Epilepsy Headlines

Chronic Traumatic Encephalopathy Uncommon in Treatment-Refractory Epilepsy

Chronic Traumatic Encephalopathy Uncommon in Treatment-Refractory Epilepsy

While epilepsy-related head trauma was common, 9 of 10 patients displayed no evidence of CTE.

FDA Approves Smart Watch for Epilepsy Management

FDA Approves Smart Watch for Epilepsy Management

The FDA has cleared the Embrace smart watch for managing epilepsy.

Cannabidiol Reduces Drop Seizures in Lennox-Gastaut Syndrome

Cannabidiol Reduces Drop Seizures in Lennox-Gastaut Syndrome

Add-on cannabidiol is associated with reduced monthy drop seizure frequency in patients with Lennox-Gastaut sydrome associated drop seizures.

Focal Epilepsy Linked to Increased Risk for Mood Disorders

Focal Epilepsy Linked to Increased Risk for Mood Disorders

Clinicians should evaluate their patients, especially patients with focal epilepsy, for mood disorders.

High Doses of Topiramate for Epilepsy in Pregnancy Increase Risks for Oral Clefts in Offspring

High Doses of Topiramate for Epilepsy in Pregnancy Increase Risks for Oral Clefts in Offspring

Women receiving topiramate for epilepsy were exposed to high cumulative doses, increasing the risk for oral clefts in offspring.

Seizure Control Diminishes With Subsequent Antiepileptic Drug Therapy

Seizure Control Diminishes With Subsequent Antiepileptic Drug Therapy

Patients with tough-to-treat seizures may require nonpharmacologic treatment such as resective surgery.

More Than One-Third of New Cases of Epilepsy Are Treatment Refractory

More Than One-Third of New Cases of Epilepsy Are Treatment Refractory

Over one-third of patients with newly diagnosed epilepsy do not respond to antiepileptic drug treatment.

Treating Levetiracetam-Induced Behavioral Effects With Vitamin B6

Treating Levetiracetam-Induced Behavioral Effects With Vitamin B6

Vitamin B6 was found to effectively treat the behavioral adverse effects seen with levetiracetam.

Myoclonus Reported With Gabapentin, Pregabalin Use

Myoclonus Reported With Gabapentin, Pregabalin Use

Research has found that gabapentin and pregabalin induced myoclonus is often seen but is rarely documented.

Folate Supplementation May Help Reduce Autistic Traits in Children Exposed to AEDs In Utero

Folate Supplementation May Help Reduce Autistic Traits in Children Exposed to AEDs In Utero

Children who are exposed to AEDs in utero may have a reduced risk of autistic traits.

Evaluating Antiepileptic Drug Safety in Elderly Patients

Evaluating Antiepileptic Drug Safety in Elderly Patients

Lamotrigine and levetiracetam are just as effective as other AEDs, and are better tolerated as well.

Cannabidiol Under Priority Review for Treatment of Lennox-Gastaut, Dravet Syndromes

Cannabidiol Under Priority Review for Treatment of Lennox-Gastaut, Dravet Syndromes

The FDA has accepted for filing with Priority Review the NDA for cannabidiol as seizure treatment.

Prepregnancy Seizure History May Predict Antepartum Seizure Risk

Prepregnancy Seizure History May Predict Antepartum Seizure Risk

The findings emphasize the importance of seizure control before pregnancy in women with epilepsy.

Brodmann Area 25 May Play Pivotal Role in Controlling Blood Pressure

Brodmann Area 25 May Play Pivotal Role in Controlling Blood Pressure

Stimulation of the other brain structures resulted in no significant blood pressure changes among the studied participants.

Severe Refractory Focal Epilepsy May Benefit From Add-On Perampanel

Severe Refractory Focal Epilepsy May Benefit From Add-On Perampanel

In patients with severe refractory focal epilepsy, add-on treatment with perampanel may be beneficial.

Identifying Pediatric Seizures With Hemispheric Regional Cerebral Oxygen Saturation

Identifying Pediatric Seizures With Hemispheric Regional Cerebral Oxygen Saturation

The findings further the utility of cerebral oximetry as a neurological assessment tool.

Reducing Seizure Frequency in Dravet Syndrome With Low-Dose Fenfluramine

Reducing Seizure Frequency in Dravet Syndrome With Low-Dose Fenfluramine

ZX008 has received Orphan Drug designation and Fast Track designation by the FDA for the treatment of Dravet syndrome.

Effect of Maternal Antibiotic Use on Neonatal Seizure Risk

Effect of Maternal Antibiotic Use on Neonatal Seizure Risk

Researchers from the University of Colorado reported on whether or not maternal antibiotic use during labor increased the risk of seizure for the neonate.

Mental Health Comorbidities Common in Epilepsy

Mental Health Comorbidities Common in Epilepsy

Suicide-related behavior was not found to be linked with epilepsy or the type of antiepileptic drug they were on.

Seizure Incidence Stable in Prostate Cancer Treated With Enzalutamide

Seizure Incidence Stable in Prostate Cancer Treated With Enzalutamide

Treatment with enzalutamide for metastatic castration-resistant prostate cancer patients is not linked with increased seizure incidence.

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