Neurodegenerative Diseases

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Beyond Solanezumab: Q&A With Ronald Petersen, MD, PhD

Beyond Solanezumab: Q&A With Ronald Petersen, MD, PhD

Ronald Petersen, MD, PhD, discusses the implications of Eli Lilly's failed solanezumab trial on the future of Alzheimer's disease research.

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Heart Failure, AFib May Precede Mild Alzheimer's Disease

Heart Failure, AFib May Precede Mild Alzheimer's Disease

Early intervention in patients with heart failure or atrial fibrillation may help delay or prevent the onset of mild dementia.

Albuminuria Linked to Cognitive Impairment, Dementia

Albuminuria Linked to Cognitive Impairment, Dementia

In a review, researchers found that elevated levels of albuminuria were linked to worse global cognitive performance and accelerated cognitive decline.

Dementia Combination Tx May Help Reduce Behavioral Symptoms in Alzheimer's

Dementia Combination Tx May Help Reduce Behavioral Symptoms in Alzheimer's

The combination treatment may have benefits, especially for patients who are unresponsive to donezepil alone.

Exposure to Traffic-Related Pollution May Increase Dementia Risk

Exposure to Traffic-Related Pollution May Increase Dementia Risk

The investigators believe the association is related to exposure to pollutants from cars and roads.

Dementia Drug May Elevate Risk for Pneumonia

Dementia Drug May Elevate Risk for Pneumonia

Memantine therapy may put users at greater risk of developing pneumonia.

Alzheimer's Pathologies in Synucleinopathies Indicates Dementia Course

Alzheimer's Pathologies in Synucleinopathies Indicates Dementia Course

Increasing severity of AD pathology inversely correlated to decreases in time from motor symptoms to dementia onset and death.

Estradiol Hormone Therapy May Reduce Mortality in Vascular Dementia

Estradiol Hormone Therapy May Reduce Mortality in Vascular Dementia

Hormone therapy may reduce risk for death from vascular dementia in older women.

Beta-Blockers May Impact Quality of Life in Dementia Patients

Beta-Blockers May Impact Quality of Life in Dementia Patients

Patients experienced a 34% risk of a reduction in the ability to perform daily tasks independently.

Alzheimer's-Related Amyloid Found in the Heart

Alzheimer's-Related Amyloid Found in the Heart

Amyloid beta protein accumulation was present in the hearts of patients with Alzheimer's disease.

Treatment Guidance for Sleep Disorders in Dementia Lacking

Treatment Guidance for Sleep Disorders in Dementia Lacking

There is a clear lack of evidence in the pharmacologic guidance of sleep problems in dementia.

Amyloid Deposits in Alzheimer's Also Affect Heart Health

Amyloid Deposits in Alzheimer's Also Affect Heart Health

Patients with Alzheimer's disease tended to have increased thickness in the wall of their left ventricle.

New Data: Causal Link Between Vitamin D, Alzheimer's Risk

New Data: Causal Link Between Vitamin D, Alzheimer's Risk

The present findings, in combination with those from prior observational research, provide a solid rationale for further randomized trials.

No Benefit for Occupational Therapy in Alzheimer's Disease

No Benefit for Occupational Therapy in Alzheimer's Disease

There seems to be no effect on everyday functioning.

Solanezumab Fails Primary End Point in Alzheimer's Trial

Solanezumab Fails Primary End Point in Alzheimer's Trial

Eli Lilly's investigational Alzheimer's drug failed to meet the primary end point in the phase 3 EXPEDITION3 trial.

Rates of Dementia Decreasing In the United States

Rates of Dementia Decreasing In the United States

Higher levels of education and better management of cardiovascular risk factors may have contributed to this improvement.

VIDEO: Implanted Brain-Computer Interface Allows ALS Patient to Communicate

VIDEO: Implanted Brain-Computer Interface Allows ALS Patient to Communicate

Signals sent to the hand emerge as a typed message on a tablet computer, according to the report.

Preserved Hippocampal Volume in MCI Predicts Progression to Lewy Body Dementia

Preserved Hippocampal Volume in MCI Predicts Progression to Lewy Body Dementia

Patients with mild cognitive impairment with preserved hippocampal volume are at increased risk for dementia with Lewy bodies vs Alzheimer disease.

A Good Diet Translates into Better Functionality in ALS

A Good Diet Translates into Better Functionality in ALS

The foods most negatively correlated with ALSFRS-R score were milk, lunchmeats, and beef and pork.

Can Loneliness Predict Early Alzheimer's Disease?

Can Loneliness Predict Early Alzheimer's Disease?

Future studies should investigate other neuropsychiatric factors for their impact on early signs of AD.

Periodontitis Linked to Increased Dementia Risk

Periodontitis Linked to Increased Dementia Risk

Women aged 75 and older with a history of hypertension, stroke, and periodontitis were at a significantly greater risk of dementia.

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