Movement Disorders

Featured Article

Cognitive Impairment in Multi-System Atrophy: Is It Time to Update Diagnostic Criteria?

Cognitive Impairment in Multi-System Atrophy: Is It Time to Update Diagnostic Criteria?

Although evidence of cognitive impairment in MSA is admittedly more limited than in Parkinson disease, it is now substantial enough to address modification of diagnostic criteria to include the potential for cognitive impairment at any stage of the disease.

Latest

Reports of Agranulocytosis Prompt Monitoring for Investigational Parkinson's Drug

Reports of Agranulocytosis Prompt Monitoring for Investigational Parkinson's Drug

Tozadenant is being investigated as an adjunctive treatment to levodopa in Parkinson disease patients to reduce 'off' time.

Parkinson Disease Onset Linked to LRRK2 Variants

Parkinson Disease Onset Linked to LRRK2 Variants

There is a younger age at onset of Parkinson disease linked with the presence of LRRK2 risk variants.

Patients With Parkinson Disease Are at High Risk for Depression

Patients With Parkinson Disease Are at High Risk for Depression

Female sex, dependency, high pain scores, and lower Mini-Mental State Examination scores were correlated with higher depression scores.

Drug May Help Improve Daytime Sleepiness in Parkinson's

Drug May Help Improve Daytime Sleepiness in Parkinson's

Sodium oxybate seems to be effective for patients with Parkinson disease and excessive daytime sleepiness.

Orphan Drug Designation Granted to Valbenazine for Tourette Syndrome

Orphan Drug Designation Granted to Valbenazine for Tourette Syndrome

The primary endpoint of the study is the change from baseline of the Yale Global Tic Severity Scale between placebo and active treatment groups at the end of week 12.

Asleep Deep Brain Stimulation Linked to Better Outcomes in Parkinson's

Asleep Deep Brain Stimulation Linked to Better Outcomes in Parkinson's

Deep brain stimulation is traditionally conducted with the patient awake in order to help the ideal target for electrode placement.

Smoking Modifies Genetic Link to Parkinson Disease

Smoking Modifies Genetic Link to Parkinson Disease

Smoking may modify a genetic link with Parkinson disease.

Little Evidence Supports CSF α-Synuclein as a Diagnostic Tool for Parkinson Disease

Little Evidence Supports CSF α-Synuclein as a Diagnostic Tool for Parkinson Disease

The diagnosis of Parkinson disease is made mostly through a clinical assessment of motor signs and symptoms, which appear when approximately 70% of nigral neurons are lost.

AbobotulinumtoxinA Beneficial for Children With Lower Limb Spasticity

AbobotulinumtoxinA Beneficial for Children With Lower Limb Spasticity

Significant improvements in muscle tone, spasticity, goal attainment, and overall clinical benefit were observed across all injection cycles.

Compulsive Behavior Disorders Common in Patients With Parkinson Disease With Dyskinesia

Compulsive Behavior Disorders Common in Patients With Parkinson Disease With Dyskinesia

Patients with dyskinesia had a significantly higher frequency of impulse control disorders.

Sign Up for Free e-newsletters

CME Focus