Pain News Archive
The US FDA is requiring that label changes be made to reflect the risks involved with extended exposure to anesthetics and sedatives in children and pregnant women.
After treatment, there were marked decreases in visual analog scale (VAS)-pain, VAS-asthenia, severity of waking unrefreshed, tender point count, and Beck Depression Inventory.
The researchers observed a 47.5% increase in the percentage of participants who had a final pain score of 4 or less out of 10.
Even after loss of exclusivity, pregabalin has lower health care costs than gabapentin.
Kratom may be used to develop nonaddictive alternatives to opioids.
Alternative treatments include endomorphins, spinal cord stimulation, and psychotherapy.
Novice prescribers cited insufficient access to substance abuse counseling for patients, as well as insufficient access to more experienced prescribers, as reasons for not treating more patients.
Pain treatments often target either the brain or body, but data show that treatments often benefit both.
A patient with a baseline pain score of 60 on a scale of 0 to 100 would be expected to have a pain score of 45 after a non-acupuncture intervention; 35 after a sham acupuncture intervention; and 30 after true acupuncture.
Approaches such as acupuncture, massage, and tai chi may ease discomfort.
Opioid usage may exacerbate the problem.
Patients who underwent thoracic surgery were at the greatest risk of long-term opioid use.
A surprising number of patients already prescribed opioids were found to be abusing gabapentin.
The 6-month implant is more expensive than the pills, costing about $4,900 -- or more than $800 a month.
A restricted number of surgical procedures are not associated with increased incidence of chronic opioid use.
American medical school students spend much less time learning about pain than their international peers.
Much of the risk is related to cardiovascular complications, not overdoses.
This new form of treatment is designed to last 6 months.
There has been a 12 to 18% drop in opioid prescriptions since 2012.
Sleep disruption alters positive affective pain modulation.
An FDA committee will meet this week to review the risk-management plans.
The effects of the opioid-relapse prevention treatment waned after treatment discontinuation.
Twenty-five percent of doctors write month-long opioid prescriptions.
The new guideline is the latest in an overhaul designed to curb opioid abuse.
Revised labeling will occur across all types of opioids.
Some concerns include a lack of evidence underlying recommendations.
While mindfulness meditation has previously been associated with pain relief, the mechanistic action behind this has been unclear.
The new guidelines come in the wake of an opioid overdose epidemic in the U.S.
Targeted physicians prescribed 400% more controlled substances than their peers.
The FDA has accepted an NDA for Arymo ER (morphine sulfate; Egalet) extended-release tablets.
Those who presented with serious infections were more likely to currently be using opioids.
Functional MRI with central sensitization was found beneficial for selecting analgesics.
There were 18 893 deaths involving prescription opioids in the US in 2014.
Long duration of opioid use associated with new onset depression.
Odds of low levels increased with age and comorbidities.
More than 90% of patients with chronic pain continue to receive prescription opioids even after an overdose.
The most common symptom was headache, potentially resulting from the disease process, treatment, or comorbid conditions unrelated to RA.
Comorbid disease types appear to elevate dysfunction in the brain.
Despite data to the contrary, the study found that opioid prescribing is widespread.
Sleep deprivation impacts patient safety and quality of care.
The drug reverses the effects of rocuronium bromide and vecuronium bromide.
The drug can reverse the effects of opioid overdose in as little as 2 minutes.
Researchers have developed small, fully implantable devices that may one day be used to block pain signals before they reach the brain.
The pain thresholds of participants positively correlated with their opioid receptor availability.
Outpatient visits are what primarily drive costs.
A mean of 15 HD-tDCS sessions was found to reduce fibromyalgia pain by 50%.
The study looked at differences between fibromyalgia, lupus, and rheumatoid arthritis.
The findings suggest that anti-cytokine immunodeficiency may contribute to development of PHN.
An SCS system that delivered 10-kHz high-frequency therapy was nearly twice as effective at relieving pain as traditional low-frequency SCS.
Those taking opioids are less likely to receive guideline-recommended therapy.
The prevalence of prescription opioid use disorder grew from 2003 to 2013.
Mental disorders have been found to be predictors for the onset of chronic pain in adolescents.
Use of cannabis modestly reduced participants' pain scores.
The guidelines recommend that first responders be trained to use the opioid blocker naloxone.
A new report concluded that there is an unexpected link between two conditions that reorganize the brain: tinnitus and chronic pain.
Depression, substance abuse, and suicidal ideation are commonly reported in patients who have chronic pain.
How adolescents approach their chronic pain condition has an effect on how they will experience their condition in adulthood.
Commonly used antidepressants appear to target specific neurotransmitters in the brain that regulate chronic pain symptoms.
Corticosteroid injections were ineffective for people with spinal stenosis.
An intensive program of PT, OT, and psychotherapy significantly improved pain without the help of medication.
The FDA has approved labeling updates for Oxycontin extended-release tablets for patients aged 11 and older.
The report revealed that approximately 25.3 million adults had pain every day for the preceding 3 months.
The benefits of high-frequency stimulation were sustained over 12 months.
The task force hopes to develop protocols to curb abuse of opioids.
Chronic drinking only causes further deterioration, U.S. physicians warn.
In the HF10 therapy group, 85% of back pain and 83% of leg pain patients experienced a 50% reduction in pain or greater.
Researchers observed a dose-dependent reduction in pain in patients with diabetic peripheral neuropathy.
Many physicians don't ask about alternative therapies, so patients don't disclose them.
People with a history of smoking or abusing drugs are at the highest risk of using opioids for the long-term.
Notably, most healthy controls are also not meeting current recommendations for physical activity and steps.
Physicians, as well as patients, are unaware and misinformed of the dangers that come with opioid use
New oral naxalone sustained release (NSR) capsule allows for successful treatment of opioid-induced constipation.
Insurance companies may not cover the cost for hyperbaric oxygen therapy since it is not FDA-approved yet.
Napping is often used as a coping mechanism for people with fibromylagia.
Use of ultrasound guidance in interventional pain procedures is still lacking.
Animal models suggest that naloxone may be a potential microglia inhibitor, which can also impact the sleep-pain relationship.
In chronic pain patients, increased activation of microglia can cause depression and anxiety.
Nearly two-thirds of trials had one or more authors with financial conflicts of interest.
The researchers recommend that older adults be vaccinated to prevent long-term complications of shingles.
Women with fibromyalgia may benefit from hyperbaric oxygen therapy (HBOT).
The effects were also apparent in patients exposed to secondhand smoke.
Following a vegan diet helped lower levels of pain and promote weight loss in patients with diabetic neuropathy.
Patients with fibromyalgia had poorer health status, function, sleep, and faced higher costs.
TEAS treatment for 10 days cut rescue opioid requirement.
In addition to contributing significantly to cancer pain, researchers believe cancer progression depends largely on nerve activity.
About 15 trials of medical cannibinoids have been conducted worldwide, indicating effectiveness in reducing pain from cancer, diabetes, fibromyalgia, and neuropathy
While their are many benefits, researchers warn of the potential to create illegal drugs with the new pathway.
There was actually no difference in pain between the two groups.
High doses of the SNRI venlafaxine may alleviate depression and chronic pain in older patients.
Medical marijuana users still use more alcohol and drugs than the general population, but adding prescription pain meds does not increase this risk.
Imaging studies show that the brains of chronic pain patients differ from healthy control subjects.
Physical activity and fitness seem to have a positive effect on both the mental and physical characteristics of chronic pain.
The device relieves pain without the tingling sensation that often accompanies other existing pain-relief methods.
Since celiac is a possibly treatable condition, the authors suggest screening neuropathy patients for celiac disease.
Researchers have found a way to activate opioid receptors using light, creating a potential new way to treat pain.
Those already addicted may be seeking illicit narcotics as a substitute, contributing to the surge in heroin use.
Aerobic exercise intervention doesn't seem to change pain severity, but seemed to lessen pain interference in daily activities.
Research into the "wasabi receptor" could lead to new insights into pain.
Participants had lower levels of anxiety and depression, better mental quality of life, and had higher pain acceptance.
Many are unsure that the benefits of opioid use outweigh the burden of addiction.
Neurology Advisor Articles
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- Neural Targeting Spinal Cord Stimulation Superior for Axial Low Back Pain
- DHA Supplementation Has No Impact on IQ in Offspring
- Safinamide Approved as Adjunctive Therapy for Parkinson's
- International League Against Epilepsy Updates Epilepsy Classification System
- Depression, Schizophrenia Identified With Objective Blood Biomarker
- Autoimmune Disease Hospitalization Linked to Future Dementia Risk