Gestational exposure to folic acid fortification is associated with cortical development.
Investigators sought to investigate the association between the use of diethylstilbestrol during pregnancy on risk for ADHD in subsequent generations.
Food insecurity may be linked to behavioral problems and poorer cognitive performance in children.
Early preterm birth is associated with a higher level of ADHD symptoms in preschool children.
In multivariate analyses, adverse late cranial ultrasound findings were an independent risk factor for full scale IQ scores.
A meta-analysis of 18 studies examining the association of prenatal antidepressant exposure with motor development in children showed a small overall effect of worse motor development outcomes among children exposed to antidepressants in pregnancy.
Neuroblastoma survivors are at elevated risk for psychological impairment.
Since MRI and EEG risk factors were retrospectively reviewed, the study was unable to analyze the temporal seizure burden or the volume of MRI injury, both of which may have provided greater insights into outcomes.
No significant association among closing pressure, amount of CSF removed, and time to resolution of papilledema is reported in patients with PTCS.
There are considerable gaps in knowledge relating to the effectiveness of non-pharmacologic treatments for ADHD in pediatric patients.
A study evaluated the long-term adverse effects of maternal depression on child development.
The Agency has received reports of serious neural tube birth defects involving the brain, spine, and spinal cord in babies born to women who received dolutegravir for HIV treatment.
Congenital Heart Disease, Hispanic Ethnicity Associated With Increased Mortality in Pediatric Arterial Ischemic StrokeMay 21, 2018
The investigators were unable to determine which type of congenital heart disease or which type of ventricular assist device, if used, played a role in mortality outcomes.
Children hospitalized for traumatic brain injury tend to have unmet needs for educational and rehabilitation services approximately 2 years after a traumatic brain injury event.
Childhood cancer survivors frequently have clinical abnormalities attributable to peripheral neuropathy.
Children with prenatal exposure to serotonin reuptake inhibitors have better executive function at age 12 years.
The FDA's decision was based on data from the Phase 3 PARADIGMS study (N=215) which evaluated the safety and efficacy of oral fingolimod vs interferon beta-1a injection in pediatric patients aged 10 to <18 years with relapsing MS.
Greater sugar consumption during pregnancy and early childhood may adversely impact child cognition.
Previous studies have shown that delayed-release DMF is safe and effective in treating RRMS in adult patients. The goal of this study was to extend these analyses to evaluate DMF in pediatric patients with RRMS.
Ventriculomegaly, Polymicrogyria Predict Epilepsy Risk Among Pediatric Patients With Cytomegalovirus InfectionsMay 04, 2018
Investigators retrospectively reviewed the patients' medical records and MRI images and assessed the associations between the MRI findings and neurologic outcomes, specifically neurodevelopmental achievement, epilepsy, and sensorineural hearing loss.
A team of investigators assessed the effect of intravenous administration of methylprednisolone on duration of episodes in adolescent and young adult patients with Kleine-Levin syndrome.
Researchers conducted post-hoc analysis of data derived from 2 randomized, placebo-controlled trials to determine the safety and tolerability of eslicarbazepine in pediatric patients with partial-onset seizures not responsive to treatment with ≤2 antiepileptic drugs.
Neonatal caffeine therapy for apnea of prematurity has no detrimental long-term effects and even improves some neurologic measures.
This prospective cohort study showed that children born extremely premature or at an extremely low birth weight were more likely to develop cerebral palsy or non-CP motor impairment at 8 years' corrected age when compared to matched controls born at term.
Isolated vomiting was not associated with clinically important TBI or evidence of TBI on computed tomography scans among pediatric patients with head injury.
Iatrogenic steroid-induced psychosis is a rare side effect of glucocorticoid therapy which is mostly seen in adults, although it has been reported in children and adolescents.
Prenatal exposure to a selective serotonin reuptake inhibitor is associated with fetal brain development.
There are significant differences in the development of 12 fiber tracts between infants with fragile X syndrome and controls.
Best diagnostics and evidence-based treatments should be used from the start of the disease.
Among pregnant women with Zika virus infection, birth defects were reported more often in fetuses and infants whose mothers had been infected with the virus early in their pregnancies.
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