Pediatric Neurology

Caffeine Therapy for Apnea of Prematurity Safe Over Long Term

Caffeine Therapy for Apnea of Prematurity Safe Over Long Term

Neonatal caffeine therapy for apnea of prematurity has no detrimental long-term effects and even improves some neurologic measures.

Extremely preterm children more likely to develop motor impairment

This prospective cohort study showed that children born extremely premature or at an extremely low birth weight were more likely to develop cerebral palsy or non-CP motor impairment at 8 years' corrected age when compared to matched controls born at term.

Isolated vomiting not linked to clinically important TBI in children

Isolated vomiting was not associated with clinically important TBI or evidence of TBI on computed tomography scans among pediatric patients with head injury.

Psychosis Could Be a Potential Side Effect of Steroid Treatment in Kids

Psychosis Could Be a Potential Side Effect of Steroid Treatment in Kids

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Iatrogenic steroid-induced psychosis is a rare side effect of glucocorticoid therapy which is mostly seen in adults, although it has been reported in children and adolescents.

Prenatal Exposure to SSRI Tied to Fetal Brain Development

Prenatal Exposure to SSRI Tied to Fetal Brain Development

Prenatal exposure to a selective serotonin reuptake inhibitor is associated with fetal brain development.

White Matter Tracts Differ for Infants With Fragile X Syndrome

White Matter Tracts Differ for Infants With Fragile X Syndrome

There are significant differences in the development of 12 fiber tracts between infants with fragile X syndrome and controls.

Early-Life Epilepsy Should Be Urgently Treated With EBM

Early-Life Epilepsy Should Be Urgently Treated With EBM

Best diagnostics and evidence-based treatments should be used from the start of the disease.

Early Infection With Zika Virus Associated With More Birth Defects in Pregnancy

Early Infection With Zika Virus Associated With More Birth Defects in Pregnancy

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Among pregnant women with Zika virus infection, birth defects were reported more often in fetuses and infants whose mothers had been infected with the virus early in their pregnancies.

Traumatic Brain Injury Rare for Children With Isolated Vomiting

Traumatic Brain Injury Rare for Children With Isolated Vomiting

Children presenting with head injury with isolated vomiting rarely have clinically important TBI.

First-in-Class Inhibitor Designated Orphan Drug for Spinal Muscular Atrophy

First-in-Class Inhibitor Designated Orphan Drug for Spinal Muscular Atrophy

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By inhibiting the activation of myostatin, SRK-015 may promote a clinically meaningful increase in muscle mass and strength.

Improving Cognitive Outcomes in Preemies an Uphill Battle

Improving Cognitive Outcomes in Preemies an Uphill Battle

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Preventive strategies for reducing the high incidence of bronchopulmonary dysplasia may be key to the improvement of long-term outcomes in EP/VP children.

Later-Onset Spinal Muscular Atrophy Benefits From Nusinersen

Later-Onset Spinal Muscular Atrophy Benefits From Nusinersen

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Improved motor function was observed among more participants in the nusinersen group compared with those in the control group.

Newborns With Neonatal Abstinence Syndrome May Benefit From Rooming-In vs NICU Care

Newborns With Neonatal Abstinence Syndrome May Benefit From Rooming-In vs NICU Care

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Rooming-in with the mother or family members may help reduce pharmacotherapy and increase breastfeeding in newborns with NAS.

Cognitive Deficits Apparent in Pediatric Chronic Kidney Disease

Cognitive Deficits Apparent in Pediatric Chronic Kidney Disease

Children with chronic kidney disease may have deficits in global and domain-specific cognition.

Fetal alcohol spectrum disorders likely to be vastly underdiagnosed in US

A multi-site, cross-sectional study found a large mismatch between previously diagnosed fetal alcohol spectrum disorders and the actual prevalence of cases identified.

Prevalence of Fetal Alcohol Syndrome in the US

Prevalence of Fetal Alcohol Syndrome in the US

Fetal alcohol syndrome prevalence ranges from 1.1% to 5.0% among first graders in 4 US communities.

Significant Head Injury Reported in 7 Percent of Children: CDC

Significant Head Injury Reported in 7 Percent of Children: CDC

Less than 10% of boys and girls aged 3-17 have ever had a significant head injury in 2016.

Ketamine, Propofol Help Reduce Recovery Time in Children Undergoing Sedated MRI

Ketamine, Propofol Help Reduce Recovery Time in Children Undergoing Sedated MRI

For children undergoing MRI with deep sedation, a shorter recovery time is associated with use of ketamine at induction followed by propofol infusion.

FDA Expands Pediatric Age Range for Contrast Agent

FDA Expands Pediatric Age Range for Contrast Agent

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The FDA has approved an expanded age range for MultiHance contrast agent.

Nutrients Key to Neurodevelopment in Child's First 3 years

Nutrients Key to Neurodevelopment in Child's First 3 years

Providing adequate nurtrients during a child's first 3 years is important for optimal neurodevelopment.

No long-term neurodevelopmental effects of inhaled budesonide in preterm infants

Budesonide used for prevention of bronchopulmonary dysplasia in extremely preterm infants showed no difference in rate of neurodevelopmental disability at two years compared to placebo treated infants.

Herpes simplex virus infection uncommon in infants undergoing meningitis evaluation

Through this retrospective study, researchers found that 0.42% of study infants undergoing CSF culture for suspected meningitis tested positive for herpes simplex virus (HSV) infection.

Neurodevelopment in Preemies Not Affected by Glucocorticoid Therapy

Neurodevelopment in Preemies Not Affected by Glucocorticoid Therapy

There is no increased rate of neurodevelopmental disability in preterm infants using inhaled glucocorticoids.

Language Delay May Be Linked to Prenatal Acetaminophen Use

Language Delay May Be Linked to Prenatal Acetaminophen Use

A language delay among girls is linked to acetaminophen use during pregnancy.

Fetal MRI Analysis, Machine Learning Identifies Candidates for CSF Diversion

Fetal MRI Analysis, Machine Learning Identifies Candidates for CSF Diversion

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Multiple imaging characteristics from fetal MRI analysis helped to yield a model with the ability to classify postnatal CSF diversion status with a high level of accuracy.

Folate Supplementation May Help Reduce Autistic Traits in Children Exposed to AEDs In Utero

Folate Supplementation May Help Reduce Autistic Traits in Children Exposed to AEDs In Utero

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Children who are exposed to AEDs in utero may have a reduced risk of autistic traits.

Identifying Pediatric Seizures With Hemispheric Regional Cerebral Oxygen Saturation

Identifying Pediatric Seizures With Hemispheric Regional Cerebral Oxygen Saturation

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The findings further the utility of cerebral oximetry as a neurological assessment tool.

Fingolimod Wins Breakthrough Designation for Pediatric Multiple Sclerosis

Fingolimod Wins Breakthrough Designation for Pediatric Multiple Sclerosis

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The FDA has granted Breakthrough Therapy designation to Fingolimod for treating children with relapsing multiple sclerosis.

Identifying Risk of Stroke Following Traumatic Injury

Identifying Risk of Stroke Following Traumatic Injury

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Investigators sought to assess the risk of ischemic stroke after a traumatic injury in patients <50 years of age.

Effect of Maternal Antibiotic Use on Neonatal Seizure Risk

Effect of Maternal Antibiotic Use on Neonatal Seizure Risk

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Researchers from the University of Colorado reported on whether or not maternal antibiotic use during labor increased the risk of seizure for the neonate.

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