlled HbA1c in Diabetes Linked to Lower Dementia Risk

Poorly controlled HbA1c levels were associated with a 50% greater risk of dementia later in life.

Diabetes May Contribute to Tau Buildup Independent of Dementia

Diabetes May Contribute to Tau Buildup Independent of Dementia

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Those with diabetes had higher concentrations of total tau in CSF, as well as thinner cortical thickness regardless of dementia diagnosis.

Insulin Resistance in Women May Indicate Risk of Cognitive Decline

Insulin Resistance in Women May Indicate Risk of Cognitive Decline

Higher HOMA-IR score was linked to poorer language skills in women.

Animal Model Links Hippocampal Insulin Resistance to Neuroplasticity

Animal Model Links Hippocampal Insulin Resistance to Neuroplasticity

Hippocampal-specific insulin resistance in a rat model was shown to downregulate insulin receptor expression.

Type 1 Diabetes Patients Very Likely to Develop Dementia

Type 1 Diabetes Patients Very Likely to Develop Dementia

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Those with type 1 diabetes were 61% more likely to develop dementia after adjustments.

Glitazone Use May Reduce Parkinson's Risk

Glitazone Use May Reduce Parkinson's Risk

Reduced risk was only seen in patients actively taking glitazones.

Addressing Peripheral Neuropathy in Prediabetes

Addressing Peripheral Neuropathy in Prediabetes

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Addressing neuropathy early on in prediabetes is essential to successful symptom management.

Diabetes Complications May Raise Risk of Dementia

Diabetes Complications May Raise Risk of Dementia

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Those with more complications from diabetes had a higher risk of developing dementia.

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