Seizures

Some Antiepileptic Drugs Associated With Increased Risk for Toxic Epidermal Necrolysis

Some Antiepileptic Drugs Associated With Increased Risk for Toxic Epidermal Necrolysis

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New use of clonazepam, levetiracetam, or topiramate was not associated with Stevens-Johnson syndrome and toxic epidermal necrolysis.

Eclampsia Linked to Higher Relative Risk of Seizure Disorder

Eclampsia Linked to Higher Relative Risk of Seizure Disorder

The relative risk of seizure disorder is higher in women who were affected by eclampsia than those who were not.

FDA Approves Lacosamide for Pediatric Partial-Onset Seizures

FDA Approves Lacosamide for Pediatric Partial-Onset Seizures

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The FDA has approved lacosamide for treating pediatric patients with partial-onset seizures.

Cannabidiol Product Concentration Varies in Products Sold Online

Cannabidiol Product Concentration Varies in Products Sold Online

Of 84 products sampled, 42.85% were underlabeled and 26.19% were overlabeled.

Development of Guillain-Barré Syndrome Associated With Zika Virus Infection

Development of Guillain-Barré Syndrome Associated With Zika Virus Infection

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Infection with the Zika virus may increase the risk for development of Guillain-Barré syndrome.

Surgery Reduces Seizures in Treatment-Refractory Epilepsy

Surgery Reduces Seizures in Treatment-Refractory Epilepsy

Surgery can improve freedom from seizures in pediatric patients with drug-resistant epilepsy.

Infant Respiratory Distress Syndrome Increases Childhood Epilepsy Risk

Infant Respiratory Distress Syndrome Increases Childhood Epilepsy Risk

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Infants born at 32-36 weeks gestation from 1978-2008 with infant respiratory distress syndrome were enrolled to evaluate the long term risk of epilepsy.

Posttraumatic Epilepsy: Understanding Risk, Severity, and Outcomes

Posttraumatic Epilepsy: Understanding Risk, Severity, and Outcomes

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Risk for mortality in posttraumatic epilepsy is high, and negative outcomes affecting cognitive, affective, and physical function are common.

Model Helps Identify Seizure Risk in Critically Ill

Model Helps Identify Seizure Risk in Critically Ill

A model comprising 6 variables can identify the probability of seizure for critically ill patients.

Antiepileptic Drugs Linked to Impaired Bone and Muscle Development in Children

Antiepileptic Drugs Linked to Impaired Bone and Muscle Development in Children

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Previous research found an association between AED use and reduced bone density in adults.

Dose "Ceiling" May Exist for Epilepsy Treated With Lamotrigine

Dose "Ceiling" May Exist for Epilepsy Treated With Lamotrigine

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A "ceiling" may exist for lamotrigine therapy above which remission from seizures may be unlikely.

FDA Approves Vagus Nerve Stimulator for Refractory Epilepsy

FDA Approves Vagus Nerve Stimulator for Refractory Epilepsy

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The system includes a detect-and-respond mode, which is designed to prevent seizures before they start and deliver therapy to stop them if they do.

Epilepsy in the US: A Growing Public Health Concern

Epilepsy in the US: A Growing Public Health Concern

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The CDC has updated the US national estimate of epilepsy prevalence and estimates 3.4 million people are affected by epilepsy.

Seizures More Likely in Patients With Sepsis Than General Population

Seizures More Likely in Patients With Sepsis Than General Population

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Patients with sepsis included in this analysis may have presented with other CNS pathologies that could have contributed to seizure risk.

Incidence of Seizures and Epilepsy High in Ischemic Stroke

Incidence of Seizures and Epilepsy High in Ischemic Stroke

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Newer antiepileptic drugs were associated with fewer adverse effects in patients with ischemic stroke.

Antiepileptic Drugs Increase Risk of Birth Complications, Poor Fetal Health

Antiepileptic Drugs Increase Risk of Birth Complications, Poor Fetal Health

Pregnant women on antiepileptic drugs are at a higher risk of giving birth to a premature and SGA infant.

FDA Approves Expanded Seizure Indication for Aptiom

FDA Approves Expanded Seizure Indication for Aptiom

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The FDA has approved an expanded indication for Aptiom to treat pediatric partial-onset seizures.

FDA Approves Briviact for Partial-Onset Seizure Monotherapy

FDA Approves Briviact for Partial-Onset Seizure Monotherapy

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Briviact was initially approved as adjunct treatment for partial-onset seizures.

Buccal, Nasal Midazolam Most Cost-Effective for Pediatric Status Epilepticus

Buccal, Nasal Midazolam Most Cost-Effective for Pediatric Status Epilepticus

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Rectal diazepam is currently the only FDA-approved treatment for pediatric status epilepticus.

Epilepsy Incidence Rates on the Rise in US Adults

Epilepsy Incidence Rates on the Rise in US Adults

Over 1% of the US population reported active or current epilepsy in 2015.

Cannabidiol May Impact Antiepileptic Drug Levels in Refractory Epilepsy

Cannabidiol May Impact Antiepileptic Drug Levels in Refractory Epilepsy

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While several studies have demonstrated efficacy in refractory epilepsy, it is still not clear how cannabidiol may have an impact on current epilepsy treatments.

Brexanolone Safe, Tolerable as Adjunctive Therapy in Super-Refractory Status Epilepticus

Brexanolone Safe, Tolerable as Adjunctive Therapy in Super-Refractory Status Epilepticus

Brexanolone may help wean patients with super-refractory status epilepticus off of third-line agents.

Review Supports Current NICE Guidelines for Tx of Partial Onset Seizures

Review Supports Current NICE Guidelines for Tx of Partial Onset Seizures

For people with seizures, levetiracetam is more effective than carbamazepine and lamotrigine.

Genetic Testing Justified in Early Childhood Epilepsy

Genetic Testing Justified in Early Childhood Epilepsy

In children with epilepsy, genetic investigation that emphasizes sequencing tests should be part of the initial evaluation.

Epilepsy Diagnosis, Outcomes Associated With Depression Severity

Epilepsy Diagnosis, Outcomes Associated With Depression Severity

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Previous research has found a higher prevalence of depression before and after an epilepsy diagnosis.

Vagus Nerve Stimulation Therapy for Epilepsy: FDA Expands Age Range

Vagus Nerve Stimulation Therapy for Epilepsy: FDA Expands Age Range

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The FDA has expanded the age range for the VNS Therapy system.

Partial-Onset Seizure Treatment Discontinued

Partial-Onset Seizure Treatment Discontinued

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Potiga tablets have been discontinued due to the limited use of the medicine.

Case Study: Headache, Confusion, and Seizures in Patient With SLE

Case Study: Headache, Confusion, and Seizures in Patient With SLE

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Woman with SLE complains of headache, confusion, and mild somnolence to the emergency department.

Evaluating the Bioequivalence of Generic Lamotrigine for Epilepsy

Evaluating the Bioequivalence of Generic Lamotrigine for Epilepsy

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The FDA-sponsored study sought to evaluate the bioequivalence of 2 generic forms of the popular epilepsy treatment lamotrigine.

Undetected Seizures May Play a Role in Alzheimer's Pathology

Undetected Seizures May Play a Role in Alzheimer's Pathology

Epileptic phenomena are an important component of the dysfunction of the neuronal networks affected by Alzheimer's disease.

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