Neurodevelopmental Disorders

Blood Pressure Screen in Down Syndrome May Help Identify Moyamoya Syndrome Risk

Blood Pressure Screen in Down Syndrome May Help Identify Moyamoya Syndrome Risk

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Higher blood pressure was predicted by higher posterior circulation involvement and bilateral disease.

Biomarkers of Alzheimer Disease Observed in Down Syndrome

Biomarkers of Alzheimer Disease Observed in Down Syndrome

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Neurological and neuropsychological examinations were performed to assess intellectual disabilities, and biological assays were performed on collected CSF and plasma.

Neurodevelopmental Anomalies, Birth Defects Linked to Zika ID'd

Neurodevelopmental Anomalies, Birth Defects Linked to Zika ID'd

Many children of mothers with evidence of confirmed or possible Zika virus infection during pregnancy do not undergo all recommended evaluations.

Specific Neuroimaging Findings May Predict School-Age Cognitive Disability in Preterm Infants

Specific Neuroimaging Findings May Predict School-Age Cognitive Disability in Preterm Infants

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Severe and adverse late findings on neonatal cranial ultrasound and MRI in preterm infants, including cerebellar lesions and white matter abnormalities, may predict cognitive impairment and disability at 6 to 7 years of age.

Hypertensive Disorders of Pregnancy May Be Associated With Increased Autism and ADHD Risk

Hypertensive Disorders of Pregnancy May Be Associated With Increased Autism and ADHD Risk

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A literature review was conducted to assess the association between hypertensive disorders of pregnancy and neurodevelopmental disorders in offspring.

Increased Multigenerational ADHD Risk Linked to DES Exposure During Pregnancy

Increased Multigenerational ADHD Risk Linked to DES Exposure During Pregnancy

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Investigators sought to investigate the association between the use of diethylstilbestrol during pregnancy on risk for ADHD in subsequent generations.

NEURO Study: Neonatal neuroimaging with strong negative predictive value for developmental outcomes

In multivariate analyses, adverse late cranial ultrasound findings were an independent risk factor for full scale IQ scores.

Neurodevelopment in Preemies Not Affected by Glucocorticoid Therapy

Neurodevelopment in Preemies Not Affected by Glucocorticoid Therapy

There is no increased rate of neurodevelopmental disability in preterm infants using inhaled glucocorticoids.

Despite Improved Survival, Developmental Delay Still Common in Preemies

Despite Improved Survival, Developmental Delay Still Common in Preemies

Survival without neuromotor disabilities in preterm infants has increased.

KCNB1 Mutations Associated With Variable Neurodevelopmental Disorder Phenotypes

KCNB1 Mutations Associated With Variable Neurodevelopmental Disorder Phenotypes

De novo KCNB1 missense and loss-of-function variants are associated with neurodevelopmental disorders.

Deletion, Duplication at 16p11.2 Linked to Neuroanatomic Anomalies

Deletion, Duplication at 16p11.2 Linked to Neuroanatomic Anomalies

Carriers of a deletion or duplication at 16p11.2 have neuroanatomic abnormalities that are associated with cognitive and behavioral impairment.

Neurodevelopment Not Adversely Affected by Hydrocortisone Tx in Preemies

Neurodevelopment Not Adversely Affected by Hydrocortisone Tx in Preemies

No statistically significant differences between the groups in the distribution of patients without neurodevelopmental impairment were observed.

FDA: Beware of Purported Autism Cures, Treatments

FDA: Beware of Purported Autism Cures, Treatments

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The FDA has warned and/or taken action against a number of companies that have made improper claims about the intended use of their products to treat or cure autism.

Autism Spectrum Disorder Linked to Sex-Based Cortical Thickness

Autism Spectrum Disorder Linked to Sex-Based Cortical Thickness

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Female participants with phenotypic male neuroanatomical features had an increased risk for autism spectrum disorder.

Risk of Zika Virus-Related Birth Defects in Pregnant Women

Risk of Zika Virus-Related Birth Defects in Pregnant Women

The CDC report only accounts for physical birth defects, as researchers note that the full scope of developmental defects has yet to be recorded.

ADHD Associated with Delays in Subcortical Brain Volume Maturation

ADHD Associated with Delays in Subcortical Brain Volume Maturation

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Significant differences in volume were apparent in the amygdala, caudate, hippocampus, and putamen.

Antiretroviral Therapy May Improve Neurodevelopmental Outcomes in HIV-Infected Infants

Antiretroviral Therapy May Improve Neurodevelopmental Outcomes in HIV-Infected Infants

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Early detection and robust treatment are critical to limiting deficits in achieving developmental milestones in HIV-infected infants.

Early Autism Diagnosis Continues to Face Roadblocks

Early Autism Diagnosis Continues to Face Roadblocks

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Despite increased awareness, barriers to earlier diagnosis of autism spectrum disorder still persist.

No Difference in Neurodevelopment in Children Conceived by Assisted Reproduction

No Difference in Neurodevelopment in Children Conceived by Assisted Reproduction

Researchers found no difference in neurodevelopment in children conceived by ART.

Parental Obesity Linked to Delays in Child Development

Parental Obesity Linked to Delays in Child Development

In both parents, a BMI ≥35 kg/m² suggested a likelihood that the child would fail the problem-solving domain.

Quantifying Genetic Risk in Attention-Deficit/Hyperactivity Disorder

Quantifying Genetic Risk in Attention-Deficit/Hyperactivity Disorder

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PRS presents a good tool to measure genetic loading of ADHD variants, suggesting which cases are most likely to persist.

Blood Test May Identify Risk of Fetal Alcohol Spectrum Disorders

Blood Test May Identify Risk of Fetal Alcohol Spectrum Disorders

Moderate to high levels of drinking during early pregnancy were associated with significant alterations in circulating microRNAs in maternal blood.

No Neurodevelopmental Benefit for Donor Breast Milk vs Formula in Low-Weight Infants

No Neurodevelopmental Benefit for Donor Breast Milk vs Formula in Low-Weight Infants

Neurodevelopment improvement should not be considered a treatment goal of supplementing donor milk, the authors concluded.

Antidepressant Bupropion Crosses Placental Barrier

Antidepressant Bupropion Crosses Placental Barrier

Effects of fetal exposure are yet to be determined.

Autism Linked to Exposure to PCB Chemicals During Pregnancy

Autism Linked to Exposure to PCB Chemicals During Pregnancy

Although PCB chemicals were banned int he 1970s, they still linger in the environment.

Guidelines Update: Diagnosing Fetal Alcohol Spectrum Disorder

Guidelines Update: Diagnosing Fetal Alcohol Spectrum Disorder

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The new guidelines include a step-by-step diagnostic algorithm for use in the clinical setting, as well as a special emphasis on neurobehavioral impairment.

Clinician, Parent Interaction in Neonatal Encephalopathy

Clinician, Parent Interaction in Neonatal Encephalopathy

Clear communication is key during this high-stress time.

Hearing Impairment May Help Identify Autism Risk, Severity

Hearing Impairment May Help Identify Autism Risk, Severity

Children with autism had a hearing deficit within a specific frequency.

No Link Between Labor Induction and Autism, New Study Says

No Link Between Labor Induction and Autism, New Study Says

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The results are contrary to results from a prior large population study.

Despite Health Insurance Mandates, Autism Still Underdiagnosed

Despite Health Insurance Mandates, Autism Still Underdiagnosed

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The authors suggest that it's "perhaps not a fair direct comparison" to note that the CDC&P estimate of community prevalence for ASD is 15 per 1000 children.

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