Neuromuscular Disorders

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Comorbidities in Multiple Sclerosis: Effects on DMTs, the Treatment Team, and More

Comorbidities in Multiple Sclerosis: Effects on DMTs, the Treatment Team, and More

Having a higher burden of comorbidities is associated with greater disability progression and lower QoL, as well as increased healthcare utilization and mortality.

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Nusinersen May Be Effective for Short-Term Motor Function Improvements in Spinal Muscular Atrophy

Nusinersen May Be Effective for Short-Term Motor Function Improvements in Spinal Muscular Atrophy

Nusinersen, an antisense oligonucleotide that increases functional SMN protein production from SMN2, was clinically effective for improving motor function.

Comorbidities in Multiple Sclerosis: Effects on DMTs, the Treatment Team, and More

Comorbidities in Multiple Sclerosis: Effects on DMTs, the Treatment Team, and More

Having a higher burden of comorbidities is associated with greater disability progression and lower QoL, as well as increased healthcare utilization and mortality.

Rates of Multiple Sclerosis Relapses Vary Before, During, and After Pregnancy

Rates of Multiple Sclerosis Relapses Vary Before, During, and After Pregnancy

Investigators sought to determine relapse rates of multiple sclerosis decrease prior to pregnancy, during pregnancy, and postpartum.

Tiglutik Now Available for the Treatment of Amyotrophic Lateral Sclerosis

Tiglutik Now Available for the Treatment of Amyotrophic Lateral Sclerosis

Tiglutik is supplied as a thickened riluzole liquid that is intended to ease administration for patients with dysphagia.

A New Look at Demyelination and White Matter Density in Multiple Sclerosis

A New Look at Demyelination and White Matter Density in Multiple Sclerosis

Investigators propose that myelocortical multiple sclerosis may be a subtype of multiple sclerosis.

Cannabinoids Mildly Effective for Treating MS Symptoms in Adults

Cannabinoids Mildly Effective for Treating MS Symptoms in Adults

Cannabinoids may be mildly effective at treating spasticity, pain, and bladder dysfunction in adults with multiple sclerosis.

Fingolimod shows superior efficacy to interferon beta-1a in pediatric multiple sclerosis: the PARADIGMS trial

Among pediatric patients with relapsing multiple sclerosis, fingolimod was associated with a lower annualized rate of relapse and lower incidence of new lesions identified on T2-weighted magnetic resonance imaging (MRI) compared to interferon beta-1a.

Physical Activity Decreases Vascular Comorbidities in Multiple Sclerosis

Physical Activity Decreases Vascular Comorbidities in Multiple Sclerosis

Investigators examine the role of physical activity and exercise in the modification of vascular comorbidities and risk factors in individuals with multiple sclerosis.

DMTs Do Not Moderate Disability in Patients With MS and Diabetes, Other Comorbidities

DMTs Do Not Moderate Disability in Patients With MS and Diabetes, Other Comorbidities

All participants were smokers or had either diabetes, cancer, depression, cardiovascular, respiratory, thyroid, or gastrointestinal disease and were receiving a DMT.

Glatiramer Acetate Associated With Long-Term Disability Improvements in MS

Glatiramer Acetate Associated With Long-Term Disability Improvements in MS

Natural history data from a subset of patients from the British Columbia MS database between 1980 to 1996 were used to create a continuous Markov model to model the projected course of disease in untreated people with RMS.

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