Movement Disorders Headlines

Movement Disorders Patients With Parkinson Disease Are at High Risk for Depression

Patients With Parkinson Disease Are at High Risk for Depression

Female sex, dependency, high pain scores, and lower Mini-Mental State Examination scores were correlated with higher depression scores.

Movement Disorders Drug May Help Improve Daytime Sleepiness in Parkinson's

Drug May Help Improve Daytime Sleepiness in Parkinson's

Sodium oxybate seems to be effective for patients with Parkinson disease and excessive daytime sleepiness.

Movement Disorders Orphan Drug Designation Granted to Valbenazine for Tourette Syndrome

Orphan Drug Designation Granted to Valbenazine for Tourette Syndrome

The primary endpoint of the study is the change from baseline of the Yale Global Tic Severity Scale between placebo and active treatment groups at the end of week 12.

Movement Disorders Asleep Deep Brain Stimulation Linked to Better Outcomes in Parkinson's

Asleep Deep Brain Stimulation Linked to Better Outcomes in Parkinson's

Deep brain stimulation is traditionally conducted with the patient awake in order to help the ideal target for electrode placement.

Movement Disorders Smoking Modifies Genetic Link to Parkinson Disease

Smoking Modifies Genetic Link to Parkinson Disease

Smoking may modify a genetic link with Parkinson disease.

Movement Disorders Little Evidence Supports CSF α-Synuclein as a Diagnostic Tool for Parkinson Disease

Little Evidence Supports CSF α-Synuclein as a Diagnostic Tool for Parkinson Disease

The diagnosis of Parkinson disease is made mostly through a clinical assessment of motor signs and symptoms, which appear when approximately 70% of nigral neurons are lost.

Movement Disorders AbobotulinumtoxinA Beneficial for Children With Lower Limb Spasticity

AbobotulinumtoxinA Beneficial for Children With Lower Limb Spasticity

Significant improvements in muscle tone, spasticity, goal attainment, and overall clinical benefit were observed across all injection cycles.

Movement Disorders Compulsive Behavior Disorders Common in Patients With Parkinson Disease With Dyskinesia

Compulsive Behavior Disorders Common in Patients With Parkinson Disease With Dyskinesia

Patients with dyskinesia had a significantly higher frequency of impulse control disorders.

Movement Disorders Prognostic Models for Predicting Death and Dependency in Parkinson's

Prognostic Models for Predicting Death and Dependency in Parkinson's

The investigators suggested that the models should be recalibrated based on geographic location for more individualized predictions.

Movement Disorders Parkinsonism Diagnosis Linked to Cognitive Deficits

Parkinsonism Diagnosis Linked to Cognitive Deficits

Cognitive dysfunction may be a sign of prodromal Parkinson disease.

Movement Disorders New Dose Approved for Tardive Dyskinesia Drug Ingrezza

New Dose Approved for Tardive Dyskinesia Drug Ingrezza

Ingrezza is a vesicular monoamine transporter 2 inhibitor, now available in an 80mg capsule.

Movement Disorders Cycling Overloads Movement Networks Impacted by Parkinson Disease

Cycling Overloads Movement Networks Impacted by Parkinson Disease

Abnormal beta synchrony in the Parkinsonian basal ganglia is suppressed by bicycling.

Movement Disorders Parkinson Drugs With Highest Adverse Effect Rates

Parkinson Drugs With Highest Adverse Effect Rates

The highest incidence rates of adverse effects in PD were linked with ropinirole, bromocriptine, and piribedil.

Movement Disorders Increased Parkinson's Risk Associated With Poor Sense of Smell

Increased Parkinson's Risk Associated With Poor Sense of Smell

A poor sense of smell is linked with an increased risk for Parkinson's disease.

Movement Disorders β-2 Adrenergic Agonists Linked to α-synuclein Transcription and Risk of PD

β-2 Adrenergic Agonists Linked to α-synuclein Transcription and Risk of PD

β-2 adrenergic agonists might be able to fight Parkinson's disease.

Movement Disorders Cerebellar Deficit in Dystonia Improved With Alcohol

Cerebellar Deficit in Dystonia Improved With Alcohol

Alcohol improves cerebellar-learning deficit in patients with myoclonus-dystonia.

Movement Disorders Parkinson's: Sleep Disturbances Affect Clinical Motor Subtypes, Disability

Parkinson's: Sleep Disturbances Affect Clinical Motor Subtypes, Disability

Patients with postural instability and gait disturbances had worse sleep scores than those with tremor-dominant Parkinson's.

Movement Disorders Increased Mortality in Parkinson's Disease Linked to Low Antidepressant Adherence

Increased Mortality in Parkinson's Disease Linked to Low Antidepressant Adherence

Given the prevalence of depression in Parkinson's disease and the effectiveness of antidepressants, health care providers should promote adherence in clinical practice.

Movement Disorders Age, Gender, and Cognition Predict Weight Loss in Parkinson's Disease

Age, Gender, and Cognition Predict Weight Loss in Parkinson's Disease

Enrollment of patients with only early Parkinson's disease in this trial prevents generalization of the study's findings across the entire Parkinson's population.

Movement Disorders Parkinson's, REM Sleep Disorder Combination Linked to Cognitive Decline

Parkinson's, REM Sleep Disorder Combination Linked to Cognitive Decline

Patients with both Parkinson's and rapid eye movement sleep behavior disorder were much more likely to experience mild cognitive impairment.

Sign Up for Free e-newsletters

CME Focus