Pain News Archive

FDA Approves Device for Tx of Chronic Pain

FDA Approves Device for Tx of Chronic Pain

The Intellis platform has been announced as a way to manage certain types of chronic pain.

Gabapentinoid Prescribing Trends: Are We Using Too Much?

Gabapentinoid Prescribing Trends: Are We Using Too Much?

As a response to the opioid epidemic, clinicians may be overprescribing gabapentinoids.

Excessive Opioid Prescribing Still Rampant in US

Excessive Opioid Prescribing Still Rampant in US

Even though there are concerns about opioid addiction and misuse, there are still more than 1/3 of Americans using them.

Ketamine Update: Usage, Benefits, and Current Research

Ketamine Update: Usage, Benefits, and Current Research

Ketamine was found to alleviate a number of pain-related conditions, and a number of clinical trials investigating its efficacy are ongoing.

Opioid Dose Reduction May Improve Quality of Life in Chronic Pain

Opioid Dose Reduction May Improve Quality of Life in Chronic Pain

Quality of life and improved pain and function may be achieved by reducing opioid doses.

The Role of Hospitalists in Addressing the Opioid Crisis

The Role of Hospitalists in Addressing the Opioid Crisis

Hospitalists must use opioids judiciously, including adhering to specific dose limits and setting expectations for pain control, medication stop dates, and refills.

Acceptance Therapy May Reduce Opioid Dependence in Patients

Acceptance Therapy May Reduce Opioid Dependence in Patients

Patients with chronic pain may have a lower risk of becoming addicted to opioids if they are taught coping skills.

Peripheral Nerve Stimulation Effective for Postherpetic Neuralgia

Peripheral Nerve Stimulation Effective for Postherpetic Neuralgia

PNS can be beneficial for chronic intractable pain secondary to postherpetic neuralgia.

Curbing the Opioid Epidemic: A National Academies of Science Report

Curbing the Opioid Epidemic: A National Academies of Science Report

The NASEM report, which was commissioned by the FDA, gives an update on current research in the pain field.

Pain Linked to Memory Decline, Dementia Risk

Pain Linked to Memory Decline, Dementia Risk

Older adults with chronic pain have been found to have poorer memory and executive function than their younger counterparts.

FDA Moves to Remove Opioid From the Market

FDA Moves to Remove Opioid From the Market

An FDA panel previously voted that the drug's benefits no longer outweigh its risks.

Preclinical Pain in Amyotrophic Lateral Sclerosis May Be a Marker for Diagnosis, Treatment

Preclinical Pain in Amyotrophic Lateral Sclerosis May Be a Marker for Diagnosis, Treatment

Reports of pain may indicate a preclinical course of amyotrophic lateral sclerosis.

New Guidelines: Opioids for Chronic Pain in the VA Health System

New Guidelines: Opioids for Chronic Pain in the VA Health System

The VA and DoD issue a clinical practice guideline regarding opioid therapy for chronic pain in veterans.

Neurofeedback Aids in Reducing Nerve Damage from Chemo

Neurofeedback Aids in Reducing Nerve Damage from Chemo

Clinically and statistically significant reductions in peripheral neuropathy were seen following neurofeedback.

Neural Targeting Spinal Cord Stimulation Superior for Axial Low Back Pain

Neural Targeting Spinal Cord Stimulation Superior for Axial Low Back Pain

Spinal cord stimulation using precision approach via 3D neural targeting shows superior efficacy in treating chronic axial low back pain compared with a trial-and-error method to achieve desired paresthesia.

Updated Guidelines for Treatment of Low Back Pain

Updated Guidelines for Treatment of Low Back Pain

The recommendations promote the use of hot compresses and physical therapy as first-line treatment of low back pain.

VIDEO: Opioid Addiction May Be Linked to Genetic Variant

New research suggests that opioid addiction may be linked to a genetic variant, and more personalized treatment may help those with the change.

Clinical Massage, Guided Imagery May Improve Insomnia, Pain

Clinical Massage, Guided Imagery May Improve Insomnia, Pain

Interventions with clinical massage or guided imagery may help ease pain and anxiety in patients in a progressive care unit.

Opioid Abuse May Be Linked to Sudden-Onset Amnesia

Opioid Abuse May Be Linked to Sudden-Onset Amnesia

The abuse of opioids or other substances may cause short-term amnesia.

Spinal Cord Stimulation May Reduce Opioid Use in Chronic Pain

Spinal Cord Stimulation May Reduce Opioid Use in Chronic Pain

Patients with successful spinal cord stimulation implants had significantly reduced opioid use 1 year post-implant.

Treating Pain in Depression May Help Improve Cognition

Treating Pain in Depression May Help Improve Cognition

Effectively treating pain may help improve cognitive and functional outcomes in patients with depression.

FDA Updates Opioid Drug Label Information

FDA Updates Opioid Drug Label Information

The FDA instituted widespread updates to product labeling for opioid medications in December, 2016.

Veterans Experience More Pain Than General Population

Veterans Experience More Pain Than General Population

Rates of severe pain were significantly higher in veterans with back and jaw pain, severe headaches or migraine, and neck pain.

FDA Issues Warning for Children, Pregnant Women With Extended Exposure to Anesthetics

FDA Issues Warning for Children, Pregnant Women With Extended Exposure to Anesthetics

The US FDA is requiring that label changes be made to reflect the risks involved with extended exposure to anesthetics and sedatives in children and pregnant women.

Is Vitamin D the Answer in Chronic Widespread Pain?

Is Vitamin D the Answer in Chronic Widespread Pain?

After treatment, there were marked decreases in visual analog scale (VAS)-pain, VAS-asthenia, severity of waking unrefreshed, tender point count, and Beck Depression Inventory.

Quality Improvements for Pain Management in the ER

Quality Improvements for Pain Management in the ER

The researchers observed a 47.5% increase in the percentage of participants who had a final pain score of 4 or less out of 10.

Pregabalin vs Gabapentin for Neuropathic Pain: Which Costs Less?

Pregabalin vs Gabapentin for Neuropathic Pain: Which Costs Less?

Even after loss of exclusivity, pregabalin has lower health care costs than gabapentin.

DEA Delays Decision to Ban Kratom

DEA Delays Decision to Ban Kratom

Kratom may be used to develop nonaddictive alternatives to opioids.

Alternative Treatments for the Management of Chronic Pain

Alternative Treatments for the Management of Chronic Pain

Alternative treatments include endomorphins, spinal cord stimulation, and psychotherapy.

Consequences of Limiting Physicians' Prescribing of Buprenorphine

Consequences of Limiting Physicians' Prescribing of Buprenorphine

Novice prescribers cited insufficient access to substance abuse counseling for patients, as well as insufficient access to more experienced prescribers, as reasons for not treating more patients.

Should Pain Treatments Target the Brain or Body?

Should Pain Treatments Target the Brain or Body?

Pain treatments often target either the brain or body, but data show that treatments often benefit both.

Acupuncture for Treatment of Chronic Pain Conditions

Acupuncture for Treatment of Chronic Pain Conditions

A patient with a baseline pain score of 60 on a scale of 0 to 100 would be expected to have a pain score of 45 after a non-acupuncture intervention; 35 after a sham acupuncture intervention; and 30 after true acupuncture.

Alternative Pain Management Therapies Effective

Alternative Pain Management Therapies Effective

Approaches such as acupuncture, massage, and tai chi may ease discomfort.

Sleep Disturbance Common in Chronic Pain

Sleep Disturbance Common in Chronic Pain

Opioid usage may exacerbate the problem.

Elderly May Be at Lower Risk of Opioid Abuse

Elderly May Be at Lower Risk of Opioid Abuse

Patients who underwent thoracic surgery were at the greatest risk of long-term opioid use.

Illicit Use of Gabapentin on the Rise

Illicit Use of Gabapentin on the Rise

A surprising number of patients already prescribed opioids were found to be abusing gabapentin.

Buprenorphine Implant Effective for Reducing Opioid Dependence

Buprenorphine Implant Effective for Reducing Opioid Dependence

The 6-month implant is more expensive than the pills, costing about $4,900 -- or more than $800 a month.

Risk of Chronic Opioid Use After Common Surgeries

Risk of Chronic Opioid Use After Common Surgeries

A restricted number of surgical procedures are not associated with increased incidence of chronic opioid use.

Medical Schools Stepping Up Opioid Abuse Training

Medical Schools Stepping Up Opioid Abuse Training

American medical school students spend much less time learning about pain than their international peers.

Opioid Use Mortality Linked to Cardiovascular Complications

Opioid Use Mortality Linked to Cardiovascular Complications

Much of the risk is related to cardiovascular complications, not overdoses.

FDA Approval: First Probuphine Implant for Opioid Dependence

FDA Approval: First Probuphine Implant for Opioid Dependence

This new form of treatment is designed to last 6 months.

Opioid Prescriptions Drop, but Overdose Deaths Still Rising

Opioid Prescriptions Drop, but Overdose Deaths Still Rising

There has been a 12 to 18% drop in opioid prescriptions since 2012.

Sleep Disruption Alters Pain Sensitivity

Sleep Disruption Alters Pain Sensitivity

Sleep disruption alters positive affective pain modulation.

FDA Considers Mandatory Opioid Prescribing Training

FDA Considers Mandatory Opioid Prescribing Training

An FDA committee will meet this week to review the risk-management plans.

Naltrexone Injection Reduces Opioid Relapse Risk

Naltrexone Injection Reduces Opioid Relapse Risk

The effects of the opioid-relapse prevention treatment waned after treatment discontinuation.

Opioids Being Prescribed for Longer Than Recommended

Opioids Being Prescribed for Longer Than Recommended

Twenty-five percent of doctors write month-long opioid prescriptions.

FDA Issues Guidance on Generic Abuse-Deterrent Opioids

FDA Issues Guidance on Generic Abuse-Deterrent Opioids

The new guideline is the latest in an overhaul designed to curb opioid abuse.

Opioid Medications to Get New Boxed Warnings

Opioid Medications to Get New Boxed Warnings

Revised labeling will occur across all types of opioids.

Physicians Sound Off On New CDC Opioid Guidelines

Physicians Sound Off On New CDC Opioid Guidelines

Some concerns include a lack of evidence underlying recommendations.

Non-Opioid Pathway Could Alter the Way We Treat Chronic Pain

Non-Opioid Pathway Could Alter the Way We Treat Chronic Pain

While mindfulness meditation has previously been associated with pain relief, the mechanistic action behind this has been unclear.

CDC Issues Guideline for Prescribing Opioids for Chronic Pain

CDC Issues Guideline for Prescribing Opioids for Chronic Pain

The new guidelines come in the wake of an opioid overdose epidemic in the U.S.

Informative Letters Fail to Stop Physicians From Overprescribing

Informative Letters Fail to Stop Physicians From Overprescribing

Targeted physicians prescribed 400% more controlled substances than their peers.

FDA Accepts NDA for Controlled Opioid Agonist

FDA Accepts NDA for Controlled Opioid Agonist

The FDA has accepted an NDA for Arymo ER (morphine sulfate; Egalet) extended-release tablets.

Opioids Associated With Infection Risk in Rheumatoid Arthritis

Opioids Associated With Infection Risk in Rheumatoid Arthritis

Those who presented with serious infections were more likely to currently be using opioids.

Functional MRI May Help In Pain Medicine Development

Functional MRI May Help In Pain Medicine Development

Functional MRI with central sensitization was found beneficial for selecting analgesics.

FDA Launches New Plan to Reduce Opioid Overdose

FDA Launches New Plan to Reduce Opioid Overdose

There were 18 893 deaths involving prescription opioids in the US in 2014.

Chronic Opioid Use May Raise Risk of Depression

Chronic Opioid Use May Raise Risk of Depression

Long duration of opioid use associated with new onset depression.

Opioid Exposure Linked to Low Testosterone Levels

Opioid Exposure Linked to Low Testosterone Levels

Odds of low levels increased with age and comorbidities.

Majority Continue to Receive Opioid Prescriptions After Overdose

Majority Continue to Receive Opioid Prescriptions After Overdose

More than 90% of patients with chronic pain continue to receive prescription opioids even after an overdose.

Neuropsychiatric Symptoms Often Manifest in Rheumatoid Arthritis

Neuropsychiatric Symptoms Often Manifest in Rheumatoid Arthritis

The most common symptom was headache, potentially resulting from the disease process, treatment, or comorbid conditions unrelated to RA.

Comorbid Insomnia Contributes to Brain Changes in Fibromyalgia

Comorbid Insomnia Contributes to Brain Changes in Fibromyalgia

Comorbid disease types appear to elevate dysfunction in the brain.

Distribution of Opioid Prescribing is Widespread, Study Finds

Distribution of Opioid Prescribing is Widespread, Study Finds

Despite data to the contrary, the study found that opioid prescribing is widespread.

Sleep-Deprived Anesthesiologists Pose a Danger to Patients

Sleep-Deprived Anesthesiologists Pose a Danger to Patients

Sleep deprivation impacts patient safety and quality of care.

Bridion Wins FDA Approval for Neuromuscular Blockade Reversal

Bridion Wins FDA Approval for Neuromuscular Blockade Reversal

The drug reverses the effects of rocuronium bromide and vecuronium bromide.

FDA Approves Narcan Nasal Spray to Reverse Opioid Overdose

FDA Approves Narcan Nasal Spray to Reverse Opioid Overdose

The drug can reverse the effects of opioid overdose in as little as 2 minutes.

Implants Could Block Pain Signals From the Brain

Implants Could Block Pain Signals From the Brain

Researchers have developed small, fully implantable devices that may one day be used to block pain signals before they reach the brain.

Opioid Receptors in the Brain May Multiply to Cope with Chronic Pain

Opioid Receptors in the Brain May Multiply to Cope with Chronic Pain

The pain thresholds of participants positively correlated with their opioid receptor availability.

Transcranial Direct Current Stimulation May Reduce Fibromyalgia Pain

Transcranial Direct Current Stimulation May Reduce Fibromyalgia Pain

A mean of 15 HD-tDCS sessions was found to reduce fibromyalgia pain by 50%.

Revised Questionnaire May More Accurately Diagnose Fibromyalgia

Revised Questionnaire May More Accurately Diagnose Fibromyalgia

The study looked at differences between fibromyalgia, lupus, and rheumatoid arthritis.

Autoantibodies in Shingles Virus May Drive Postherpetic Neuralgia

Autoantibodies in Shingles Virus May Drive Postherpetic Neuralgia

The findings suggest that anti-cytokine immunodeficiency may contribute to development of PHN.

High-Frequency Spinal Cord Stimulation Curbs Chronic Back, Leg Pain

High-Frequency Spinal Cord Stimulation Curbs Chronic Back, Leg Pain

An SCS system that delivered 10-kHz high-frequency therapy was nearly twice as effective at relieving pain as traditional low-frequency SCS.

Fibromyalgia Patients Likely Prescribed Opioids Despite Guidelines

Fibromyalgia Patients Likely Prescribed Opioids Despite Guidelines

Those taking opioids are less likely to receive guideline-recommended therapy.

Rates of Nonmedical Opioid Use, Treatment Not Improving

Rates of Nonmedical Opioid Use, Treatment Not Improving

The prevalence of prescription opioid use disorder grew from 2003 to 2013.

Poor Mental Health Could Increase Risk of Chronic Pain in Adolescents

Poor Mental Health Could Increase Risk of Chronic Pain in Adolescents

Mental disorders have been found to be predictors for the onset of chronic pain in adolescents.

Cannabis Appears Safe for Treatment of Chronic Pain

Cannabis Appears Safe for Treatment of Chronic Pain

Use of cannabis modestly reduced participants' pain scores.

Guidelines for Treating Opioid Abuse Released

Guidelines for Treating Opioid Abuse Released

The guidelines recommend that first responders be trained to use the opioid blocker naloxone.

Chronic Pain and Tinnitus: What's the Connection?

Chronic Pain and Tinnitus: What's the Connection?

A new report concluded that there is an unexpected link between two conditions that reorganize the brain: tinnitus and chronic pain.

Access to Mental Health Services Important for Chronic Pain Patients

Access to Mental Health Services Important for Chronic Pain Patients

Depression, substance abuse, and suicidal ideation are commonly reported in patients who have chronic pain.

Adolescents with Chronic Pain Require Personalized Care

Adolescents with Chronic Pain Require Personalized Care

How adolescents approach their chronic pain condition has an effect on how they will experience their condition in adulthood.

Antidepressants May Contribute to Neuropathic Pain Treatment

Antidepressants May Contribute to Neuropathic Pain Treatment

Commonly used antidepressants appear to target specific neurotransmitters in the brain that regulate chronic pain symptoms.

Corticosteroid Injections Only Offer Temporary Relief for Back Pain

Corticosteroid Injections Only Offer Temporary Relief for Back Pain

Corticosteroid injections were ineffective for people with spinal stenosis.

Juvenile Fibromyalgia Improves with Physical, Occupational, and Psychotherapy

Juvenile Fibromyalgia Improves with Physical, Occupational, and Psychotherapy

An intensive program of PT, OT, and psychotherapy significantly improved pain without the help of medication.

FDA Approves Oxycontin for Pediatric Patients

FDA Approves Oxycontin for Pediatric Patients

The FDA has approved labeling updates for Oxycontin extended-release tablets for patients aged 11 and older.

Pain Prevalent Among U.S. Adults

Pain Prevalent Among U.S. Adults

The report revealed that approximately 25.3 million adults had pain every day for the preceding 3 months.

High-Frequency Spinal Stimulation Superior for Back, Leg Pain

High-Frequency Spinal Stimulation Superior for Back, Leg Pain

The benefits of high-frequency stimulation were sustained over 12 months.

AAN Joins Opioid Abuse Task Force

AAN Joins Opioid Abuse Task Force

The task force hopes to develop protocols to curb abuse of opioids.

Heavy Drinking for Chronic Pain? Not So Fast

Heavy Drinking for Chronic Pain? Not So Fast

Chronic drinking only causes further deterioration, U.S. physicians warn.

Spinal Cord Stimulation Therapy Relieves Chronic Back, Leg Pain

Spinal Cord Stimulation Therapy Relieves Chronic Back, Leg Pain

In the HF10 therapy group, 85% of back pain and 83% of leg pain patients experienced a 50% reduction in pain or greater.

Inhaling Cannabis May Reduce Pain in Diabetic Peripheral Neuropathy

Inhaling Cannabis May Reduce Pain in Diabetic Peripheral Neuropathy

Researchers observed a dose-dependent reduction in pain in patients with diabetic peripheral neuropathy.

Patients Don't Inform Doctors of Alternative Treatments for Chronic Pain

Patients Don't Inform Doctors of Alternative Treatments for Chronic Pain

Many physicians don't ask about alternative therapies, so patients don't disclose them.

Smokers, Drug Abusers More Likely to Abuse Opioids

Smokers, Drug Abusers More Likely to Abuse Opioids

People with a history of smoking or abusing drugs are at the highest risk of using opioids for the long-term.

Women with Fibromyalgia Less Physically Active, More Sedentary

Women with Fibromyalgia Less Physically Active, More Sedentary

Notably, most healthy controls are also not meeting current recommendations for physical activity and steps.

Physicians Misinformed And Unaware Of Opioid Dangers

Physicians Misinformed And Unaware Of Opioid Dangers

Physicians, as well as patients, are unaware and misinformed of the dangers that come with opioid use

New Capsule Safe And Effective for Opioid-Induced Constipation

New Capsule Safe And Effective for Opioid-Induced Constipation

New oral naxalone sustained release (NSR) capsule allows for successful treatment of opioid-induced constipation.

Fibromyalgia Symptoms Eased With Hyperbaric Oxygen Therapy

Fibromyalgia Symptoms Eased With Hyperbaric Oxygen Therapy

Insurance companies may not cover the cost for hyperbaric oxygen therapy since it is not FDA-approved yet.

Napping Linked to Increased Symptom Severity in Fibromyalgia

Napping Linked to Increased Symptom Severity in Fibromyalgia

Napping is often used as a coping mechanism for people with fibromylagia.

Ultrasound Training Included in Most Chronic Pain Fellowships

Ultrasound Training Included in Most Chronic Pain Fellowships

Use of ultrasound guidance in interventional pain procedures is still lacking.

Sleep May Have a Protective Effect on Pain

Sleep May Have a Protective Effect on Pain

Animal models suggest that naloxone may be a potential microglia inhibitor, which can also impact the sleep-pain relationship.

Microglia Activation Causes Depression, Anxiety in Chronic Pain

Microglia Activation Causes Depression, Anxiety in Chronic Pain

In chronic pain patients, increased activation of microglia can cause depression and anxiety.

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