The International League Against Epilepsy has revised its epilepsy classification system in an effort to inform epilepsy research and aid drug development.
Sunovion has filed a supplemental NDA with the FDA to expand the indication for Aptiom to pediatric patients with partial onset seizures.
In people with Dravet syndrome, language impairments increase with age, suggesting that early intervention with targeted oral motor therapies may be helpful.
Elderly patients with neurologic comorbidities such as stroke or dementia had an increased risk for epilepsy or seizures.
There is as much as a 32% risk for vigabatrin-associated brain abnormalities in patients with infantile spasms.
Patients taking enzyme-inducing antiepileptic drugs and hormonal contraceptives face a greater risk of unintended pregnancy.
Participants reported improved adherence to a modified Atkins diet compared with the popular but restrictive ketogenic diet.
This study identified a feature of the epileptic brain that evolves slowly and differs fundamentally in well-controlled and poorly controlled epilepsy.
A subset of epilepsy cases of unknown etiology may be secondary to the production of autoantibodies.
Despite recommendations, many patients in the cohort were prescribed older antiepileptic drugs.
There are several drug-based and non-pharmacological treatments available that can help reduce symptoms of depression in patients with epilepsy.
Patients who participated in a group course with other people with epilepsy felt less isolated and more confident.
A diagnosis of maternal epilepsy alone was not associated with an increase in congenital malformations in offspring.
Quality improvement measures help to reduce emergency department visits, inpatient hospitalizations, and health care claims.
Patients with both MS and epileptic seizures had a younger age at onset of MS compared with those without seizures.
Functional MRI may provide a less-invasive option for evaluating memory function in patients undergoing epilepsy surgery.
Brain oxygenation may be compromised during periodic discharges, ultimately warranting treatment.
Nearly 60% of patients had achieved seizure freedom at last follow-up, 10 to 21 years after surgery.
Careful monitoring of EEG patterns is a useful way to stratify seizure risk in critically ill patients.
The results confirm the effectiveness and safety of low-dose CBZ as a first-line agent for the treatment of neonatal seizures.
Greater spasm cessation was achieved in the combination group vs those who received hormonal therapy alone.
Beate Diehl, MD, PhD, FRCP, discusses her research on post-stroke epilepsy.
Shaun Hussain, MD, MS, discusses a gap in health care provider knowledge that may contribute to the delay in the diagnosis and treatment of infantile spasms.
Elizabeth Thiele, MD, PhD discusses results from her research on cannabidiol in Lennox-Gastaut syndrome.
Clobazam had been previously identified as an AED with a significant interaction with CBD.
Justin Gover, CEO of GW Pharmaceuticals, the parent company of Greenwich Biosciences, discusses the status of the company's cannabidiol product Epidiolex on the heels of positive results from several placebo-controlled trials in epileptic syndromes.
Number of AEDs and seizure frequency also influenced depression in people with epilepsy.
Concordant EEG/fMRI and ESI predicted outcomes with 100% sensitivity and specificity.
Adjunctive everolimus treatment has been found to significantly reduce frequency of treatment-resistant seizures in TSC.
The triple-validated SeLECT score may help identify patients suited for antiepileptic drug trials.
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