Movement Disorders Headlines
Female sex, dependency, high pain scores, and lower Mini-Mental State Examination scores were correlated with higher depression scores.
Sodium oxybate seems to be effective for patients with Parkinson disease and excessive daytime sleepiness.
The primary endpoint of the study is the change from baseline of the Yale Global Tic Severity Scale between placebo and active treatment groups at the end of week 12.
Deep brain stimulation is traditionally conducted with the patient awake in order to help the ideal target for electrode placement.
Smoking may modify a genetic link with Parkinson disease.
The diagnosis of Parkinson disease is made mostly through a clinical assessment of motor signs and symptoms, which appear when approximately 70% of nigral neurons are lost.
Significant improvements in muscle tone, spasticity, goal attainment, and overall clinical benefit were observed across all injection cycles.
Patients with dyskinesia had a significantly higher frequency of impulse control disorders.
The investigators suggested that the models should be recalibrated based on geographic location for more individualized predictions.
Cognitive dysfunction may be a sign of prodromal Parkinson disease.
Ingrezza is a vesicular monoamine transporter 2 inhibitor, now available in an 80mg capsule.
Abnormal beta synchrony in the Parkinsonian basal ganglia is suppressed by bicycling.
The highest incidence rates of adverse effects in PD were linked with ropinirole, bromocriptine, and piribedil.
A poor sense of smell is linked with an increased risk for Parkinson's disease.
β-2 adrenergic agonists might be able to fight Parkinson's disease.
Alcohol improves cerebellar-learning deficit in patients with myoclonus-dystonia.
Patients with postural instability and gait disturbances had worse sleep scores than those with tremor-dominant Parkinson's.
Given the prevalence of depression in Parkinson's disease and the effectiveness of antidepressants, health care providers should promote adherence in clinical practice.
Enrollment of patients with only early Parkinson's disease in this trial prevents generalization of the study's findings across the entire Parkinson's population.
Patients with both Parkinson's and rapid eye movement sleep behavior disorder were much more likely to experience mild cognitive impairment.
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