Movement Disorders Headlines

Movement Disorders Inactivity, Obesity Exert No Significant Influence on Parkinson Disease Risk

Inactivity, Obesity Exert No Significant Influence on Parkinson Disease Risk

Despite evidence suggesting there is an impact of physical activity and body mass index on the risk for Parkinson disease, a large prospective study published in Neurology shows that there is no significant association between prolonged sitting/inactivity or obesity with PD risk.

Traumatic Brain Injury Traumatic Brain Injury Linked to Increased Parkinson Disease Risk in Veterans

Traumatic Brain Injury Linked to Increased Parkinson Disease Risk in Veterans

Patients with TBI had a higher incidence of PD compared with patients without TBI.

Movement Disorders Enhanced Scale Helps Accurately Identify Psychotic Symptoms in Parkinson Disease

Enhanced Scale Helps Accurately Identify Psychotic Symptoms in Parkinson Disease

Using information from these assessments, investigators identified participants as having either major psychotic symptoms, isolated minor psychotic symptoms, or no psychotic symptoms.

General Neurology Lightning Can Affect Deep Brain Stimulation Devices

Lightning Can Affect Deep Brain Stimulation Devices

Lightning, which can result in strong electromagnetic fields, can interfere with deep brain stimulation devices.

Movement Disorders Lifestyle Factors, Family History Linked to Overall Risk for Parkinson Disease

Lifestyle Factors, Family History Linked to Overall Risk for Parkinson Disease

Risk factors for all study participants were calculated on the basis of the following factors known to be previously linked to PD risk: total caffeine intake, smoking, physical activity, and family history of PD.

Movement Disorders Factors Associated With Long-Term Psychotic Symptoms in Parkinson's

Factors Associated With Long-Term Psychotic Symptoms in Parkinson's

The assessment of psychiatric symptoms relied on only one question in the MDS-UPDRS, potentially leading to underestimation of these symptoms in this cohort.

Movement Disorders IBD Associated With Increased Incidence of Parkinson Disease

IBD Associated With Increased Incidence of Parkinson Disease

Patients with IBD who were exposed to anti-TNF therapy had a significant decrease in incidence of PD.

AAN 2018 Coverage Neuromodulation Therapy Gives Relief From Hand Tremor

Neuromodulation Therapy Gives Relief From Hand Tremor

Non-invasive neuromodulation therapy using a custom stimulation pattern provides symptomatic relief from hand tremor in essential tremor.

Movement Disorders Acadia Addresses Concerns Over Nuplazid Safety in Parkinson Disease Patients

Acadia Addresses Concerns Over Nuplazid Safety in Parkinson Disease Patients

Concerns over Nuplazid were initially voiced in a CNN article in early April which reported that the drug had been associated with over 700 deaths since its launch in March 2017.

Movement Disorders Exposure to Anti-TNF Therapy Linked to Reduced Parkinson Disease Risk

Exposure to Anti-TNF Therapy Linked to Reduced Parkinson Disease Risk

Previous research has suggested a genetic and functional link between IBD and PD, however evidence regarding this association has been limited.

Traumatic Brain Injury Mild TBI May Increase Risk of Parkinson Disease

Mild TBI May Increase Risk of Parkinson Disease

Mild traumatic brain injury is associated with increased risk of Parkinson disease among military veterans.

Movement Disorders Long-Term Benefits of Gocovri Observed in PD Patients With Dyskinesia

Long-Term Benefits of Gocovri Observed in PD Patients With Dyskinesia

By 2 years, 30% of patients had increased their levodopa dose by ~300mg, indicating that treatment with Gocovri may allow for further levodopa optimization despite the occurrence of dyskinesia.

Movement Disorders Dyskinesia, Psychiatric Disorders Associated With Functional Neurological Symptoms in PD

Dyskinesia, Psychiatric Disorders Associated With Functional Neurological Symptoms in PD

Investigators conducted a review of electronic medical records to assess functional neurologic disorders in patients with Parkinson disease.

AAN 2018 Coverage Wearable Sensors May Help Predict On, Off States in Parkinson Disease

Wearable Sensors May Help Predict On, Off States in Parkinson Disease

Wearable technology may help monitor on/off states in patients with Parkinson disease in an outpatient setting.

AAN 2018 Coverage DBS Improves Inpatient Outcomes for Comorbid Parkinson Disease and Depression

DBS Improves Inpatient Outcomes for Comorbid Parkinson Disease and Depression

Researchers sought to assess outcomes in hospitalized patients with comorbid Parkinson disease and major depressive disorder following administration of deep brain stimulation.

AAN 2018 Coverage Occupational Exposure to Diesel Exhaust Tied to ALS Risk

Occupational Exposure to Diesel Exhaust Tied to ALS Risk

Researchers found that for men with any occupational exposure to diesel exhaust, the odds ratio for amyotrophic lateral sclerosis increased with increasing lag periods.

AAN 2018 Coverage Alpha-Synuclein Levels in Tears May Help ID Parkinson's

Alpha-Synuclein Levels in Tears May Help ID Parkinson's

Researchers say that tears may be an inexpensive, reliable, and noninvasive biological marker of Parkinson's disease.

Movement Disorders Connection Between Essential Tremor, Depression Remains Unclear

Connection Between Essential Tremor, Depression Remains Unclear

Approximately 20% of patients in this cohort were considered clinically depressed based on GDS criteria.

Movement Disorders Demoralization Common in Patients With Parkinson Disease

Demoralization Common in Patients With Parkinson Disease

Demoralization is common in patients with Parkinson disease and is associated with motor dysfunction.

Movement Disorders Extended Release Amantadine Effective for Reducing Dyskinesia in Parkinson Disease

Extended Release Amantadine Effective for Reducing Dyskinesia in Parkinson Disease

ADS-5102 is a promising treatment option: if taken once daily at night, it achieves highest plasma drug concentrations throughout the day when symptoms are most bothersome.

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