Parkinson's Disease

Adjunct Medical Food Holds Benefits for Parkinson's Disease

Adjunct Medical Food Holds Benefits for Parkinson's Disease

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Previous animal model studies have shown PEA to be beneficial in neuroinflammation and provide neuroprotection.

Dizziness in Parkinson's May Be Caused by Cerebral Hypoperfusion

Dizziness in Parkinson's May Be Caused by Cerebral Hypoperfusion

Transcranial Doppler during head-up tilting may be useful for evaluating dizziness.

Parkinson's Disease Linked to Hepatitis B, C Infection

Parkinson's Disease Linked to Hepatitis B, C Infection

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People with HBV were 76% more likely and those with HCV were 51% more likely to develop PD than people in the comparison group.

Obstructive Sleep Apnea Affects Cognition in Parkinson's Disease

Obstructive Sleep Apnea Affects Cognition in Parkinson's Disease

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A significant association was found between the apnea-hypopnea index and Epworth Sleepiness Scale scores.

Novel Assay Identifies Parkinson's Disease Biomarker

Novel Assay Identifies Parkinson's Disease Biomarker

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Researchers have developed an assay that accurately identifies small quantities of α-synuclein in cerebrospinal fluid.

Regular Exercise Slows Decline Even in Advanced Parkinson's

Regular Exercise Slows Decline Even in Advanced Parkinson's

There were slower declines in health-related quality of life and mobility when exercise was increased by 30 minutes/week.

Safinamide Approved as Adjunctive Therapy for Parkinson's

Safinamide Approved as Adjunctive Therapy for Parkinson's

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The US FDA has approved safinamide as adjunctive therapy in Parkinson's disease to increase "on" time

Timed Light Therapy May Benefit Sleep in Parkinson's

Timed Light Therapy May Benefit Sleep in Parkinson's

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Improvements in excessive daytime sleepiness and daytime alertness were observed in the bright light therapy group.

Parkinsonian Disorder Differentiation Using Blood Biomarker

Parkinsonian Disorder Differentiation Using Blood Biomarker

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Neurofilament light chain, a blood biomarker, demonstrated high accuracy for distinguishing atypical parkinsonian disorders from Parkinson's disease.

Effect of Depression and Anxiety on Cognition in Parkinson's Disease

Effect of Depression and Anxiety on Cognition in Parkinson's Disease

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Comorbid psychological conditions affect cognitive function in Parkinson's disease, and treatment can be complicated by overlapping symptoms.

VIDEO: Dysfunctional Mitochondrial DNA May Play a Role in Parkinson's Disease

VIDEO: Dysfunctional Mitochondrial DNA May Play a Role in Parkinson's Disease

New findings suggest that dysregulation of mitochondrial DNA homeostasis may be a key factor in the pathogenesis of neuronal loss in people with Parkinson's disease.

Cognitive Stress Impacts Levodopa Efficacy in Parkinson's

Cognitive Stress Impacts Levodopa Efficacy in Parkinson's

During cognitive co-activation, the levodopa effect was significantly smaller.

FDA Reviewing Potential Treatment for Levodopa-Induced Dyskinesia

FDA Reviewing Potential Treatment for Levodopa-Induced Dyskinesia

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The FDA has accepted the NDA for ADS-5102 for the treatment of levodopa-induced dyskinesia (LID) in patients with Parkinson's disease.

Developing a Model for Predicting Cognitive Impairment in Parkinson's

Developing a Model for Predicting Cognitive Impairment in Parkinson's

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A combination of age and clinical scores better predicted cognitive impairment than age alone.

Adjunctive Safinamide Increases On Time in Parkinson's Disease

Adjunctive Safinamide Increases On Time in Parkinson's Disease

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Adjunctive treatment with safinamide helps increase "on" time in patients with Parkinson's disease.

Gene Mutation, Age Linked to Early-Onset Parkinson's Disease

Gene Mutation, Age Linked to Early-Onset Parkinson's Disease

Mutated GCH1 gene was associated with a 23% increased risk of Parkinson's disease, especially in men 50 years or younger.

More Evidence Favoring Inhaled Levodopa for Parkinson's

More Evidence Favoring Inhaled Levodopa for Parkinson's

A powdered version of the common treatment may help to relieve "off" periods.

Whole Body Vibration, Exercise May Improve Motor Performance In Parkinson's

Whole Body Vibration, Exercise May Improve Motor Performance In Parkinson's

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Pharmacologic intervention is the current standard of care for Parkinson's disease, yet medications frequently fail to control some symptoms, including tremor and postural instability.

GBA Mutations in Parkinson's May Increase Risk of Dementia

GBA Mutations in Parkinson's May Increase Risk of Dementia

The researchers found that GBA carriers were at greater risk for dementia and death (hazard ratios, 3.16 and 1.85, respectively) than non-carriers.

Statin Therapy Recommended in Parkinson's Patients With Vascular Risks

Statin Therapy Recommended in Parkinson's Patients With Vascular Risks

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Vascular disease can have a negative impact on cognition and motor phenotype in PD.

Cognitive Training, Transcranial Direct Current Stimulation Improves Cognition in Parkinson's

Cognitive Training, Transcranial Direct Current Stimulation Improves Cognition in Parkinson's

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Cognitive training and tDCS, alone or combined, appear to benefit cognition and QOL in Parkinson's patients

Gait Characteristics Better Predict Cognitive Decline in Early Parkinson's

Gait Characteristics Better Predict Cognitive Decline in Early Parkinson's

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The standard MoCA evaluation was unable to predict decline in fluctuating attention and visual memory.

Alternative Therapies Deemed Effective for Parkinson's Symptoms

Alternative Therapies Deemed Effective for Parkinson's Symptoms

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Over fifty percent of respondents reported using 1 or more alternative therapies.

4th World Parkinson Congress: What to Expect

4th World Parkinson Congress: What to Expect

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The 4th World Parkinson Congress takes September 20-23, 2016 in Portland, Oregon.

GBA Variants Predict Rapid Progression of Parkinson's Disease

GBA Variants Predict Rapid Progression of Parkinson's Disease

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The pathogenesis of GBA on PD is unclear, although several studies have pointed to disruptions of different molecular pathways that contribute to disease onset.

Beneficial Effect on Cognition Noted With Music Therapy in PD

Beneficial Effect on Cognition Noted With Music Therapy in PD

The potential role of active music therapy in ameliorating motor and nonmotor symptoms of Parkinson's disease (PD) was examined by researchers.

Statins May Protect Against Parkinson's Disease in Diabetes

Statins May Protect Against Parkinson's Disease in Diabetes

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All but one type of statin was associated with a dose-dependent neurprotective benefit against Parkinson's.

When It's Not Alzheimer's: The Differential Diagnosis of Dementia With Lewy Bodies

When It's Not Alzheimer's: The Differential Diagnosis of Dementia With Lewy Bodies

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According to a 2010 report based on a survey of caregivers of people with DLB, 78% of cases were initially misdiagnosed.

Leukemia Drug May Have Benefits for Parkinson's Disease

Leukemia Drug May Have Benefits for Parkinson's Disease

The drug was generally well-tolerated among study participants.

Traumatic Brain Injury Linked to Parkinson's, Lewy Body Pathology

Traumatic Brain Injury Linked to Parkinson's, Lewy Body Pathology

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Notably, there was no association found between TBI with LOC and dementia.

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