Migraine And Headache

Fremanezumab Linked to Fewer Monthly Migraine Days

Fremanezumab Linked to Fewer Monthly Migraine Days

For patients with episodic migraine, fremanezumab is associated with a reduction in the mean number of monthly migraine days.

Galcanezumab Effective in Phase 3 Episodic Cluster Headache Study

Galcanezumab Effective in Phase 3 Episodic Cluster Headache Study

By

The episodic cluster headache trial included a total of 106 patients with an average of 17.5 cluster headache attacks per week at baseline.

Antidepressant Medications and Headache: Is There a Link?

Antidepressant Medications and Headache: Is There a Link?

By

Compared to placebo, selective serotonin reuptake inhibitors (SSRIs) were associated with a significantly higher risk of headache (risk ratio [RR] 1.06, 95% CI: 1.00 to 1.13; P =.045).

Results From Phase 3 Trial of Migraine Tx Ubrogepant Released

Results From Phase 3 Trial of Migraine Tx Ubrogepant Released

By

Allergan announced results from the second Phase 3 trial for their novel acute migraine treatment, ubrogepant.

Pain, Psychiatric Comorbidities More Common in Chronic vs Episodic Migraine

Pain, Psychiatric Comorbidities More Common in Chronic vs Episodic Migraine

By

Individuals with chronic vs episodic migraine may be more likely to experience chronic back pain, chronic pain, neck pain, anxiety, and depression.

New Zolmitriptan Intracutaneous System Safe and Effective for Migraine

New Zolmitriptan Intracutaneous System Safe and Effective for Migraine

By

Researchers conducted a randomized, double-blond, placebo-controlled, dose-ranging trial to assess the use of a new zolmitriptan intracutaneous delivery system in adults with migraine headache.

Erenumab Shown to Reduce Headache Days for Patients with Episodic Migraine

Erenumab Shown to Reduce Headache Days for Patients with Episodic Migraine

By

Researchers assessed the ability of erenumab to decrease the mean number of acute headache days in patients with episodic migraine.

Comorbidity More Likely With Chronic Migraine vs Episodic Migraine

Comorbidity More Likely With Chronic Migraine vs Episodic Migraine

By

Researchers deployed a survey to determine the extent of pain, psychiatric, endocrine, and neurologic comorbidities in patients with chronic or episodic migraine.

Eptinezumab for Frequent Episodic Migraine: Results of Phase 3 PROMISE-1 Study

Eptinezumab for Frequent Episodic Migraine: Results of Phase 3 PROMISE-1 Study

By

Eptinezumab, a humanized monoclonal antibody specific to calcitonin gene-related peptide, may be an effective prophylactic for individuals with frequent episodic migraines.

Patient Develops Thunderclap Headaches After Consuming 'Carolina Reaper'

Patient Develops Thunderclap Headaches After Consuming 'Carolina Reaper'

By

The authors note that this appears to be the first case of RCVS secondary to pepper or cayenne ingestion.

Noninvasive Brain Stimulation May Help Prevent Migraines

Noninvasive Brain Stimulation May Help Prevent Migraines

Single-pulse transcranial magnetic stimulation device is safe and easy to use.

Novel Nasal Spray for Migraine Attacks to Be FDA Reviewed

Novel Nasal Spray for Migraine Attacks to Be FDA Reviewed

By

DFN-02 was evaluated in a multicenter, double-blind, randomized, placebo-controlled study (N=107) which showed it was effective in treating pain and associated symptoms during a migraine attack and in reducing attack-related functional disability.

Sumatriptan Self-Injection System No Longer Available

Sumatriptan Self-Injection System No Longer Available

By

Sumavel DosePro for the treatment of migraine or cluster headache has been discontinued.

Erenumab for Episodic Migraine: A Closer Look at the Data

Erenumab for Episodic Migraine: A Closer Look at the Data

By

For individuals with migraine frequency of 4 to 14 episodes per month, prophylactic medications and analgesics are required.

Ubrogepant Effective for Acute Migraine Relief

Ubrogepant Effective for Acute Migraine Relief

By

Allergan has reported positive results from the first of 2 Phase 3 trials for ubrogepant for the treatment of migraine.

GammaCore Approved for Treatment of Acute Migraine Pain

GammaCore Approved for Treatment of Acute Migraine Pain

By

The FDA has granted GammaCore 510(k) expanded clearance to treat migraine related pain.

Refractory Migraine Effectively Treated With Erenumab

Refractory Migraine Effectively Treated With Erenumab

By

Amgen announced that erenumab met its primary endpoint in reducing monthly migraine days.

Migraine, Tension-Type Headache Likely After Exposure to Violence

Migraine, Tension-Type Headache Likely After Exposure to Violence

By

Prior physical or sexual abuse of survivors increased the likelihood of migraine or tension-type headache.

Coping Questionnaire Helps Assess Migraine Pain

Coping Questionnaire Helps Assess Migraine Pain

The PSEQ successfully shows the debility in migraine surgery patients, and puts migraine pain to perspective.

Migraine Risk Significantly Reduced With Investigational Drug

Migraine Risk Significantly Reduced With Investigational Drug

By

Patients were randomly assigned to receive eptinezumab (300mg or 100mg) or placebo once every 12 weeks.

Early Treatment, Milder Migraine Symptoms Linked to Improved Outcomes With OnabotulinumtoxinA

Early Treatment, Milder Migraine Symptoms Linked to Improved Outcomes With OnabotulinumtoxinA

By

For patients with chronic migraine, onabotulinumtoxinA was shown to have a better outcome.

Migraine Resolves With Antiviral, NSAID Drug Combo: Case Report

Migraine Resolves With Antiviral, NSAID Drug Combo: Case Report

By

In a case report, a 21 year old female's migraine was successfully treated with therapy specifically aimed at the herpes simplex virus.

Weight Loss, Migraine Education Have Similar Effect on Migraine Reduction

Weight Loss, Migraine Education Have Similar Effect on Migraine Reduction

By

Researchers report that a behavioral weight loss program may be effective in reducing migraine headaches as social support from a group of people facing similar circumstances may help patients cope.

Caffeine as Headache Trigger and Treatment: Two Sides of the Same Coin

Caffeine as Headache Trigger and Treatment: Two Sides of the Same Coin

By

The judicious use of caffeine as adjuvant therapy to over-the-counter pain relievers can improve or relieve pain for patients with migraine or tension-type headaches.

Reducing Stroke Risk in Women With Migraine Receiving Hormonal Contraceptives: Consensus Statement

Reducing Stroke Risk in Women With Migraine Receiving Hormonal Contraceptives: Consensus Statement

By

Women with migraine should avoid high-risk products such as combined oral HCs consisting of >35μg ethinylestradiol.

FDA Will Review Injectable Migraine Prevention Treatment

FDA Will Review Injectable Migraine Prevention Treatment

By

The FDA has accepted a BLA for the migraine prevention treatment, galcanezumab.

Patients With Migraine Often Return to the Emergency Department

Patients With Migraine Often Return to the Emergency Department

By

Over 25% of patients who end up in the emergency department for migraine typically require revisits for headache within 6 months.

Magnesium May Be Effective for Migraine Prophylaxis

Magnesium May Be Effective for Migraine Prophylaxis

By

The review suggests that magnesium is a safe, tolerable, and cost-effective treatment for migraine.

Higher Stroke Risk Associated With Estrogen Contraceptives in Women With Migraine

Higher Stroke Risk Associated With Estrogen Contraceptives in Women With Migraine

By

A systematic review aimed to validate whether stroke risk is increased in women taking estrogen-containing contraceptives who have a history of migraine.

Devices for Acute, Preventive Migraine Care Now Available

Devices for Acute, Preventive Migraine Care Now Available

By

Cefaly Acute and Cefaly Dual were approved for treating migraines.

Sign Up for Free e-newsletters

CME Focus