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International League Against Epilepsy Updates Epilepsy Classification System

International League Against Epilepsy Updates Epilepsy Classification System

The International League Against Epilepsy has revised its epilepsy classification system in an effort to inform epilepsy research and aid drug development.

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Zika Virus May Trigger Epilepsy in Infants

Zika Virus May Trigger Epilepsy in Infants

The finding isn't overly surprising since the types of brain abnormalities seen in Zika-affected newborns have been linked to seizures and epilepsy in the past.

Maternal BMI May Affect Epilepsy Risk in Offspring

Maternal BMI May Affect Epilepsy Risk in Offspring

Women with higher body mass index were associated with children with a greater epilepsy incidence.

Epilepsy Risk May Increase After Incident Depression

Epilepsy Risk May Increase After Incident Depression

Underlying pathophysiological mechanisms may connect depression and epilepsy.

Valproate for Epilepsy Poses Greater Risk for Major Congenital Malformations

Valproate for Epilepsy Poses Greater Risk for Major Congenital Malformations

Lamotrigine and carbamazepine may represent safer treatment alternatives for girls and women who are or who might become pregnant.

In Refractory Status Epilepticus, Lacosamide May Be a Good Option

In Refractory Status Epilepticus, Lacosamide May Be a Good Option

In patients with lorazepam-resistant status epilepticus, treatment with lacosamide had comparable efficacy and safety as sodium valproate.

Aptiom Aims for Pediatric Indication for Partial Onset Seizures

Aptiom Aims for Pediatric Indication for Partial Onset Seizures

Sunovion has filed a supplemental NDA with the FDA to expand the indication for Aptiom to pediatric patients with partial onset seizures.

Distinct Phenotype in Dravet Syndrome Helps Outline Treatment

Distinct Phenotype in Dravet Syndrome Helps Outline Treatment

In people with Dravet syndrome, language impairments increase with age, suggesting that early intervention with targeted oral motor therapies may be helpful.

Epilepsy, Seizures Common Among Nursing Home Population

Epilepsy, Seizures Common Among Nursing Home Population

Elderly patients with neurologic comorbidities such as stroke or dementia had an increased risk for epilepsy or seizures.

Vigabatrin Dose Affects Risk for Brain Abnormalities in Infantile Spasms

Vigabatrin Dose Affects Risk for Brain Abnormalities in Infantile Spasms

There is as much as a 32% risk for vigabatrin-associated brain abnormalities in patients with infantile spasms.

Unintended Pregnancy in Epilepsy May Be Linked to Contraceptive, AED Combo

Unintended Pregnancy in Epilepsy May Be Linked to Contraceptive, AED Combo

Patients taking enzyme-inducing antiepileptic drugs and hormonal contraceptives face a greater risk of unintended pregnancy.

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