Movement Disorders Headlines
Despite evidence suggesting there is an impact of physical activity and body mass index on the risk for Parkinson disease, a large prospective study published in Neurology shows that there is no significant association between prolonged sitting/inactivity or obesity with PD risk.
Patients with TBI had a higher incidence of PD compared with patients without TBI.
Using information from these assessments, investigators identified participants as having either major psychotic symptoms, isolated minor psychotic symptoms, or no psychotic symptoms.
Lightning, which can result in strong electromagnetic fields, can interfere with deep brain stimulation devices.
Risk factors for all study participants were calculated on the basis of the following factors known to be previously linked to PD risk: total caffeine intake, smoking, physical activity, and family history of PD.
The assessment of psychiatric symptoms relied on only one question in the MDS-UPDRS, potentially leading to underestimation of these symptoms in this cohort.
Patients with IBD who were exposed to anti-TNF therapy had a significant decrease in incidence of PD.
Non-invasive neuromodulation therapy using a custom stimulation pattern provides symptomatic relief from hand tremor in essential tremor.
Concerns over Nuplazid were initially voiced in a CNN article in early April which reported that the drug had been associated with over 700 deaths since its launch in March 2017.
Previous research has suggested a genetic and functional link between IBD and PD, however evidence regarding this association has been limited.
Mild traumatic brain injury is associated with increased risk of Parkinson disease among military veterans.
By 2 years, 30% of patients had increased their levodopa dose by ~300mg, indicating that treatment with Gocovri may allow for further levodopa optimization despite the occurrence of dyskinesia.
Investigators conducted a review of electronic medical records to assess functional neurologic disorders in patients with Parkinson disease.
Wearable technology may help monitor on/off states in patients with Parkinson disease in an outpatient setting.
Researchers sought to assess outcomes in hospitalized patients with comorbid Parkinson disease and major depressive disorder following administration of deep brain stimulation.
Researchers found that for men with any occupational exposure to diesel exhaust, the odds ratio for amyotrophic lateral sclerosis increased with increasing lag periods.
Researchers say that tears may be an inexpensive, reliable, and noninvasive biological marker of Parkinson's disease.
Approximately 20% of patients in this cohort were considered clinically depressed based on GDS criteria.
Demoralization is common in patients with Parkinson disease and is associated with motor dysfunction.
ADS-5102 is a promising treatment option: if taken once daily at night, it achieves highest plasma drug concentrations throughout the day when symptoms are most bothersome.
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