Stroke News Archive
Results at 3 years for tenecteplase vs placebo in patients with intermediate-risk pulmonary embolism.
Recurrent fatal or nonfatal VTE occurred in 1.5% of patients who took 20 mg of rivaroxaban, 1.2% of patients who took 10 mg, and 4.4% who took aspirin.
Patients with inherited thrombophilias who did not undergo patent foramen ovale closure faced a significantly increased risk of stroke.
More than 80% of ischemic stroke patients weren't getting adequate anticoagulation therapy.
Up to 20% of stroke cases in young adults occur in those with cervical artery dissection, the leading cause of stroke in this population.
Clinicians should closely monitor patients with atrial fibrillation, especially if they are female and of increasing age.
Efficacy of triple antiplatelet therapy compared with current guideline-based therapy for the prevention of recurrent stroke was evaluated in the TARDIS trial.
The increase in usage of antithrombotics, especially vitamin K antagonists, has been linked to an increase in prevalence of subdural hematomas.
More patients receiving VNS experienced enhanced arm movement over a 90-day period.
Restarting anticoagulation after both nonlobar and lobar ICH was associated with decreased mortality.
Men were more likely than women to be treated with IV tPA within 30 minutes of arrival at a hospital.
As more patients survive ICH, emphasis is slowly shifting from survival to improving ICH-related morbidity and optimization of functional recovery.
The results provide good evidence for the use of contact aspiration in ischemic stroke.
Optimal antiplatelet treatment has yet to be determined for stroke survivors with prior intracerebral hemorrhage.
The co-presentation of headache at stroke onset in children may provide clues to underlying pathophysiologic mechanisms.
Psychological distress may cause changes within cells that trigger inflammation and oxidative stress, both of which are believed to increase stroke risk.
Delays related to the determination of treatment eligibility increased door-to-needle times by more than 30 minutes compared with patients with no delays.
Pulmonary embolism risk was lowest in patients with cerebral venous thromboembolism during the index hospitalization.
Neither lying flat nor sitting up appears to alter outcomes in patients presenting with acute stroke.
Among ICH survivors, 63% developed both depression and dementia during a 5-year follow-up study.
Standardized definitions were proposed for stroke, hypoxic-ischemic injury, and cerebral hemorrhage.
Early intervention in patients with heart failure or atrial fibrillation may help delay or prevent the onset of mild dementia.
Patients receiving treatment with vitamin K antagonists (VKA) or antiplatelet agents face a significantly increased risk of mortality within 24 hours of intracranial hemorrhage.
The difference in rate of recurrence of PCAIS may have to do with a difference in mechanism compared with ACAIS.
Use of advanced imaging may help predict which patients will have an optimal response to treatment with intravenous tissue plasminogen activator.
It is not clear if identifying atrial fibrillation in an effort to prevent stroke would be an effective preventive strategy.
Despite being more common than thought, many cases of neonatal hemorrhagic stroke remain idiopathic.
The use of combined hormonal contraceptives significantly increases the risk of ischemic stroke in women with migraine with aura but not in women with migraine without aura.
Migraine affects approximately 20% of the general population and is associated with an increased risk for ischemic stroke.
The increased risk of stroke was only observed among patients with diabetes controlled by insulin.
Using telestroke to evaluate patients with acute ischemic stroke eligible for thrombolysis provided access to acute stroke care in underserved areas.
A significant inverse trend was observed between the Healthy Nordic Food Index and risk of stroke.
Patients with elevated levels of activity in the amygdala were at higher risk for cardiovascular events.
Intravenous thrombolysis prior to mechanical thrombectomy did not benefit patients with acute ischemic stroke due to a large vessel occlusion.
Warfarin protected against ischemic stroke, major bleeding, and all-cause mortality in patients who continued to take the drug after dementia diagnosis.
Streptococcus mutans may raise the risk of cerebral microbleeds and stroke.
Concomitant use of oral anticoagulants contributed to a significantly higher increased risk for ICH.
Risk of stroke is greatest in the first 2 days after the intervention, then gradually decreases.
At 1 year, no difference in complications was observed between the 2 age groups.
Twelve months after AFib ablation, risk of recurrent stroke or AFib is low.
Beate Diehl, MD, PhD, FRCP, discusses her research on post-stroke epilepsy.
The triple-validated SeLECT score may help identify patients suited for antiepileptic drug trials.
Patients with lesions in the left basal ganglia were more likely to have post-stroke epilepsy.
Women with a history of migraine headache had a more than 2-fold increased risk of stroke over a 6-year follow-up period.
Recent research found benefits in outcome outweighed any increase in hemorrhagic complications in patients with large infarcts.
CT scans may guide the decision to use thrombolysis in patients with unknown time of stroke onset.
Warfarin-linked reduction in VTEis attenuated after accounting for competing death events.
Only 46% of patients with indications received OACs at discharge from the hospital.
The effect of antihypertensive drugs and stains on cognition is uncertain.
32.1% believed that heart attack is a major risk factor of AF, which is incorrect.
Another class of antacids, H2 receptor antagonists, had no impact on stroke risk.
Serious adverse events, especially those requiring hospitalization, may indicate an elevated risk of stroke.
The neuroprotective effect was evident after at least 6 months of use.
Pregnancy is a major risk factor for stroke in younger women, but not in older women.
Notably, the location of ICH influenced the association with hematoma volume and growth in patients with prior antiplatelet use.
Careful evaluation is required to rule out any other known causes of stroke in patients with PFO.
Risks associated with certain NSAIDS and steroids warrant further investigation.
Out of 34 cases of MRI-detected fetal stroke, ultrasound was only able to identify 5 cases.
Long episodes of AT/AF were more likely to be associated with clinical events than short episodes.
In the future, hs-cTnT may be a possible risk marker upfront of treatment decisions, especially in patients combined with detected CMBs.
The study was underpowered to detect differences in all-cause mortality and stroke.
Patients with untreated OSA face an increased risk of complications.
Although the study did not demonstrate efficacy of glyburide, differences were seen in the amount midline shift at 3-4 days.
A committee from the American Heart Association failed to make specific clinical recommendations for the management of hypertension related to cognitive impairment.
Preventable causes include dehydration, heart failure, pneumonia, and UTIs.
Patients with acute ischemic stroke experienced less disability when treated with early endovascular thrombectomy.
Cerebral microbleeds increase the risk for symptomatic ICH after thrombolysis for acute ischemic stroke.
At baseline, 83% of the patients had established cardiovascular disease, chronic kidney disease, or both.
Strategies to decrease risk of contracting varicella zoster virus need to be addressed in populations with autoimmune disease.
Ninety-seven percent of people who received CCFES reported improved use of their hands.
Being overweight may slightly lower chances for hemorrhagic stroke, the study found.
The Trevo devices are the first to be indicated for use in conjunction with IV tPA.
Lower serum calcium levels correlate with risk of hematoma expansion in intracerebral hemorrhage.
The researchers noted that CPAP users may not be using the device long enough to see benefits for their cardiovascular health.
Studies have linked GCA with increased risk of VTE; however, results have been compromised by limited data sets.
Doctors should be monitoring for high blood pressure and cholesterol in this patient population.
Four blood biomarkers are associated with an increased risk of ischemic stroke.
In mice, the protein triggered the stem cells to become functioning neurons.
Women who received calcium supplementation were at a greater risk for dementia and dementia with stroke.
Associations with increased mortality were found for both low and high hemoglobin levels, suggesting a U-shaped relationship.
Weaker handgrip was also associated with an elevated risk of stroke.
Both lesion count and volume was less in the treatment group vs controls.
Several studies have also suggested that sleep-wake disorders may also negatively impact neuroplasticity and stroke recovery.
Despite 3 large randomized trials and updated guidelines, the question of PFO closure remains a complex entity.
The findings are relevant for patients with insulin resistance but no history of diabetes.
Incidence of ischemic stroke does not appear to be influenced by exposure to tumor necrosis factor(TNF)-inhibitor use in patients with rheumatoid arthritis.
Risk of VTE was only observed in patients with migraine with aura, suggesting a mechanistic link between the 2 conditions.
Still, regional variations exist, indicating that more personalized prevention programs may be needed.
Overall, men had smoked longer, more daily, and their total exposure in pack-years was greater than women.
Time, however, still plays a big role in stroke outcomes.
Treating older patients with a vitamin K antagonist may be warranted since thrombosis risk is more markedly increased than bleeding risk with rising age.
Within one year of the MI event, patients were at an elevated risk of all stroke subtypes.
Very limited data are available addressing the effect of CYP2C19 variants on clopidogrel efficacy in stroke, especially in Asian populations.
It's important that these strategies be vetted much the same as other medical interventions.
Microbleeds were prevalent in 15.3% of the cohort.
The study analyzed the hospital records of over 1500 patients.
Risk factors differ for early vs late-onset dementia after ICH.
A joint medical and surgical approach may ensure the best outcome.
Multivariable analysis revealed that the odds of a fatal stroke increased by 61% with each decade the patients aged.
AAN GDDI subcommittee seemed less than supportive of the use of etanercept in post-stroke disability.
Neurology Advisor Articles
- No Evidence of Disease Activity Achieved in Multiple Sclerosis with Dimethyl Fumarate
- New Guideline Tackles Sudden Unexpected Death in Epilepsy
- AAN 2017: What To Expect at This Year's American Academy of Neurology Annual Meeting
- Increased Rates of Narcolepsy, Hypersomnia Linked to H1N1 Vaccine
- Adjunct Medical Food Holds Benefits for Parkinson's Disease
- New Guideline Tackles Sudden Unexpected Death in Epilepsy
- History of Migraine Yields Higher Risk for Hypertension in Women
- Alzheimer's Related Gene May Induce Psychosis in Females
- Biomarker Identified for Cerebral Small Vessel Disease Burden, Progression
- Pediatric Multiple Sclerosis Linked to Epstein-Barr, Herpes Simplex Virus Exposure