Epilepsy and Seizures

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Managing Status Epilepticus in Palliative Care: Accounting for Patient and Family Experience

Managing Status Epilepticus in Palliative Care: Accounting for Patient and Family Experience

There are considerations for treating these seizures as part of the overall goals of palliative care, which include the family's experience.

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Oral Film Formulation of Clobazam Gets FDA Approval for LGS

Oral Film Formulation of Clobazam Gets FDA Approval for LGS

Aquestive Therapeutics announced that the FDA has approved Sympazan oral film as adjunctive treatment of seizures associated with LGS in patients aged ≥2 years old.

Circadian, Circaseptan Rhythms Prevalent in Epileptic Seizure Cycles

Circadian, Circaseptan Rhythms Prevalent in Epileptic Seizure Cycles

Researchers used analytic techniques from circular statistics to quantify the prevalence, frequency, and strength of seizure cycles in patients with epilepsy.

Resective Epilepsy Surgery Reduces Seizures, Improves Social Functioning in Lennox-Gastaut Syndrome

Resective Epilepsy Surgery Reduces Seizures, Improves Social Functioning in Lennox-Gastaut Syndrome

Better social competence and adaptive behavior was achieved by seizure-free patients at post-surgery follow-ups compared with patients with persistent seizures (P <.05).

Combining Vigabatrin, Hormone Therapy Effective for Infantile Spasms

Combining Vigabatrin, Hormone Therapy Effective for Infantile Spasms

Results suggest that prednisolone may be associated with a reduced chance of achieving electroclinical response when compared with tetracosactide.

Epidiolex Now Available to Treat Seizures Associated With LGS, Dravet Syndrome

Epidiolex Now Available to Treat Seizures Associated With LGS, Dravet Syndrome

The Food and Drug Administration (FDA) approved the treatment in June 2018, making it the first prescription pharmaceutical formulation of highly-purified, plant-derived cannabidiol, as well as the first treatment indicated for patients with Dravet syndrome.

Predictors for Epilepsy Following Acute Symptomatic Neonatal Seizures Remain Elusive

Predictors for Epilepsy Following Acute Symptomatic Neonatal Seizures Remain Elusive

The researchers sought to identify risk factors for seizures in this population by reviewing hospital records.

High-Frequency Oscillations Not a Good Predictor of Outcomes After Epilepsy Surgery

High-Frequency Oscillations Not a Good Predictor of Outcomes After Epilepsy Surgery

HFOs were predictors of good or poor surgical outcome in 69.2% of patients, resulting in a modest validation of the researchers' hypothesis.

Unintended Pregnancy Common in Women With Epilepsy

Unintended Pregnancy Common in Women With Epilepsy

It is likely that both maternal age and socioeconomic status contribute to the higher rates of pregnancy in WWE compared with women without epilepsy.

Fycompa Approved for Younger Epilepsy Patients With Partial-Onset Seizures

Fycompa Approved for Younger Epilepsy Patients With Partial-Onset Seizures

Safety data for Fycompa was consistent with the safety profile in adult populations without the need for weight-based dosing.

DEA Reschedules Marijuana-Based Drug Epidiolex

DEA Reschedules Marijuana-Based Drug Epidiolex

Drugs with a Schedule V classification have proven medical use and low abuse potential.

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