Neurobehavioral Disorders

Knowledge Gaps Found for Non-Drug Therapy in Peds ADHD

Knowledge Gaps Found for Non-Drug Therapy in Peds ADHD

There are considerable gaps in knowledge relating to the effectiveness of non-pharmacologic treatments for ADHD in pediatric patients.

Increase in Pediatric ADHD Meds Exposures from 2000 to 2011

Increase in Pediatric ADHD Meds Exposures from 2000 to 2011

From 2000 through 2011 there was an increase in pediatric ADHD medication exposures reported to US poison control centers.

Handgrip Strength Predicts Cognitive Function in Bipolar Disorder, Major Depression

Handgrip Strength Predicts Cognitive Function in Bipolar Disorder, Major Depression

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Handgrip strength was significantly associated with improved visual memory reaction time, prospective memory, and reasoning in patients with bipolar disorder.

Trintellix Labeling Updated With Data on Improved Processing Speed in MDD

Trintellix Labeling Updated With Data on Improved Processing Speed in MDD

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Lundbeck announced that the FDA has approved a sNDA for Trintellix to include data regarding improved processing speed.

IV Methylprednisolone Reduces Duration of Kleine-Levin Syndrome Episodes

IV Methylprednisolone Reduces Duration of Kleine-Levin Syndrome Episodes

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A team of investigators assessed the effect of intravenous administration of methylprednisolone on duration of episodes in adolescent and young adult patients with Kleine-Levin syndrome.

Micronutrient Levels May Be Altered in ADHD

Micronutrient Levels May Be Altered in ADHD

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Levels of magnesium, folate, vitamin B12, zinc, and vitamin D 25-OH were significantly altered in children with ADHD.

The Consequences of Compensation in Autism

The Consequences of Compensation in Autism

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Although compensating for their difficulties may help people with ASD connect with others, get jobs, and successfully navigate social situations, accumulating research suggests it can also lead to exhaustion, burnout, anxiety, and depression.

ADHD Frequently Co-Occurs With Autism Spectrum Disorder

ADHD Frequently Co-Occurs With Autism Spectrum Disorder

Co-occurrence of ADHD is common in children with autism spectrum disorder.

Anomalous Brain Structure ID'd in Preschoolers With ADHD

Anomalous Brain Structure ID'd in Preschoolers With ADHD

Reductions in bilateral frontal, parietal, and temporal lobe gray matter volumes found in ADHD.

Relapse in Major Depression Linked to Brain Cortical Changes

Relapse in Major Depression Linked to Brain Cortical Changes

For patients with major depressive disorde, relapse is associated with brain cortical changes over two years.

Neural Markers of Depression Resilience ID'd in Female Teens

Neural Markers of Depression Resilience ID'd in Female Teens

Adolescent females at high familial risk of depression who do not go on to develop depression have compensatory functional connectivity patterns in emotion regulatory networks.

Risk of Secondary ADHD Higher After Childhood TBI

Risk of Secondary ADHD Higher After Childhood TBI

Severe pediatric traumatic brain injury increases secondary ADHD risk.

PTSD Symptoms May Benefit From Closed-Loop Neurotechnology

PTSD Symptoms May Benefit From Closed-Loop Neurotechnology

Use of HIRREM, a closed-loop, allostatic, acoustic, stimulation neurotechnology can reduce PTSD symptoms, insomnia and depression in veterans.

Transcranial Direct Current Stimulation Effective Add-On for Bipolar Depression

Transcranial Direct Current Stimulation Effective Add-On for Bipolar Depression

For adults with bipolar depression, tDCS seems to be safe and effective as an add-on intervention.

Understanding Poststroke Depression: Risk Factors and Treatment

Understanding Poststroke Depression: Risk Factors and Treatment

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Depression is one of the most commonly reported complications resulting from stroke.

Paternal Selective Serotonin Reuptake Inhibitor Use Linked to ADHD in Offspring

Paternal Selective Serotonin Reuptake Inhibitor Use Linked to ADHD in Offspring

Paternal use of SSRIs before conception is linked to an increased risk of ADHD in offspring.

Alterations in Cerebral Morphometrics Can Help Identify ADHD

Alterations in Cerebral Morphometrics Can Help Identify ADHD

No overall difference in terms of total brain volume or total gray and white matter volume for children with ADHD and control subjects was observed.

Suboptimal Neuromotor Development May Increase Genetic Risk for Schizophrenia

Suboptimal Neuromotor Development May Increase Genetic Risk for Schizophrenia

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Nonoptimal infant neuromotor development was linked to genetic risk for schizophrenia, but not bipolar disorder.

Brexanolone Shows Promise for Postpartum Depression

Brexanolone Shows Promise for Postpartum Depression

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Brexanolone was well tolerated among study participants.

Psychostimulants in Pregnancy Associated With Increased Risk of Preeclampsia, Preterm Birth

Psychostimulants in Pregnancy Associated With Increased Risk of Preeclampsia, Preterm Birth

There is an increased relative risk of preclampsia linked with psychostimulant use while pregnant.

Frequency of Migraine Associated With Depression, Anxiety

Frequency of Migraine Associated With Depression, Anxiety

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Frequency of migraine with or without aura may be correlated with symptoms of anxiety and depression.

Noninvasive Brain Stimulation System Approved for Depression

Noninvasive Brain Stimulation System Approved for Depression

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The FDA has cleared Nexstim's NBT system for the treatment of major depressive disorder.

Prenatal Use of ADHD Medication Linked to Neonatal Morbidity

Prenatal Use of ADHD Medication Linked to Neonatal Morbidity

There is an increased risk of neonatal morbidity associated with exposure to ADHD medication in utero.

Interleukin-6 Blockade, Low C-reactive Protein Levels May Increase Schizophrenia Risk

Interleukin-6 Blockade, Low C-reactive Protein Levels May Increase Schizophrenia Risk

Specific inflammatory biomarkers may have an impact on the risk of developing schizophrenia.

Near-Infrared Light Therapy Effective for Comorbid Depression, TBI

Near-Infrared Light Therapy Effective for Comorbid Depression, TBI

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For patients with comorbid depression and TBI, NILT is effective in bringing remission.

Increased Mortality in Parkinson's Disease Linked to Low Antidepressant Adherence

Increased Mortality in Parkinson's Disease Linked to Low Antidepressant Adherence

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Given the prevalence of depression in Parkinson's disease and the effectiveness of antidepressants, health care providers should promote adherence in clinical practice.

Patients With Intellectual Disability More Susceptible to Movement Side Effects of Antipsychotics

Patients With Intellectual Disability More Susceptible to Movement Side Effects of Antipsychotics

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Incidence of neuroleptic malignant syndrome, akathisia, and parkinsonism was higher in the ID group.

Guidelines Update: Pediatric Acute Onset Neuropsychiatric Syndrome

Guidelines Update: Pediatric Acute Onset Neuropsychiatric Syndrome

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A panel of clinicians from different pediatric fields have developed new guidelines for the treatment of PANS.

Youth Bipolar Disorder Does Not Impact Cognitive Function in Adulthood

Youth Bipolar Disorder Does Not Impact Cognitive Function in Adulthood

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Youth who have bipolar disorder are not affected by a decline in cognitive function into adulthood.

Association of Migraine and PTSD In Pregnant Women

Association of Migraine and PTSD In Pregnant Women

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The findings suggest the importance of screening for posttraumatic stress disorder in this population.

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