Epilepsy and Seizures

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A Convenient Truth: The Problem With Seizure Under-Reporting and How to Fix It

A Convenient Truth: The Problem With Seizure Under-Reporting and How to Fix It

Before we begin to rely more heavily on technology for seizure detection, clinician-patient trust needs to improve.

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FDA: Lamotrigine Linked to Potentially Life-Threatening Adverse Reaction

FDA: Lamotrigine Linked to Potentially Life-Threatening Adverse Reaction

Clinicians should conduct a medical evaluation as soon as suspicious symptoms are reported and discontinue lamotrigine if HLH is suspected.

Listening to Sonified EEG Fluctuations May Help Identify Silent Seizures

Listening to Sonified EEG Fluctuations May Help Identify Silent Seizures

In the event where electroencephalograms featured either seizures or seizure-like patterns, nonexpert medical students who auditorily reviewed the electroencephalograms rated samples as seizures with a higher degree of specificity vs experts or nonexpert medical students.

Add-On Cannabidiol for Treatment-Resistant Drop Seizures in Lennox-Gastaut Syndrome

Add-On Cannabidiol for Treatment-Resistant Drop Seizures in Lennox-Gastaut Syndrome

Cannabidiol may be effective as add-on treatment for drop seizures associated with Lennox-Gastaut syndrome.

Afinitor Disperz Approved to Treat TSC-Associated Partial-Onset Seizures

Afinitor Disperz Approved to Treat TSC-Associated Partial-Onset Seizures

The FDA has approved Afinitor Disperz for the adjunctive treatment of patients aged ≥2 years with TSC-associated partial-onset seizures.

Increased Risk of Unnatural Death in People With Epilepsy

Increased Risk of Unnatural Death in People With Epilepsy

The risk of unnatural death is increased among people with epilepsy.

Cannabidiol Safe, Well Tolerated in Children With Dravet Syndrome

Cannabidiol Safe, Well Tolerated in Children With Dravet Syndrome

Because of the small size of the study sample, the findings may be limited to this patient population and may be hard to generalize across all pediatric patients with Dravet syndrome.

EEG Changes in Pediatric BECTS Promoted by Treatment With Levetiracetam, Sulthiame

EEG Changes in Pediatric BECTS Promoted by Treatment With Levetiracetam, Sulthiame

The small sample size included in the study precludes the ability to make generalized statements about electroencephalogram pattern characteristics in the entire pediatric patient population with BECTS.

Early-Life Epilepsy Should Be Urgently Treated With EBM

Early-Life Epilepsy Should Be Urgently Treated With EBM

Best diagnostics and evidence-based treatments should be used from the start of the disease.

Educational Attainment Down With In Utero Exposure to AEDs

Educational Attainment Down With In Utero Exposure to AEDs

Exposure to sodium valproate or a combination of antiepileptic drugs in utero is associated with worse attainment on national educational tests.

Fycompa sNDA Submitted for Pediatric Seizure Indications

Fycompa sNDA Submitted for Pediatric Seizure Indications

The proposed pediatric indications are based on a 2018 Draft Guidance that supports extrapolating efficacy data of approved drugs to treat POS in adults to pediatric patients aged ≥4 years.

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