Neurodegenerative Diseases

Some Women Face Extended High-Risk Period of Developing Alzheimer's

Some Women Face Extended High-Risk Period of Developing Alzheimer's

Some female carriers of the APOE4 gene have a 10-year window where they are more likely to develop Alzheimer's than men.

Dementia Linked to Lithium in Drinking Water

Dementia Linked to Lithium in Drinking Water

The researchers observed a significant difference in lithium exposure for patients with a diagnosis of dementia vs controls.

Dementia Risk Increased in Elderly With Less REM Sleep

Dementia Risk Increased in Elderly With Less REM Sleep

Seniors may be more likely to develop dementia as they age if they spend less time in REM sleep.

Visual Impairment Linked to Cognitive Dysfunction in Seniors

Visual Impairment Linked to Cognitive Dysfunction in Seniors

Visual dysfunction is associated with poor cognitive function in older adults.

Majority of Dementia Care Costs Fall on Families

Majority of Dementia Care Costs Fall on Families

Lifetime care costs are increased for people with dementia.

Cerebral Small Vessel Disease Linked to HTRA1 Mutation

Cerebral Small Vessel Disease Linked to HTRA1 Mutation

Heterozygous mutations may play a role in familial cerebral small vessel disease.

Early Markers of Alzheimer's Disease Identified

Early Markers of Alzheimer's Disease Identified

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Depressive symptoms could be used as an early detection marker of Alzheimer's disease.

Blood Pressure Variability Associated With Elderly Dementia Risk

Blood Pressure Variability Associated With Elderly Dementia Risk

There is a higher risk of all-cause dementia, vascular dementia, and Alzheimer's disease in the elderly with increased BP variability.

Cognitive Decline Related to Site Specific Mid-Life Adiposity

Cognitive Decline Related to Site Specific Mid-Life Adiposity

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An increase in weight ≥5% was associated with lower cognitive scores.

Hearing Loss in Elderly Linked to Greater Dementia Risk

Hearing Loss in Elderly Linked to Greater Dementia Risk

Participants with self-reported or objective moderate to poor hearing were more likely to have a dementia diagnosis.

Dementia Risk Significantly Increased for Individuals Born in High Stroke Mortality States

Dementia Risk Significantly Increased for Individuals Born in High Stroke Mortality States

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Birthplace is a significant risk factor for dementia, even after adjusting for educational levels, race, and life-course vascular risk factors.

Differentiating Dementia Subtypes With Transcranial Magnetic Stimulation

Differentiating Dementia Subtypes With Transcranial Magnetic Stimulation

Using a transcranial magnetic stimulation approach might make it easier to distinguish Alzheimer's disease from frontotemporal dementia.

Functional Improvements in Alzheimer's Possible With Medication, Training

Functional Improvements in Alzheimer's Possible With Medication, Training

Alzheimer's patients can relearn some basic skills such as dressing and bathing themselves.

Sleep-Disordered Breathing, OSA Associated With Amyloid Deposition

Sleep-Disordered Breathing, OSA Associated With Amyloid Deposition

There may be a relationship between sleep disordered breathing and Alzheimer's disease caused by biological changes in the brain.

Socializing One Hour Per Week Improves QOL in Dementia

Socializing One Hour Per Week Improves QOL in Dementia

Small increases in social interaction benefits older adults with dementia.

HbA1c, Plasma Glucose Linked to Alzheimer's in Diabetes

HbA1c, Plasma Glucose Linked to Alzheimer's in Diabetes

For T2DM patients, FPG and HbA1c are independently associated with Alzheimer's disease.

Can Proton Pump Inhibitors Raise Dementia Risk?

Can Proton Pump Inhibitors Raise Dementia Risk?

Those who used PPIs were also more likely to use anticholinergic medicines that have been linked to cognitive difficulties

More Evidence Links Mediterranean Diet to Cognition

More Evidence Links Mediterranean Diet to Cognition

Improved cognitive function in older adults is being linked to the Mediterranean diet.

Sleep Quality May Impact Alzheimer's Risk

Sleep Quality May Impact Alzheimer's Risk

Sleep quality is associated with risk of Alzheimer's disease (AD), according to research published in Neurology.

Are Mood Disorders Indicative of Premature Aging?

Are Mood Disorders Indicative of Premature Aging?

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Putative pathogensis insights have grown tremendously in the past 10 years.

Degree of Amyloid Deposition Helps Predict Cognitive Decline

Degree of Amyloid Deposition Helps Predict Cognitive Decline

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The main differentiating factor was the presence of the APOE ε4 allele.

Growing Old Without Alzheimer's Pathology: What's the Secret?

Growing Old Without Alzheimer's Pathology: What's the Secret?

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The main differentiating factor was the presence of the APOE ε4 allele.

Traumatic Brain Injury May Increase Later Risk of Dementia

Traumatic Brain Injury May Increase Later Risk of Dementia

Above-average dementia risk was observed among all participants with traumatic brain injury.

Pain Linked to Memory Decline, Dementia Risk

Pain Linked to Memory Decline, Dementia Risk

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Older adults with chronic pain have been found to have poorer memory and executive function than their younger counterparts.

Medication May Influence Posttraumatic Stress Disorder, Dementia Link

Medication May Influence Posttraumatic Stress Disorder, Dementia Link

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Treatment with psychotropic medications may influence dementia risk in veterans with posttraumatic stress disorder.

Risk for Death Significantly Increased in Patients With Synucleinopathies

Risk for Death Significantly Increased in Patients With Synucleinopathies

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Patients with multiple system atrophy with parkinsonism face the greatest risk for death among synucleinopathies.

Intensive Lifestyle Intervention Holds No Benefit for Cognitive Impairment: Analysis

Intensive Lifestyle Intervention Holds No Benefit for Cognitive Impairment: Analysis

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An intensive lifestyle intervention including diet and exercise resulted in no improvements in cognitive impairment.

Discontinuation of Alzheimer's Treatment Linked to Adverse Events

Discontinuation of Alzheimer's Treatment Linked to Adverse Events

Adverse events were related to over 73% of medication discontinuations.

Dual Gait Task Testing May Predict Progression to Dementia

Dual Gait Task Testing May Predict Progression to Dementia

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Although the study could not confirm that it is a definitive biomarker, the test was highly predictive of outcomes in a cohort of 112 patients with MCI.

Strategy for Reducing Medication Load in Dementia Patients

Strategy for Reducing Medication Load in Dementia Patients

The program, called OASIS, provides employees with the knowledge, skills, and attitudes to meet the needs of residents with dementia using drug-free methods.

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