Pediatric Neurology

Early Autism Intervention Beneficial in At-Risk Kids

Early Autism Intervention Beneficial in At-Risk Kids

Infants at risk for autism do better if therapists train parents to communicate more effectively.

Migraine Linked to Fetal Growth Restriction in Men

Migraine Linked to Fetal Growth Restriction in Men

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Fetal growth restriction is characterized by a birthweight below the tenth percentile, according to gender and gestational age.

Buprenorphine Superior to Morphine in Neonatal Abstinence Syndrome

Buprenorphine Superior to Morphine in Neonatal Abstinence Syndrome

Sublingual buprenorphine was associated with shorter duration of treatment and shorter length of hospital stay.

Neurodevelopment Not Adversely Affected by Hydrocortisone Tx in Preemies

Neurodevelopment Not Adversely Affected by Hydrocortisone Tx in Preemies

No statistically significant differences between the groups in the distribution of patients without neurodevelopmental impairment were observed.

Pediatric Multiple Sclerosis Linked to Epstein-Barr, Herpes Simplex Virus Exposure

Pediatric Multiple Sclerosis Linked to Epstein-Barr, Herpes Simplex Virus Exposure

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Increased risk of pediatric multiple sclerosis was observed in patients with prior exposure to EBV, HSV-1, and vitamin D deficiency.

Iodide Supplementation May Not Benefit Preemies

Iodide Supplementation May Not Benefit Preemies

There was no significant difference in neurodevelopmental status at 2 years for infants with iodide vs placebo.

Cognitive Skills Adversely Affected by Thyroid Dysfunction

Cognitive Skills Adversely Affected by Thyroid Dysfunction

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Patients with subclinical hypothyroidism scored worse on tests of processing speed than patients with normal thyroid function.

Exploring Links Between Zika, GBS, Microcephaly in Brazil

Exploring Links Between Zika, GBS, Microcephaly in Brazil

There was an apparent resurgence of Zika virus and GBS early in 2016, but no subsequent increase in microcephaly.

Q&A: Strategies for Transitioning Pediatric Patients to Adult Care

Q&A: Strategies for Transitioning Pediatric Patients to Adult Care

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The transition process can be challenging for patients and families, requiring a great deal of preplanning by providers.

Valproate for Epilepsy Poses Greater Risk for Major Congenital Malformations

Valproate for Epilepsy Poses Greater Risk for Major Congenital Malformations

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Lamotrigine and carbamazepine may represent safer treatment alternatives for girls and women who are or who might become pregnant.

DHA Supplementation Has No Impact on IQ in Offspring

DHA Supplementation Has No Impact on IQ in Offspring

No between-group differences in measures of language, academic, or executive functioning were observed in those who took DHA during pregnancy and those who did not.

Movement Disorder After Foreign Body Ingestion

Movement Disorder After Foreign Body Ingestion

A 10-month-old girl admitted to PICU with sudden onset of movement disorder was found to have ingested a foreign body.

Aptiom Aims for Pediatric Indication for Partial Onset Seizures

Aptiom Aims for Pediatric Indication for Partial Onset Seizures

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Sunovion has filed a supplemental NDA with the FDA to expand the indication for Aptiom to pediatric patients with partial onset seizures.

Pediatric Migraine Relief With Sphenopalatine Ganglion Block

Pediatric Migraine Relief With Sphenopalatine Ganglion Block

Improvements in migraine pain were reported in as little as 10 minutes after the nerve block.

Autism Spectrum Disorder Linked to Sex-Based Cortical Thickness

Autism Spectrum Disorder Linked to Sex-Based Cortical Thickness

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Female participants with phenotypic male neuroanatomical features had an increased risk for autism spectrum disorder.

Risk of Zika Virus-Related Birth Defects in Pregnant Women

Risk of Zika Virus-Related Birth Defects in Pregnant Women

The CDC report only accounts for physical birth defects, as researchers note that the full scope of developmental defects has yet to be recorded.

Vigabatrin Dose Affects Risk for Brain Abnormalities in Infantile Spasms

Vigabatrin Dose Affects Risk for Brain Abnormalities in Infantile Spasms

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There is as much as a 32% risk for vigabatrin-associated brain abnormalities in patients with infantile spasms.

Treating Pediatric Chronic Migraine With Cognitive Behavioral Therapy, Amitriptyline

Treating Pediatric Chronic Migraine With Cognitive Behavioral Therapy, Amitriptyline

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A larger percentage of participants receiving CBT plus amitriptyline reached a 50% reduction in migraine frequency during treatment compared with HE plus amitriptyline.

Comorbid Headache, Stroke Common in Pediatric Patients

Comorbid Headache, Stroke Common in Pediatric Patients

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The co-presentation of headache at stroke onset in children may provide clues to underlying pathophysiologic mechanisms.

Persistent Asthma May Increase Migraine Risk in Children

Persistent Asthma May Increase Migraine Risk in Children

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Persistent asthma was found to be associated with an increased frequency of migraine.

Antiretroviral Therapy May Improve Neurodevelopmental Outcomes in HIV-Infected Infants

Antiretroviral Therapy May Improve Neurodevelopmental Outcomes in HIV-Infected Infants

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Early detection and robust treatment are critical to limiting deficits in achieving developmental milestones in HIV-infected infants.

MRI Improves Diagnostic Accuracy of Fetal Brain Abnormalities

MRI Improves Diagnostic Accuracy of Fetal Brain Abnormalities

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In addition to ultrasonography, MRI improved diagnostic accuracy and had an impact on prognoses in cases of fetal brain abnormalities.

Location of Childhood Arterial Ischemic Stroke Influences Recurrence

Location of Childhood Arterial Ischemic Stroke Influences Recurrence

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The difference in rate of recurrence of PCAIS may have to do with a difference in mechanism compared with ACAIS.

Migraine Linked to Adverse Events in Pregnancy

Migraine Linked to Adverse Events in Pregnancy

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Migraine in pregnancy may warrant early referral to a neurologist and more intensive surveillance as a result of increased adverse birth events.

Neonatal Hemorrhagic Stroke: Prevalence and Outcomes

Neonatal Hemorrhagic Stroke: Prevalence and Outcomes

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Despite being more common than thought, many cases of neonatal hemorrhagic stroke remain idiopathic.

Cognitive Behavioral Therapy Effective for Pediatric Migraine

Cognitive Behavioral Therapy Effective for Pediatric Migraine

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Cognitive behavioral therapy provides sustained relief from pediatric migraine with few to no adverse effects.

Maternal Antiepileptic Use and Risk for Major Congenital Malformations in Offspring

Maternal Antiepileptic Use and Risk for Major Congenital Malformations in Offspring

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A diagnosis of maternal epilepsy alone was not associated with an increase in congenital malformations in offspring.

MRI May Help Detect White Matter Injury in Neonates

MRI May Help Detect White Matter Injury in Neonates

The assessments revealed that damage in the frontal lobes mattered more than damage in other brain locations.

No Difference in Neurodevelopment in Children Conceived by Assisted Reproduction

No Difference in Neurodevelopment in Children Conceived by Assisted Reproduction

Researchers found no difference in neurodevelopment in children conceived by ART.

Neonatal Abstinence Syndrome Linked to Poor Academic Performance

Neonatal Abstinence Syndrome Linked to Poor Academic Performance

Test scores for children with NAS, on average, were sharply lower than those of both groups of children.

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