In patients with lorazepam-resistant status epilepticus, treatment with lacosamide had comparable efficacy and safety as sodium valproate.
The International League Against Epilepsy has revised its epilepsy classification system in an effort to inform epilepsy research and aid drug development.
Sunovion has filed a supplemental NDA with the FDA to expand the indication for Aptiom to pediatric patients with partial onset seizures.
Elderly patients with neurologic comorbidities such as stroke or dementia had an increased risk for epilepsy or seizures.
Patients taking enzyme-inducing antiepileptic drugs and hormonal contraceptives face a greater risk of unintended pregnancy.
Participants reported improved adherence to a modified Atkins diet compared with the popular but restrictive ketogenic diet.
This study identified a feature of the epileptic brain that evolves slowly and differs fundamentally in well-controlled and poorly controlled epilepsy.
A diagnosis of maternal epilepsy alone was not associated with an increase in congenital malformations in offspring.
Patients with both MS and epileptic seizures had a younger age at onset of MS compared with those without seizures.
Functional MRI may provide a less-invasive option for evaluating memory function in patients undergoing epilepsy surgery.
Brain oxygenation may be compromised during periodic discharges, ultimately warranting treatment.
Nearly 60% of patients had achieved seizure freedom at last follow-up, 10 to 21 years after surgery.
Careful monitoring of EEG patterns is a useful way to stratify seizure risk in critically ill patients.
Beate Diehl, MD, PhD, FRCP, discusses her research on post-stroke epilepsy.
Shaun Hussain, MD, MS, discusses a gap in health care provider knowledge that may contribute to the delay in the diagnosis and treatment of infantile spasms.
Elizabeth Thiele, MD, PhD discusses results from her research on cannabidiol in Lennox-Gastaut syndrome.
Clobazam had been previously identified as an AED with a significant interaction with CBD.
Justin Gover, CEO of GW Pharmaceuticals, the parent company of Greenwich Biosciences, discusses the status of the company's cannabidiol product Epidiolex on the heels of positive results from several placebo-controlled trials in epileptic syndromes.
Number of AEDs and seizure frequency also influenced depression in people with epilepsy.
Concordant EEG/fMRI and ESI predicted outcomes with 100% sensitivity and specificity.
Adjunctive everolimus treatment has been found to significantly reduce frequency of treatment-resistant seizures in TSC.
The triple-validated SeLECT score may help identify patients suited for antiepileptic drug trials.
Results of the phase 3, placebo-controlled trial support previous findings from an expanded-access program.
Brain Atrophy May Help Predict Surgical Outcomes in Mesial Temporal Lobe Epilepsy With Hippocampal SclerosisDecember 04, 2016
Atrophy in areas outside of the MTLE-HS network may predict poor surgical outcomes.
Less than 30% of patients were seen by an effective provider within 1 week of onset of infantile spasms.
Half of patients experienced a reduction in seizure frequency after statin initiation.
Awareness of the effects of polypharmacy on patient well-being is an important component of care.
Patients taking cannabidiol experienced a significant reduction in drop seizures compared with placebo.
Michael Privatera, MD, AES president spoke with Neurology Advisor about some of the key topics and presentations slated for this year's meeting.
Veterans with epilepsy could benefit from evidence-based chronic disease self-management programs that target physical and psychiatric comorbidities.
Neurology Advisor Articles
- New Sleep Apnea Clinical Practice Guidelines
- International League Against Epilepsy Updates Epilepsy Classification System
- In Refractory Status Epilepticus, Lacosamide May Be a Good Option
- Patent Foramen Ovale Closure Reduces Stroke Risk in Patients With Inherited Thrombophilias
- The Handoff: Your Week in Neurology News - 3/23/17
- Q&A: Strategies for Transitioning Pediatric Patients to Adult Care
- Epilepsy Risk May Increase After Incident Depression
- Alzheimer's Caregiver Coping Program Does Not Increase Health Care Costs
- Valproate for Epilepsy Poses Greater Risk for Major Congenital Malformations
- VTE Recurrence Decreased With Rivaroxaban