A "ceiling" may exist for lamotrigine therapy above which remission from seizures may be unlikely.
The system includes a detect-and-respond mode, which is designed to prevent seizures before they start and deliver therapy to stop them if they do.
The CDC has updated the US national estimate of epilepsy prevalence and estimates 3.4 million people are affected by epilepsy.
Patients with sepsis included in this analysis may have presented with other CNS pathologies that could have contributed to seizure risk.
Newer antiepileptic drugs were associated with fewer adverse effects in patients with ischemic stroke.
Pregnant women on antiepileptic drugs are at a higher risk of giving birth to a premature and SGA infant.
The FDA has approved an expanded indication for Aptiom to treat pediatric partial-onset seizures.
Briviact was initially approved as adjunct treatment for partial-onset seizures.
Rectal diazepam is currently the only FDA-approved treatment for pediatric status epilepticus.
Over 1% of the US population reported active or current epilepsy in 2015.
While several studies have demonstrated efficacy in refractory epilepsy, it is still not clear how cannabidiol may have an impact on current epilepsy treatments.
Brexanolone may help wean patients with super-refractory status epilepticus off of third-line agents.
For people with seizures, levetiracetam is more effective than carbamazepine and lamotrigine.
In children with epilepsy, genetic investigation that emphasizes sequencing tests should be part of the initial evaluation.
Previous research has found a higher prevalence of depression before and after an epilepsy diagnosis.
The FDA has expanded the age range for the VNS Therapy system.
Potiga tablets have been discontinued due to the limited use of the medicine.
Woman with SLE complains of headache, confusion, and mild somnolence to the emergency department.
The FDA-sponsored study sought to evaluate the bioequivalence of 2 generic forms of the popular epilepsy treatment lamotrigine.
Changes in serum concentrations of other anti-epileptic drugs were not found to be significant.
Those with uncomplicated epilepsy who were seizure-free for five years had social outcomes comparable to their siblings.
The finding isn't overly surprising since the types of brain abnormalities seen in Zika-affected newborns have been linked to seizures and epilepsy in the past.
Epileptic phenomena are an important component of the dysfunction of the neuronal networks affected by Alzheimer's disease.
Anup Patel, MD, of Nationwide Children's Hospital and The Ohio State University School of Medicine, discusses findings from a dose-ranging study of cannabidiol for the treatment of drop seizures in Lennox-Gastaut syndrome. Scroll to below the video for a full text transcript of Dr Patel's interview.
Results from 2 phase 3 clinical trials demonstrated efficacy of adjunctive cannabidiol for the treatment of drop seizures in Lennox-Gastaut syndrome.
Cynthia Harden, MD, lead author of the new SUDEP guidelines, discusses the development process and what she hopes clinicians will take away from the guidance. Scroll to below the video for a full text transcript of Dr Harden's interview.
A newly published guideline shines light on sudden unexpected death in epilepsy and how clinicians can help prevent it.
Sepsis is associated with pathways that lead to permanent neurological sequelae.
Women with higher body mass index were associated with children with a greater epilepsy incidence.
Underlying pathophysiological mechanisms may connect depression and epilepsy.
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