Neurodegenerative Diseases

Can Proton Pump Inhibitors Raise Dementia Risk?

Can Proton Pump Inhibitors Raise Dementia Risk?

Those who used PPIs were also more likely to use anticholinergic medicines that have been linked to cognitive difficulties

More Evidence Links Mediterranean Diet to Cognition

More Evidence Links Mediterranean Diet to Cognition

Improved cognitive function in older adults is being linked to the Mediterranean diet.

Sleep Quality May Impact Alzheimer's Risk

Sleep Quality May Impact Alzheimer's Risk

Sleep quality is associated with risk of Alzheimer's disease (AD), according to research published in Neurology.

Are Mood Disorders Indicative of Premature Aging?

Are Mood Disorders Indicative of Premature Aging?

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Putative pathogensis insights have grown tremendously in the past 10 years.

Degree of Amyloid Deposition Helps Predict Cognitive Decline

Degree of Amyloid Deposition Helps Predict Cognitive Decline

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The main differentiating factor was the presence of the APOE ε4 allele.

Growing Old Without Alzheimer's Pathology: What's the Secret?

Growing Old Without Alzheimer's Pathology: What's the Secret?

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The main differentiating factor was the presence of the APOE ε4 allele.

Traumatic Brain Injury May Increase Later Risk of Dementia

Traumatic Brain Injury May Increase Later Risk of Dementia

Above-average dementia risk was observed among all participants with traumatic brain injury.

Pain Linked to Memory Decline, Dementia Risk

Pain Linked to Memory Decline, Dementia Risk

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Older adults with chronic pain have been found to have poorer memory and executive function than their younger counterparts.

Medication May Influence Posttraumatic Stress Disorder, Dementia Link

Medication May Influence Posttraumatic Stress Disorder, Dementia Link

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Treatment with psychotropic medications may influence dementia risk in veterans with posttraumatic stress disorder.

Risk for Death Significantly Increased in Patients With Synucleinopathies

Risk for Death Significantly Increased in Patients With Synucleinopathies

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Patients with multiple system atrophy with parkinsonism face the greatest risk for death among synucleinopathies.

Intensive Lifestyle Intervention Holds No Benefit for Cognitive Impairment: Analysis

Intensive Lifestyle Intervention Holds No Benefit for Cognitive Impairment: Analysis

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An intensive lifestyle intervention including diet and exercise resulted in no improvements in cognitive impairment.

Discontinuation of Alzheimer's Treatment Linked to Adverse Events

Discontinuation of Alzheimer's Treatment Linked to Adverse Events

Adverse events were related to over 73% of medication discontinuations.

Dual Gait Task Testing May Predict Progression to Dementia

Dual Gait Task Testing May Predict Progression to Dementia

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Although the study could not confirm that it is a definitive biomarker, the test was highly predictive of outcomes in a cohort of 112 patients with MCI.

Strategy for Reducing Medication Load in Dementia Patients

Strategy for Reducing Medication Load in Dementia Patients

The program, called OASIS, provides employees with the knowledge, skills, and attitudes to meet the needs of residents with dementia using drug-free methods.

Serum Cytokine Levels May Correlate With Cognitive Dysfunction in Alzheimer's Disease

Serum Cytokine Levels May Correlate With Cognitive Dysfunction in Alzheimer's Disease

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Patients with Alzheimer's disease may have higher serum IL-6 levels than subjects with mild cognitive impairment and healthy controls.

Blood Sugar Spikes Linked to Dementia

Blood Sugar Spikes Linked to Dementia

Glucose peaks were tied to greater cognitive decline for those with diabetes and HbA1c 7.0%.

Stroke Prevention May Help Reduce Dementia Risk

Stroke Prevention May Help Reduce Dementia Risk

Delays in anticoagulation treatment resulted in increased risk for dementia.

Alzheimer's Mortality Increasing, But So Is At-Home Care

Alzheimer's Mortality Increasing, But So Is At-Home Care

More patients are dying at home as opposed to in nursing home facilities, suggesting increased support for caregivers is necessary.

Dementia Caregivers Are Often Women

Dementia Caregivers Are Often Women

Family members, especially women, provide most of the care for dementia patients.

New Amyotrophic Lateral Sclerosis Tx Approved by FDA

New Amyotrophic Lateral Sclerosis Tx Approved by FDA

Radicava is the first approved treatment for ALS in over 20 years.

Neuropsychiatric Symptoms May Be a Marker of Preclinical Alzheimer's

Neuropsychiatric Symptoms May Be a Marker of Preclinical Alzheimer's

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Sleep behavior and irritability may be early noncognitive symptoms of Alzheimer's dementia.

Undetected Seizures May Play a Role in Alzheimer's Pathology

Undetected Seizures May Play a Role in Alzheimer's Pathology

Epileptic phenomena are an important component of the dysfunction of the neuronal networks affected by Alzheimer's disease.

Alzheimer's Related Amyloid Deposits Linked to Vascular Risk Factors

Alzheimer's Related Amyloid Deposits Linked to Vascular Risk Factors

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A history of 2 or more vascular risk factors assessed at baseline in the ARIC study was associated with a significantly higher rate of amyloid deposits on PET scans at last visit.

New Gene Linked to Accelerated Decline in Alzheimer's

New Gene Linked to Accelerated Decline in Alzheimer's

Participants with the Met allele lost memory and cognitive skills more rapidly than those without the gene mutation.

Stroke Prevention Strategies May Help Prevent Dementia

Stroke Prevention Strategies May Help Prevent Dementia

Findings from a new study suggest that engaging in stroke prevention strategies may help reduce the risk of dementia.

ALS Prognosis Better Predicted With Addition of MRI Measures

ALS Prognosis Better Predicted With Addition of MRI Measures

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More accurate prediction of ALS prognosis can allow for better planned palliative care.

Alzheimer's Not Linked to a History of Psychiatric Disorders

Alzheimer's Not Linked to a History of Psychiatric Disorders

Patients previously diagnosed with depression or anxiety did not have a greater risk of Alzheimer's.

Overactive Bladder Drugs Tied to Increased Dementia Risk in Diabetes

Overactive Bladder Drugs Tied to Increased Dementia Risk in Diabetes

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Clinicians must keep this potentially increased risk in mind when prescribing long-term use of a specific anticholinergic drug to patients with DM suffering from OAB.

Intracranial Atherosclerotic Plaques May Signify Mild Cognitive Impairment, Dementia

Intracranial Atherosclerotic Plaques May Signify Mild Cognitive Impairment, Dementia

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The association between intracranial atherosclerotic disease and dementia should be the focus of future studies.

Benzodiazepine Use In Alzheimer's: Weighing the Risks and Benefits

Benzodiazepine Use In Alzheimer's: Weighing the Risks and Benefits

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Benzodiazepines increase risk for pneumonia-associated hospitalization, mortality in patients with Alzheimer disease.

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