Epilepsy and Seizures

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Vagus Nerve Stimulation in Pediatric Epilepsy: Weighing the Risks and Benefits

Vagus Nerve Stimulation in Pediatric Epilepsy: Weighing the Risks and Benefits

Studies that have evaluated the use of VNS in children, including those as young as 6 months old, and have generally concluded that it is well tolerated and improves quality of life.

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Significant Variations in Epilepsy Surgical Strategy, Deficit Reporting Exist

Significant Variations in Epilepsy Surgical Strategy, Deficit Reporting Exist

This widespread variation in strategies may contribute to undesirable outcomes that are characterized by poor seizure control and added deficits.

Brivaracetam Effective for Reducing Seizures in Patients with Epileptic Encephalopathies

Brivaracetam Effective for Reducing Seizures in Patients with Epileptic Encephalopathies

Although 2 patients experienced an increase in seizure frequency, the remaining patients did not experience a change in frequency.

Add-On Cannabidiol Reduces Seizure Frequency in Treatment-Refractory Epilepsy

Add-On Cannabidiol Reduces Seizure Frequency in Treatment-Refractory Epilepsy

Countable seizure types were recorded in parents' and caregivers' clinical diaries during a 4-week baseline period.

Clinical Factors Influencing Neuroimaging Yield in Nonindex Seizures Identified

Clinical Factors Influencing Neuroimaging Yield in Nonindex Seizures Identified

The investigators sought to detect whether neuroimaging during an emergency department visit was associated with acute changes in the management of patients.

Late-Onset Epilepsy Linked to APOE ε4, Smoking, Diabetes

Late-Onset Epilepsy Linked to APOE ε4, Smoking, Diabetes

The risk for late-onset epilepsy was lower in patients with higher physical activity levels and moderate alcohol intake.

Outcomes After Seizure Recurrence Upon AED Withdrawal Following Temporal Lobectomy

Outcomes After Seizure Recurrence Upon AED Withdrawal Following Temporal Lobectomy

Recurrence of seizures was reported in 28.2% of patients who attempted withdrawal.

Sympazan Oral Film Granted Tentative Approval for Lennox-Gastaut Syndrome

Sympazan Oral Film Granted Tentative Approval for Lennox-Gastaut Syndrome

Clobazam is currently available as oral tablets and suspension under the trade name Onfi (Lundbeck).

Everolimus, Sirolimus Generally Safe for Epilepsy in Tuberous Sclerosis Complex

Everolimus, Sirolimus Generally Safe for Epilepsy in Tuberous Sclerosis Complex

Approximately 78% of treated patients experienced at least 1 treatment-related adverse event.

Anticonvulsants Not Associated With Risk for Perinatal Bleeding

Anticonvulsants Not Associated With Risk for Perinatal Bleeding

The findings offer some reassurance for clinicians and for pregnant women who are successfully treated with enzyme-inducing ACDs.

Diacomit Approved for the Treatment of Dravet Sydrome

Diacomit Approved for the Treatment of Dravet Sydrome

Diacomit was evaluated in 2 multicenter, placebo-controlled, double-blind, randomized studies.

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