Dopamine deficiency, decreases in cortical thickness and volume in certain areas of the brain was predictive of cognitive decline.
Patients in the treatment group had improved ON and OFF times and no worsening of motor function.
Investigators examined blood plasma samples taken annually from a cohort of 201 huntingtin gene (HTT) carriers.
Investigators identified a series of prodromal signs that appear anywhere from 1 to 18 years before a clinical diagnosis of SCA2.
Patients with multiple system atrophy with parkinsonism face the greatest risk for death among synucleinopathies.
However, there is a trend toward lower risk of Parkinson's for patients with truncal vagotomy.
MRI-guided focused ultrasound thalamotomy is more effective than deep brain stimulation and significantly cheaper.
Electroconvulsive therapy might be safe and reliable therapy for treatment of psychiatric symptoms in patients with Huntington Disease
Long-term valbenazine may be beneficial in managing tardive dyskinesia in schizophrenia.
Learn more about what to expect from this year's International Congress of Parkinson's Disease and Movement Disorders.
Joohi Jimenez-Shahed, MD, discusses her research on the use of deutetrabenazine for the treatment of tardive dyskinesia in patients taking concomitant antipsychotics or neuroleptics. Scroll below the video for the full transcript.
New guidelines for progressive supranuclear palsy provide very specific and sensitive criteria that allow for identification of clinical features of the disease at much earlier stages.
Dextromethorphan is thought to have an impact on all 3 therapeutic pathways for dyskinesia.
Jori Fleisher, MD, MSCE, of New York University School of Medicine, discusses her research on an interdisciplinary home visit program for patients with advanced Parkinson's disease. Scroll below the video for the full transcript.
De novo likely gene disrupting variants were highly overrepresented in the Tourette's cases compared with unaffected parent and sibling sample controls.
The results add to the growing body of evidence in support of deep brain stimulation for refractory Tourette syndrome.
A patient should be notified of the possibility of developing an ICD before initiating any dopaminergic treatment for PD, particularly dopamine agonists.
A 150-year-old drug, apomorphine, may reduce off time in patients with Parkinson's disease.
Previous animal model studies have shown PEA to be beneficial in neuroinflammation and provide neuroprotection.
Transcranial Doppler during head-up tilting may be useful for evaluating dizziness.
People with HBV were 76% more likely and those with HCV were 51% more likely to develop PD than people in the comparison group.
Valbenazine is the first drug approved for the treatment of tardive dyskinesia, an adverse effect associated with the use of some antipsychotic medications.
A significant association was found between the apnea-hypopnea index and Epworth Sleepiness Scale scores.
Researchers have developed an assay that accurately identifies small quantities of α-synuclein in cerebrospinal fluid.
There were slower declines in health-related quality of life and mobility when exercise was increased by 30 minutes/week.
The US FDA has approved safinamide as adjunctive therapy in Parkinson's disease to increase "on" time
A 10-month-old girl admitted to PICU with sudden onset of movement disorder was found to have ingested a foreign body.
While their are other factors more strongly associated with risk of cerebral palsy, maternal obesity is modifiable and therefore should be studied further.
Improvements in excessive daytime sleepiness and daytime alertness were observed in the bright light therapy group.
Neurofilament light chain, a blood biomarker, demonstrated high accuracy for distinguishing atypical parkinsonian disorders from Parkinson's disease.
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