Epilepsy Headlines

FDA Approves Expanded Seizure Indication for Aptiom

FDA Approves Expanded Seizure Indication for Aptiom

The FDA has approved an expanded indication for Aptiom to treat pediatric partial-onset seizures.

FDA Approves Briviact for Partial-Onset Seizure Monotherapy

FDA Approves Briviact for Partial-Onset Seizure Monotherapy

Briviact was initially approved as adjunct treatment for partial-onset seizures.

Buccal, Nasal Midazolam Most Cost-Effective for Pediatric Status Epilepticus

Buccal, Nasal Midazolam Most Cost-Effective for Pediatric Status Epilepticus

Rectal diazepam is currently the only FDA-approved treatment for pediatric status epilepticus.

Epilepsy Incidence Rates on the Rise in US Adults

Epilepsy Incidence Rates on the Rise in US Adults

Over 1% of the US population reported active or current epilepsy in 2015.

Cannabidiol May Impact Antiepileptic Drug Levels in Refractory Epilepsy

Cannabidiol May Impact Antiepileptic Drug Levels in Refractory Epilepsy

While several studies have demonstrated efficacy in refractory epilepsy, it is still not clear how cannabidiol may have an impact on current epilepsy treatments.

Brexanolone Safe, Tolerable as Adjunctive Therapy in Super-Refractory Status Epilepticus

Brexanolone Safe, Tolerable as Adjunctive Therapy in Super-Refractory Status Epilepticus

Brexanolone may help wean patients with super-refractory status epilepticus off of third-line agents.

Review Supports Current NICE Guidelines for Tx of Partial Onset Seizures

Review Supports Current NICE Guidelines for Tx of Partial Onset Seizures

For people with seizures, levetiracetam is more effective than carbamazepine and lamotrigine.

Genetic Testing Justified in Early Childhood Epilepsy

Genetic Testing Justified in Early Childhood Epilepsy

In children with epilepsy, genetic investigation that emphasizes sequencing tests should be part of the initial evaluation.

Epilepsy Diagnosis, Outcomes Associated With Depression Severity

Epilepsy Diagnosis, Outcomes Associated With Depression Severity

Previous research has found a higher prevalence of depression before and after an epilepsy diagnosis.

Vagus Nerve Stimulation Therapy for Epilepsy: FDA Expands Age Range

Vagus Nerve Stimulation Therapy for Epilepsy: FDA Expands Age Range

The FDA has expanded the age range for the VNS Therapy system.

Partial-Onset Seizure Treatment Discontinued

Partial-Onset Seizure Treatment Discontinued

Potiga tablets have been discontinued due to the limited use of the medicine.

Evaluating the Bioequivalence of Generic Lamotrigine for Epilepsy

Evaluating the Bioequivalence of Generic Lamotrigine for Epilepsy

The FDA-sponsored study sought to evaluate the bioequivalence of 2 generic forms of the popular epilepsy treatment lamotrigine.

Ketogenic Diet: Evaluating Effects on Epilepsy Treatments

Ketogenic Diet: Evaluating Effects on Epilepsy Treatments

Changes in serum concentrations of other anti-epileptic drugs were not found to be significant.

Quality of Life Outcomes in Uncomplicated Childhood Epilepsy

Quality of Life Outcomes in Uncomplicated Childhood Epilepsy

Those with uncomplicated epilepsy who were seizure-free for five years had social outcomes comparable to their siblings.

Zika Virus May Trigger Epilepsy in Infants

Zika Virus May Trigger Epilepsy in Infants

The finding isn't overly surprising since the types of brain abnormalities seen in Zika-affected newborns have been linked to seizures and epilepsy in the past.

Undetected Seizures May Play a Role in Alzheimer's Pathology

Undetected Seizures May Play a Role in Alzheimer's Pathology

Epileptic phenomena are an important component of the dysfunction of the neuronal networks affected by Alzheimer's disease.

Drop Seizure Frequency in Lennox-Gastaut Decreased With Cannabidiol

Drop Seizure Frequency in Lennox-Gastaut Decreased With Cannabidiol

Results from 2 phase 3 clinical trials demonstrated efficacy of adjunctive cannabidiol for the treatment of drop seizures in Lennox-Gastaut syndrome.

New Guideline Tackles Sudden Unexpected Death in Epilepsy

New Guideline Tackles Sudden Unexpected Death in Epilepsy

A newly published guideline shines light on sudden unexpected death in epilepsy and how clinicians can help prevent it.

Sepsis Associated With Long-term Seizure Risk

Sepsis Associated With Long-term Seizure Risk

Sepsis is associated with pathways that lead to permanent neurological sequelae.

Maternal BMI May Affect Epilepsy Risk in Offspring

Maternal BMI May Affect Epilepsy Risk in Offspring

Women with higher body mass index were associated with children with a greater epilepsy incidence.

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