Epilepsy

Should EEG Periodic Discharges be Managed Similarly to Seizures?

Should EEG Periodic Discharges be Managed Similarly to Seizures?

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Brain oxygenation may be compromised during periodic discharges, ultimately warranting treatment.

Seizure Reduction Likely With Surgery in Nonlesional Neocortical Epilepsy

Seizure Reduction Likely With Surgery in Nonlesional Neocortical Epilepsy

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Nearly 60% of patients had achieved seizure freedom at last follow-up, 10 to 21 years after surgery.

EEG Patterns in Critically Ill Point to Greater Risk of Seizures

EEG Patterns in Critically Ill Point to Greater Risk of Seizures

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Careful monitoring of EEG patterns is a useful way to stratify seizure risk in critically ill patients.

First-Line Treatment With Carbamazepine in Neonatal Epilepsy

First-Line Treatment With Carbamazepine in Neonatal Epilepsy

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The results confirm the effectiveness and safety of low-dose CBZ as a first-line agent for the treatment of neonatal seizures.

Vigabatrin Plus Hormonal Therapy Superior in Infantile Spasms

Vigabatrin Plus Hormonal Therapy Superior in Infantile Spasms

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Greater spasm cessation was achieved in the combination group vs those who received hormonal therapy alone.

VIDEO: Identifying Risk Factors for Post-Stroke Epilepsy

VIDEO: Identifying Risk Factors for Post-Stroke Epilepsy

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Beate Diehl, MD, PhD, FRCP, discusses her research on post-stroke epilepsy.

VIDEO: Gap in Provider Knowledge Delays Diagnosis, Treatment of Infantile Spasms

VIDEO: Gap in Provider Knowledge Delays Diagnosis, Treatment of Infantile Spasms

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Shaun Hussain, MD, MS, discusses a gap in health care provider knowledge that may contribute to the delay in the diagnosis and treatment of infantile spasms.

VIDEO: Elizabeth Thiele, MD, PhD Discusses Latest Cannabidiol Research

VIDEO: Elizabeth Thiele, MD, PhD Discusses Latest Cannabidiol Research

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Elizabeth Thiele, MD, PhD discusses results from her research on cannabidiol in Lennox-Gastaut syndrome.

Significant Drug-Drug Interactions With Cannabidiol and Antiepileptics

Significant Drug-Drug Interactions With Cannabidiol and Antiepileptics

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Clobazam had been previously identified as an AED with a significant interaction with CBD.

VIDEO — Industry Update: Justin Gover, CEO, GW Pharmaceuticals on Epidiolex Status

VIDEO — Industry Update: Justin Gover, CEO, GW Pharmaceuticals on Epidiolex Status

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Justin Gover, CEO of GW Pharmaceuticals, the parent company of Greenwich Biosciences, discusses the status of the company's cannabidiol product Epidiolex on the heels of positive results from several placebo-controlled trials in epileptic syndromes.

Social Support a Significant Factor in Development of Anxiety, Depression in Epilepsy

Social Support a Significant Factor in Development of Anxiety, Depression in Epilepsy

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Number of AEDs and seizure frequency also influenced depression in people with epilepsy.

Accurate Surgical Localization Using Combined Imaging Approach in Epilepsy

Accurate Surgical Localization Using Combined Imaging Approach in Epilepsy

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Concordant EEG/fMRI and ESI predicted outcomes with 100% sensitivity and specificity.

Factors Predictive of Everolimus Efficacy in Tuberous Sclerosis Complex

Factors Predictive of Everolimus Efficacy in Tuberous Sclerosis Complex

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Adjunctive everolimus treatment has been found to significantly reduce frequency of treatment-resistant seizures in TSC.

A Novel Risk Score for Seizures After Stroke

A Novel Risk Score for Seizures After Stroke

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The triple-validated SeLECT score may help identify patients suited for antiepileptic drug trials.

Cannabidiol Reduces Seizure Frequency in Refractory Dravet Syndrome

Cannabidiol Reduces Seizure Frequency in Refractory Dravet Syndrome

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Results of the phase 3, placebo-controlled trial support previous findings from an expanded-access program.

Brain Atrophy May Help Predict Surgical Outcomes in Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis

Brain Atrophy May Help Predict Surgical Outcomes in Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis

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Atrophy in areas outside of the MTLE-HS network may predict poor surgical outcomes.

Major Provider Knowledge Gap Delays Diagnosis, Treatment of Infantile Spasms

Major Provider Knowledge Gap Delays Diagnosis, Treatment of Infantile Spasms

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Less than 30% of patients were seen by an effective provider within 1 week of onset of infantile spasms.

Potential Reduction in Seizure Frequency With Statin Therapy

Potential Reduction in Seizure Frequency With Statin Therapy

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Half of patients experienced a reduction in seizure frequency after statin initiation.

Polypharmacy Alone Worsens Quality of Life in Epilepsy

Polypharmacy Alone Worsens Quality of Life in Epilepsy

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Awareness of the effects of polypharmacy on patient well-being is an important component of care.

Cannabidiol Helps Reduce Frequency of Drop Seizures in Lennox-Gastaut Syndrome

Cannabidiol Helps Reduce Frequency of Drop Seizures in Lennox-Gastaut Syndrome

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Patients taking cannabidiol experienced a significant reduction in drop seizures compared with placebo.

Age, Lesion Volume Influence Epilepsy Risk After Stroke

Age, Lesion Volume Influence Epilepsy Risk After Stroke

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Patients with lesions in the left basal ganglia were more likely to have post-stroke epilepsy.

What to Expect at the 2016 American Epilepsy Society Annual Meeting

What to Expect at the 2016 American Epilepsy Society Annual Meeting

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Michael Privatera, MD, AES president spoke with Neurology Advisor about some of the key topics and presentations slated for this year's meeting.

Increased Physical, Mental Comorbidity in Veterans With Epilepsy

Increased Physical, Mental Comorbidity in Veterans With Epilepsy

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Veterans with epilepsy could benefit from evidence-based chronic disease self-management programs that target physical and psychiatric comorbidities.

Deviations From Recommended Care in Pediatric Seizure

Deviations From Recommended Care in Pediatric Seizure

Lack of adherence has been linked to increased risks of intubation and ICU admission.

Parental Rheumatoid Arthritis and Risk for Epilepsy in Offspring

Parental Rheumatoid Arthritis and Risk for Epilepsy in Offspring

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Data suggests that epileptogenic mechanisms may be triggered by changes in the intrauterine environment during pregnancy in women with RA.

Left Temporal Lobe Resection Linked to Naming Decline in Refractory Epilepsy

Left Temporal Lobe Resection Linked to Naming Decline in Refractory Epilepsy

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Those with older age at seizure onset are at the greatest risk for decline in naming ability.

VIDEO: Cannabidiol and Our Progress Towards a Treatment for Refractory Epilepsy

VIDEO: Cannabidiol and Our Progress Towards a Treatment for Refractory Epilepsy

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Dr Elizabeth Thiele discusses the latest on cannabidiol research for the treatment of refractory epilepsy.

Spike Localization May Predict Cognitive Outcomes in BECTS

Spike Localization May Predict Cognitive Outcomes in BECTS

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Patients with these EEG characteristics may benefit from early screening and intervention.

Everolimus Safe, Effective for Reduction of Seizures in Tuberous Sclerosis Complex

Everolimus Safe, Effective for Reduction of Seizures in Tuberous Sclerosis Complex

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The EXIST-3 trial is the first phase 3 study to evaluate the use of EVE for the adjunctive treatment of seizures in TSC.

Executive Dysfunction in Epilepsy-associated Depression

Executive Dysfunction in Epilepsy-associated Depression

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Those suffering from depression and those diagnosed with temporal lobe epilepsy present with dysfunction across several cognitive domains.

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