The FDA-sponsored study sought to evaluate the bioequivalence of 2 generic forms of the popular epilepsy treatment lamotrigine.
Changes in serum concentrations of other anti-epileptic drugs were not found to be significant.
Those with uncomplicated epilepsy who were seizure-free for five years had social outcomes comparable to their siblings.
The finding isn't overly surprising since the types of brain abnormalities seen in Zika-affected newborns have been linked to seizures and epilepsy in the past.
Epileptic phenomena are an important component of the dysfunction of the neuronal networks affected by Alzheimer's disease.
Results from 2 phase 3 clinical trials demonstrated efficacy of adjunctive cannabidiol for the treatment of drop seizures in Lennox-Gastaut syndrome.
A newly published guideline shines light on sudden unexpected death in epilepsy and how clinicians can help prevent it.
Sepsis is associated with pathways that lead to permanent neurological sequelae.
Women with higher body mass index were associated with children with a greater epilepsy incidence.
Underlying pathophysiological mechanisms may connect depression and epilepsy.
Lamotrigine and carbamazepine may represent safer treatment alternatives for girls and women who are or who might become pregnant.
In patients with lorazepam-resistant status epilepticus, treatment with lacosamide had comparable efficacy and safety as sodium valproate.
Sunovion has filed a supplemental NDA with the FDA to expand the indication for Aptiom to pediatric patients with partial onset seizures.
In people with Dravet syndrome, language impairments increase with age, suggesting that early intervention with targeted oral motor therapies may be helpful.
Elderly patients with neurologic comorbidities such as stroke or dementia had an increased risk for epilepsy or seizures.
There is as much as a 32% risk for vigabatrin-associated brain abnormalities in patients with infantile spasms.
Patients taking enzyme-inducing antiepileptic drugs and hormonal contraceptives face a greater risk of unintended pregnancy.
Participants reported improved adherence to a modified Atkins diet compared with the popular but restrictive ketogenic diet.
This study identified a feature of the epileptic brain that evolves slowly and differs fundamentally in well-controlled and poorly controlled epilepsy.
A subset of epilepsy cases of unknown etiology may be secondary to the production of autoantibodies.
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