Epilepsy Headlines

Lamotrigine Use During Pregnancy Not Associated With Birth Defects

Lamotrigine Use During Pregnancy Not Associated With Birth Defects

Among infants exposed to the medication in utero, none had major or significant malformations.

Some Antiepileptic Drugs Associated With Increased Risk for Toxic Epidermal Necrolysis

Some Antiepileptic Drugs Associated With Increased Risk for Toxic Epidermal Necrolysis

New use of clonazepam, levetiracetam, or topiramate was not associated with Stevens-Johnson syndrome and toxic epidermal necrolysis.

Eclampsia Linked to Higher Relative Risk of Seizure Disorder

Eclampsia Linked to Higher Relative Risk of Seizure Disorder

The relative risk of seizure disorder is higher in women who were affected by eclampsia than those who were not.

FDA Approves Lacosamide for Pediatric Partial-Onset Seizures

FDA Approves Lacosamide for Pediatric Partial-Onset Seizures

The FDA has approved lacosamide for treating pediatric patients with partial-onset seizures.

Cannabidiol Product Concentration Varies in Products Sold Online

Cannabidiol Product Concentration Varies in Products Sold Online

Of 84 products sampled, 42.85% were underlabeled and 26.19% were overlabeled.

Development of Guillain-Barré Syndrome Associated With Zika Virus Infection

Development of Guillain-Barré Syndrome Associated With Zika Virus Infection

Infection with the Zika virus may increase the risk for development of Guillain-Barré syndrome.

Surgery Reduces Seizures in Treatment-Refractory Epilepsy

Surgery Reduces Seizures in Treatment-Refractory Epilepsy

Surgery can improve freedom from seizures in pediatric patients with drug-resistant epilepsy.

Infant Respiratory Distress Syndrome Increases Childhood Epilepsy Risk

Infant Respiratory Distress Syndrome Increases Childhood Epilepsy Risk

Infants born at 32-36 weeks gestation from 1978-2008 with infant respiratory distress syndrome were enrolled to evaluate the long term risk of epilepsy.

Model Helps Identify Seizure Risk in Critically Ill

Model Helps Identify Seizure Risk in Critically Ill

A model comprising 6 variables can identify the probability of seizure for critically ill patients.

Antiepileptic Drugs Linked to Impaired Bone and Muscle Development in Children

Antiepileptic Drugs Linked to Impaired Bone and Muscle Development in Children

Previous research found an association between AED use and reduced bone density in adults.

Dose "Ceiling" May Exist for Epilepsy Treated With Lamotrigine

Dose "Ceiling" May Exist for Epilepsy Treated With Lamotrigine

A "ceiling" may exist for lamotrigine therapy above which remission from seizures may be unlikely.

FDA Approves Vagus Nerve Stimulator for Refractory Epilepsy

FDA Approves Vagus Nerve Stimulator for Refractory Epilepsy

The system includes a detect-and-respond mode, which is designed to prevent seizures before they start and deliver therapy to stop them if they do.

Seizures More Likely in Patients With Sepsis Than General Population

Seizures More Likely in Patients With Sepsis Than General Population

Patients with sepsis included in this analysis may have presented with other CNS pathologies that could have contributed to seizure risk.

Incidence of Seizures and Epilepsy High in Ischemic Stroke

Incidence of Seizures and Epilepsy High in Ischemic Stroke

Newer antiepileptic drugs were associated with fewer adverse effects in patients with ischemic stroke.

Antiepileptic Drugs Increase Risk of Birth Complications, Poor Fetal Health

Antiepileptic Drugs Increase Risk of Birth Complications, Poor Fetal Health

Pregnant women on antiepileptic drugs are at a higher risk of giving birth to a premature and SGA infant.

FDA Approves Expanded Seizure Indication for Aptiom

FDA Approves Expanded Seizure Indication for Aptiom

The FDA has approved an expanded indication for Aptiom to treat pediatric partial-onset seizures.

FDA Approves Briviact for Partial-Onset Seizure Monotherapy

FDA Approves Briviact for Partial-Onset Seizure Monotherapy

Briviact was initially approved as adjunct treatment for partial-onset seizures.

Buccal, Nasal Midazolam Most Cost-Effective for Pediatric Status Epilepticus

Buccal, Nasal Midazolam Most Cost-Effective for Pediatric Status Epilepticus

Rectal diazepam is currently the only FDA-approved treatment for pediatric status epilepticus.

Epilepsy Incidence Rates on the Rise in US Adults

Epilepsy Incidence Rates on the Rise in US Adults

Over 1% of the US population reported active or current epilepsy in 2015.

Cannabidiol May Impact Antiepileptic Drug Levels in Refractory Epilepsy

Cannabidiol May Impact Antiepileptic Drug Levels in Refractory Epilepsy

While several studies have demonstrated efficacy in refractory epilepsy, it is still not clear how cannabidiol may have an impact on current epilepsy treatments.

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