General Neurology

Diagnosing Tuberculous Meningitis: Overcoming Challenges

Diagnosing Tuberculous Meningitis: Overcoming Challenges

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Diagnosis of TB meningitis is challenging, although new, next-generation rapid POC testing holds promise for greatly improved sensitivity.

West Nile Virus Linked to Neurologic Abnormalities

West Nile Virus Linked to Neurologic Abnormalities

Abnormalities on neurologic examination were found several years after patients were infected with West Nile virus.

Altered Hemodynamics May Influence White Matter Hyperintensity Development

Altered Hemodynamics May Influence White Matter Hyperintensity Development

There was a linear link between white matter hyperintensity volume and RA pressure in chronic valvular heart disease.

Development of Guillain-Barré Syndrome Associated With Zika Virus Infection

Development of Guillain-Barré Syndrome Associated With Zika Virus Infection

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Infection with the Zika virus may increase the risk for development of Guillain-Barré syndrome.

Publication Bias in Neurology Research: Why It Matters and Why It Needs to Change

Publication Bias in Neurology Research: Why It Matters and Why It Needs to Change

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Withholding negative research results not only skews scientific evidence but also puts into question the whole validity of medical research.

Functional Brain Connectivity Has Familial, Heritable Patterns

Functional Brain Connectivity Has Familial, Heritable Patterns

The findings may help to better characterize normative development and altered patterns of brain activity that may serve as biomarkers for neurological conditions.

Immunosuppressive Therapies May Reduce Relapse in Neurosarcoidosis

Immunosuppressive Therapies May Reduce Relapse in Neurosarcoidosis

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Although some patients will recover completely after corticosteroid therapy, some will experience multiple relapses and develop related severe functional impairments.

Recreational Amphetamine Use Underreported in Teens

Recreational Amphetamine Use Underreported in Teens

Adolescents seem to be unaware that Adderall is an amphetamine, therefore they underrort their nonmedical amphetamine use.

Unsafe Drinking Water: Your Role as a Clinician

Unsafe Drinking Water: Your Role as a Clinician

Most physicians in Flint were not trained in advocacy or leadership and had not received formal environmental health training.

Infective Endocarditis: Best Practices for Treating Neurologic Complications

Infective Endocarditis: Best Practices for Treating Neurologic Complications

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Ischemic and hemorrhagic strokes are a common complication of infective endocarditis, but guidance on intervention is varied.

Key Metrics for Defining Optimal Brain Health in Adults: AHA/ASA Guidance

Key Metrics for Defining Optimal Brain Health in Adults: AHA/ASA Guidance

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The American Heart and American Stroke Associations have developed an outline focused on the impact of cognitive impairment on public health, and the maintenance and definition of optimal brain health.

Tau Predicts Neurological Outcomes After Cardiac Arrest

Tau Predicts Neurological Outcomes After Cardiac Arrest

Serum tau is a promising novel biomarker for prediction of neurological outcome in patients with cardiac arrest.

Anesthesia and Long-Term Cognitive Decline: Is There a Link?

Anesthesia and Long-Term Cognitive Decline: Is There a Link?

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Findings from animal studies indicate that anesthetics may be neurotoxic and could result in long-term central nervous system alterations and cognitive dysfunction.

Mental Health Treatment Deficit Among Physicians

Mental Health Treatment Deficit Among Physicians

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Due to physician licensing, physicians may not be seeking treatment for mental health issues.

Characteristics of Neurotoxicity After CD19 CAR-T Cell Infusion

Characteristics of Neurotoxicity After CD19 CAR-T Cell Infusion

Patients with severe neurotoxicity have evidence of endothelial activation.

Tinnitus Associated With Medial Temporal Lobe Surgery

Tinnitus Associated With Medial Temporal Lobe Surgery

There is an increased prevalence of tinnitus in patients undergoing medial temporal lobe surgery.

Gabapentin Effective for Vagal Neuropathy-Related Chronic Cough

Gabapentin Effective for Vagal Neuropathy-Related Chronic Cough

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The presence of vocal fold motion asymmetry may be used to make more informed clinical decisions for treatment.

Test to Detect Zika Virus in Blood Donations Approved

Test to Detect Zika Virus in Blood Donations Approved

The test is not designed to diagnose an individual's infection, however.

Increased Anesthesia Duration Linked to Post-Op Complications

Increased Anesthesia Duration Linked to Post-Op Complications

Researchers from Rutgers New Jersey Medical School investigated the duration of anesthesia and the risk of post operative complications associated.

Expensive Drugs Produce Stronger Nocebo Effect

Expensive Drugs Produce Stronger Nocebo Effect

Nocebo hyperalgesia was stronger when the treatment was labeled as an expensive medication versus a cheap medication

Support Growing for Genome Editing for Disease Prevention

Support Growing for Genome Editing for Disease Prevention

Somatic genome editing for prevention of serious disease is supported by scientists and clinical researchers.

The Factor That Made Zika a Mega-Outbreak

The Factor That Made Zika a Mega-Outbreak

The increased incidence of microcephaly was caused by a single mutation in the Zika virus.

Seizures More Likely in Patients With Sepsis Than General Population

Seizures More Likely in Patients With Sepsis Than General Population

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Patients with sepsis included in this analysis may have presented with other CNS pathologies that could have contributed to seizure risk.

Neurostimulation Provides Abdominal Pain Relief in Children

Neurostimulation Provides Abdominal Pain Relief in Children

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Neurostimulation through percutaneous electrical nerve field stimulation was shown to durably reduce pain in children.

PD-1 Therapy for Cancer Increases Risk for Neurological Complications

PD-1 Therapy for Cancer Increases Risk for Neurological Complications

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The clinical spectrum and optimal treatment approach for PD-1-related neurological complications is not clear.

Zika Virus Associated With High Risk for Neurologic Complications in Adults

Zika Virus Associated With High Risk for Neurologic Complications in Adults

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Rates of neurologic complications increased in the months after the Zika virus outbreak in Brazil.

Lower Systolic Blood Pressure Targets May Benefit Cognition in Black Patients

Lower Systolic Blood Pressure Targets May Benefit Cognition in Black Patients

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Findings from this trial challenge current recommended systolic blood pressure targets for older adults.

No Association Between Cardiovascular Drugs and Cognitive Impairment

No Association Between Cardiovascular Drugs and Cognitive Impairment

There is no association between use of cardiovascular medication and cognitive impairment in older adults.

No Neurologic Benefit for Longer Temperature Management After Cardiac Arrest

No Neurologic Benefit for Longer Temperature Management After Cardiac Arrest

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Further research in a larger cohort may be required to detect any changes in treatment effect in this patient group.

Zika Thrives in Pregnancy Due to Weak Immune System

Zika Thrives in Pregnancy Due to Weak Immune System

The Zika virus thrives in pregnant women because of their already dampened immune system.

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