Stroke News Archive

No Benefit for IV tPA Before Mechanical Thrombectomy in Ischemic Stroke

No Benefit for IV tPA Before Mechanical Thrombectomy in Ischemic Stroke

Intravenous thrombolysis prior to mechanical thrombectomy did not benefit patients with acute ischemic stroke due to a large vessel occlusion.

Continued Warfarin Therapy Helps Prevent Stroke After Dementia Dx

Continued Warfarin Therapy Helps Prevent Stroke After Dementia Dx

Warfarin protected against ischemic stroke, major bleeding, and all-cause mortality in patients who continued to take the drug after dementia diagnosis.

Oral Bacteria May Cause Cerebral Microbleeds, Stroke

Oral Bacteria May Cause Cerebral Microbleeds, Stroke

Streptococcus mutans may raise the risk of cerebral microbleeds and stroke.

SSRI Use Tied to Risk of Intracranial Hemorrhage

SSRI Use Tied to Risk of Intracranial Hemorrhage

Concomitant use of oral anticoagulants contributed to a significantly higher increased risk for ICH.

Increased Stroke Risk Following Percutaneous Coronary Intervention

Increased Stroke Risk Following Percutaneous Coronary Intervention

Risk of stroke is greatest in the first 2 days after the intervention, then gradually decreases.

Catheter Ablation of Atrial Fibrillation Associated With Strokes in Elderly

Catheter Ablation of Atrial Fibrillation Associated With Strokes in Elderly

At 1 year, no difference in complications was observed between the 2 age groups.

Stroke Recurrence Risk Low After Atrial Fibrillation Ablation

Stroke Recurrence Risk Low After Atrial Fibrillation Ablation

Twelve months after AFib ablation, risk of recurrent stroke or AFib is low.

VIDEO: Identifying Risk Factors for Post-Stroke Epilepsy

VIDEO: Identifying Risk Factors for Post-Stroke Epilepsy

Beate Diehl, MD, PhD, FRCP, discusses her research on post-stroke epilepsy.

A Novel Risk Score for Seizures After Stroke

A Novel Risk Score for Seizures After Stroke

The triple-validated SeLECT score may help identify patients suited for antiepileptic drug trials.

Age, Lesion Volume Influence Epilepsy Risk After Stroke

Age, Lesion Volume Influence Epilepsy Risk After Stroke

Patients with lesions in the left basal ganglia were more likely to have post-stroke epilepsy.

Migraine History May Double Stroke Risk in Women

Migraine History May Double Stroke Risk in Women

Women with a history of migraine headache had a more than 2-fold increased risk of stroke over a 6-year follow-up period.

Pushing the Limits of Endovascular Therapy for Acute Ischemic Stroke

Pushing the Limits of Endovascular Therapy for Acute Ischemic Stroke

Recent research found benefits in outcome outweighed any increase in hemorrhagic complications in patients with large infarcts.

CT Scans May Help Identify Stroke

CT Scans May Help Identify Stroke

CT scans may guide the decision to use thrombolysis in patients with unknown time of stroke onset.

Competing Risks Impact Warfarin's Effect on Thromboembolism Risk

Competing Risks Impact Warfarin's Effect on Thromboembolism Risk

Warfarin-linked reduction in VTEis attenuated after accounting for competing death events.

Many AFib Patients Not Taking Oral Anticoagulants Despite Stroke Risk

Many AFib Patients Not Taking Oral Anticoagulants Despite Stroke Risk

Only 46% of patients with indications received OACs at discharge from the hospital.

Effect of Antihypertensives, Statins on Cognitive Decline Uncertain

Effect of Antihypertensives, Statins on Cognitive Decline Uncertain

The effect of antihypertensive drugs and stains on cognition is uncertain.

Many AFib Patients Unaware of Stroke Risk

Many AFib Patients Unaware of Stroke Risk

32.1% believed that heart attack is a major risk factor of AF, which is incorrect.

Antacids and Risk of First-Time Stroke

Antacids and Risk of First-Time Stroke

Another class of antacids, H2 receptor antagonists, had no impact on stroke risk.

Serious Adverse Events, Cardiovascular Health Impact Stroke Risk in RA

Serious Adverse Events, Cardiovascular Health Impact Stroke Risk in RA

Serious adverse events, especially those requiring hospitalization, may indicate an elevated risk of stroke.

Allopurinol Use May Reduce Risk of Stroke in Elderly

Allopurinol Use May Reduce Risk of Stroke in Elderly

The neuroprotective effect was evident after at least 6 months of use.

Pregnancy Increases Stroke Risk in Younger, But Not Older, Women

Pregnancy Increases Stroke Risk in Younger, But Not Older, Women

Pregnancy is a major risk factor for stroke in younger women, but not in older women.

Antiplatelet Use Linked to Hematoma Growth, Outcomes in Intracerebral Hemorrhage

Antiplatelet Use Linked to Hematoma Growth, Outcomes in Intracerebral Hemorrhage

Notably, the location of ICH influenced the association with hematoma volume and growth in patients with prior antiplatelet use.

FDA Approves Patent Foramen Ovale Occluder for Prevention of Recurrent Stroke

FDA Approves Patent Foramen Ovale Occluder for Prevention of Recurrent Stroke

Careful evaluation is required to rule out any other known causes of stroke in patients with PFO.

Factors Associated With Hydrocephalus After Pediatric Intraventricular Hemorrhage

Factors Associated With Hydrocephalus After Pediatric Intraventricular Hemorrhage

Risks associated with certain NSAIDS and steroids warrant further investigation.

MRI More Sensitive, Specific Than Ultrasound in Diagnosing Fetal Stroke

MRI More Sensitive, Specific Than Ultrasound in Diagnosing Fetal Stroke

Out of 34 cases of MRI-detected fetal stroke, ultrasound was only able to identify 5 cases.

Short Episodes of Tachycardia, AFib Have Little to No Effect on Stroke Risk

Short Episodes of Tachycardia, AFib Have Little to No Effect on Stroke Risk

Long episodes of AT/AF were more likely to be associated with clinical events than short episodes.

Elevated Cardiac Troponin T Levels May Be Associated With Cerebral Microbleeds

Elevated Cardiac Troponin T Levels May Be Associated With Cerebral Microbleeds

In the future, hs-cTnT may be a possible risk marker upfront of treatment decisions, especially in patients combined with detected CMBs.

Embolic Protection Improves Neurological Outcomes During TAVR

Embolic Protection Improves Neurological Outcomes During TAVR

The study was underpowered to detect differences in all-cause mortality and stroke.

Sleep Apnea Boosts Risk of Atrial Fibrillation, Blood Clots Post-Op

Sleep Apnea Boosts Risk of Atrial Fibrillation, Blood Clots Post-Op

Patients with untreated OSA face an increased risk of complications.

Glyburide Promising for Treatment of Acute Ischemic Stroke

Glyburide Promising for Treatment of Acute Ischemic Stroke

Although the study did not demonstrate efficacy of glyburide, differences were seen in the amount midline shift at 3-4 days.

Challenges Remain in Understanding Role of Hypertension in Cognition

Challenges Remain in Understanding Role of Hypertension in Cognition

A committee from the American Heart Association failed to make specific clinical recommendations for the management of hypertension related to cognitive impairment.

Complications That Disrupt Rehabilitation Usually Avoidable

Complications That Disrupt Rehabilitation Usually Avoidable

Preventable causes include dehydration, heart failure, pneumonia, and UTIs.

Early Endovascular Thrombectomy Reduces Ischemic Stroke Disability

Early Endovascular Thrombectomy Reduces Ischemic Stroke Disability

Patients with acute ischemic stroke experienced less disability when treated with early endovascular thrombectomy.

Cerebral Microbleeds and Risk of Intracerebral Hemorrhage After Stroke

Cerebral Microbleeds and Risk of Intracerebral Hemorrhage After Stroke

Cerebral microbleeds increase the risk for symptomatic ICH after thrombolysis for acute ischemic stroke.

Semaglutide Reduces Stroke, Mortality in Patients With Diabetes

Semaglutide Reduces Stroke, Mortality in Patients With Diabetes

At baseline, 83% of the patients had established cardiovascular disease, chronic kidney disease, or both.

Increased Stroke Risk Among Pts With Autoimmune Disease, Herpes Zoster

Increased Stroke Risk Among Pts With Autoimmune Disease, Herpes Zoster

Strategies to decrease risk of contracting varicella zoster virus need to be addressed in populations with autoimmune disease.

Contralaterally Controlled Functional Stimulation Improves Dexterity After Stroke

Contralaterally Controlled Functional Stimulation Improves Dexterity After Stroke

Ninety-seven percent of people who received CCFES reported improved use of their hands.

Weight Linked to Ischemic, But Not Hemorrhagic Stroke in Women

Weight Linked to Ischemic, But Not Hemorrhagic Stroke in Women

Being overweight may slightly lower chances for hemorrhagic stroke, the study found.

Clot Retrieval Devices Given Expanded Marketing Approval

Clot Retrieval Devices Given Expanded Marketing Approval

The Trevo devices are the first to be indicated for use in conjunction with IV tPA.

Hypocalcemia May Worsen Bleeding in Intracerebral Hemorrhage

Hypocalcemia May Worsen Bleeding in Intracerebral Hemorrhage

Lower serum calcium levels correlate with risk of hematoma expansion in intracerebral hemorrhage.

Benefit of CPAP Not Apparent for Cardiovascular Disease

Benefit of CPAP Not Apparent for Cardiovascular Disease

The researchers noted that CPAP users may not be using the device long enough to see benefits for their cardiovascular health.

Does Giant Cell Arteritis Increase Risk of Venous Thromboembolism?

Does Giant Cell Arteritis Increase Risk of Venous Thromboembolism?

Studies have linked GCA with increased risk of VTE; however, results have been compromised by limited data sets.

Late-Onset Asthma Linked to Increased Stroke, CVD Risk

Late-Onset Asthma Linked to Increased Stroke, CVD Risk

Doctors should be monitoring for high blood pressure and cholesterol in this patient population.

Inflammatory Biomarkers May Help Predict, Prevent Stroke

Inflammatory Biomarkers May Help Predict, Prevent Stroke

Four blood biomarkers are associated with an increased risk of ischemic stroke.

Experimental Stem Cell Therapy May Reverse Brain Damage in Stroke

Experimental Stem Cell Therapy May Reverse Brain Damage in Stroke

In mice, the protein triggered the stem cells to become functioning neurons.

Calcium Supplementation May Raise Dementia Risk in Older Women

Calcium Supplementation May Raise Dementia Risk in Older Women

Women who received calcium supplementation were at a greater risk for dementia and dementia with stroke.

Hemoglobin Level Adversely Impacts Stroke Mortality

Hemoglobin Level Adversely Impacts Stroke Mortality

Associations with increased mortality were found for both low and high hemoglobin levels, suggesting a U-shaped relationship.

Physical Function Measures May Help Predict Dementia

Physical Function Measures May Help Predict Dementia

Weaker handgrip was also associated with an elevated risk of stroke.

Filter Device Protects Against Brain Injury in TAVI

Filter Device Protects Against Brain Injury in TAVI

Both lesion count and volume was less in the treatment group vs controls.

Sleep Disorders and Stroke: Impact and Treatment Review

Sleep Disorders and Stroke: Impact and Treatment Review

Several studies have also suggested that sleep-wake disorders may also negatively impact neuroplasticity and stroke recovery.

Guideline Update: Management of Recurrent Stroke With Patent Foramen Ovale

Guideline Update: Management of Recurrent Stroke With Patent Foramen Ovale

Despite 3 large randomized trials and updated guidelines, the question of PFO closure remains a complex entity.

Pioglitazone Reduces Diabetes Risk in Patients With Ischemic Stroke

Pioglitazone Reduces Diabetes Risk in Patients With Ischemic Stroke

The findings are relevant for patients with insulin resistance but no history of diabetes.

Effects of TNF Inhibitors on Incidence of Ischemic Stroke in RA

Effects of TNF Inhibitors on Incidence of Ischemic Stroke in RA

Incidence of ischemic stroke does not appear to be influenced by exposure to tumor necrosis factor(TNF)-inhibitor use in patients with rheumatoid arthritis.

Migraine, Venous Thromboembolism May Share Mechanistic Link

Migraine, Venous Thromboembolism May Share Mechanistic Link

Risk of VTE was only observed in patients with migraine with aura, suggesting a mechanistic link between the 2 conditions.

90% of Stroke Worldwide Attributable to 10 Modifiable Risk Factors

90% of Stroke Worldwide Attributable to 10 Modifiable Risk Factors

Still, regional variations exist, indicating that more personalized prevention programs may be needed.

Smoking Linked to Dose-Dependent Risk for Subarachnoid Hemorrhage

Smoking Linked to Dose-Dependent Risk for Subarachnoid Hemorrhage

Overall, men had smoked longer, more daily, and their total exposure in pack-years was greater than women.

Primary Stroke Centers Provide Survival Benefit for Acute Stroke

Primary Stroke Centers Provide Survival Benefit for Acute Stroke

Time, however, still plays a big role in stroke outcomes.

Benefit of Vitamin K Antagonist Outweighs Bleeding Risk in Elderly

Benefit of Vitamin K Antagonist Outweighs Bleeding Risk in Elderly

Treating older patients with a vitamin K antagonist may be warranted since thrombosis risk is more markedly increased than bleeding risk with rising age.

Long-Term Risk of Ischemic Stroke After Myocardial Infarction

Long-Term Risk of Ischemic Stroke After Myocardial Infarction

Within one year of the MI event, patients were at an elevated risk of all stroke subtypes.

Clopidogrel May Not Reduce Stroke Risk in Carriers of Certain CYP2C19 Alleles

Clopidogrel May Not Reduce Stroke Risk in Carriers of Certain CYP2C19 Alleles

Very limited data are available addressing the effect of CYP2C19 variants on clopidogrel efficacy in stroke, especially in Asian populations.

Digital Technology and Improving Cardiovascular Care, Outcomes

Digital Technology and Improving Cardiovascular Care, Outcomes

It's important that these strategies be vetted much the same as other medical interventions.

Microbleed Volume Influences Risk of Cognitive Decline, Dementia

Microbleed Volume Influences Risk of Cognitive Decline, Dementia

Microbleeds were prevalent in 15.3% of the cohort.

Statins May Lower Infection Risk Post-Stroke

Statins May Lower Infection Risk Post-Stroke

The study analyzed the hospital records of over 1500 patients.

Risk Factors for Dementia Vary After Intracerebral Hemorrhage

Risk Factors for Dementia Vary After Intracerebral Hemorrhage

Risk factors differ for early vs late-onset dementia after ICH.

Blood Pressure Management Is Only Part of the Story in Intracerebral Hemorrhage

Blood Pressure Management Is Only Part of the Story in Intracerebral Hemorrhage

A joint medical and surgical approach may ensure the best outcome.

Prevention is Key to Solving Stroke Mortality Race Disparity

Prevention is Key to Solving Stroke Mortality Race Disparity

Multivariable analysis revealed that the odds of a fatal stroke increased by 61% with each decade the patients aged.

AAN Issues Practice Advisory for Etanercept in Post-Stroke Disability

AAN Issues Practice Advisory for Etanercept in Post-Stroke Disability

AAN GDDI subcommittee seemed less than supportive of the use of etanercept in post-stroke disability.

Should Stroke Patients of Asian Descent Get Less tPA?

Should Stroke Patients of Asian Descent Get Less tPA?

The idea of low-dose tPA will likely not be abandoned despite recent findings.

Hyperglycemia, Infarct Size Impact Outcomes in Pediatric Stroke

Hyperglycemia, Infarct Size Impact Outcomes in Pediatric Stroke

Abnormal vital signs in these patients may be more common than previously thought.

Fast Reperfusion Leads to Improved Outcomes in Stroke

Fast Reperfusion Leads to Improved Outcomes in Stroke

Patients who initially arrived at a referring facility had longer symptom onset to groin puncture times.

No Difference Between Bivalirudin, Heparin for Cerebral Embolization in TAVR

No Difference Between Bivalirudin, Heparin for Cerebral Embolization in TAVR

The researchers observed no significant difference between the groups in the proportion of patients with 1 or more new cerebral embolus on MRI.

Aspirin May Prevent Stroke After Transient Ischemic Attack

Aspirin May Prevent Stroke After Transient Ischemic Attack

The risk of stroke was reduced by as much as 80%.

More Evidence for Aggressive Treatment of Hypertension in Elderly

More Evidence for Aggressive Treatment of Hypertension in Elderly

Patients on tighter blood pressure control faced a slightly higher risk of dizzy spells and syncope.

More Choices of Antiplatelet Agents for the Secondary Prevention of Stroke

More Choices of Antiplatelet Agents for the Secondary Prevention of Stroke

Ticagrelor may have an opportunity to shine in patients already on aspirin or clopidogrel.

Low-Dose Alteplase Not Noninferior to Standard Dose in Ischemic Stroke

Low-Dose Alteplase Not Noninferior to Standard Dose in Ischemic Stroke

Low dose alteplase was not noninferior to standard dose for the primary outcome of death and disability at 90 days.

Ticagrelor vs Aspirin in Ischemic Stroke, Transient Ischemic Attack

Ticagrelor vs Aspirin in Ischemic Stroke, Transient Ischemic Attack

In the SOCRATES trial, patients were randomly assigned to ticagrelor or aspirin for 90 days.

Blood Pressure Patterns Indicate Stroke, Mortality Risk

Blood Pressure Patterns Indicate Stroke, Mortality Risk

Those whose blood pressure rose steeply in middle age had the highest risk of stroke.

Selective Serotonin Reuptake Inhibitor Use in Diabetes Increases Stroke Mortality

Selective Serotonin Reuptake Inhibitor Use in Diabetes Increases Stroke Mortality

Selective serotonin reuptake inhibitor use increases risk for patients hospitalized with stroke.

New Guidelines for Adult Stroke Rehabilitation and Recovery

New Guidelines for Adult Stroke Rehabilitation and Recovery

Communication and coordination among the healthcare team are essential for a stroke patient's survival.

Depression, Anxiety Affect Functional Outcome After Stroke, TIA

Depression, Anxiety Affect Functional Outcome After Stroke, TIA

The psychological consequences of stroke appear to influence outcomes.

In Acute Stroke, Stent Retrievers Improve Functional Outcome

In Acute Stroke, Stent Retrievers Improve Functional Outcome

Fast reperfusion leads to improved functional outcome in cases where stent retrievers are used.

Personal Health Records Encourage Engagement, Improve Readmission Rates in Stroke

Personal Health Records Encourage Engagement, Improve Readmission Rates in Stroke

Personal health records have the potential to empower patients as they transition from hospital to home.

Botox May Be Effective Treatment for Lower Limb Spasticity After Stroke

Botox May Be Effective Treatment for Lower Limb Spasticity After Stroke

While Botox is approved by the US FDA for the treatment of poststroke upper limb spasticity, its efficacy in poststroke lower limb spasticity is still being investigated.

Nurse-Activated Stroke Codes Improve Process, Clinical Outcomes

Nurse-Activated Stroke Codes Improve Process, Clinical Outcomes

A nurse-driven stroke evaluation algorithm improved patient triage and treatment utilization.

Recommended Reversal Time of Vitamin K Antagonists Identified for ICH

Recommended Reversal Time of Vitamin K Antagonists Identified for ICH

As ICH volume is known to increase within the first 3 hours following intracerebral hemorrhage, timely reversal is vital for patients on anticoagulation.

Aspirin Use Prior to Stroke May Reduce Stroke Severity

Aspirin Use Prior to Stroke May Reduce Stroke Severity

Research indicates a neuroprotective relationship for aspirin use in stroke.

Insertable Cardiac Monitors Detected AF in Real-World Patients With Cryptogenic Stroke

Insertable Cardiac Monitors Detected AF in Real-World Patients With Cryptogenic Stroke

The incidence of atrial fibrillation in stroke patients with an insertable cardiac monitor was higher than that reported previously.

Statins After Ischemic Stroke Not Linked To Hemorrhagic Complications

Statins After Ischemic Stroke Not Linked To Hemorrhagic Complications

Statins early after stroke may be associated with lower mortality.

Daily Fresh Fruit Intake May Help Reduce Stroke Risk

Daily Fresh Fruit Intake May Help Reduce Stroke Risk

Those who ate a half cup of fruit per day had reduced risk of cardiovascular diseases.

Botox May Relieve Pain in Post-Stroke Spasticity

Botox May Relieve Pain in Post-Stroke Spasticity

The results are promising, but need to be confirmed.

Intraarterial Chemo-Radiation Increases Risk of Cerebral Infarctions

Intraarterial Chemo-Radiation Increases Risk of Cerebral Infarctions

The risk was compared to intravenous chemoradiotherapy.

Right Brain Integrity Affects Speech Fluency After Stroke

Right Brain Integrity Affects Speech Fluency After Stroke

The researchers said this may indicate a premorbid anatomical variability that proves to be beneficial in recovery.

Adherence to Statin, Antihypertensive Therapies Cuts Stroke Risk

Adherence to Statin, Antihypertensive Therapies Cuts Stroke Risk

Adherence to at least one of the treatments reduced risk of fatal stroke.

Acute Cocaine Use Tied to Elevated Stroke Risk

Acute Cocaine Use Tied to Elevated Stroke Risk

More than 50% of participants who used within 24 hours used within 6 hours of their event.

Morning Home Blood Pressure Reading Good Predictor of Stroke, CAD

Morning Home Blood Pressure Reading Good Predictor of Stroke, CAD

The prediction of events was more robust with home readings compared with clinic readings.

Anticoagulant Treatment Falling Short in AFib Patients

Anticoagulant Treatment Falling Short in AFib Patients

The authors suggest that physicians may be concerned about bleeding risk.

Obesity, Oral Contraceptives Increase Risk of Cerebral Venous Thrombosis

Obesity, Oral Contraceptives Increase Risk of Cerebral Venous Thrombosis

Women who were obese and taking oral contraceptives had a 29-fold increased risk of CVT.

Longer Sleep Duration Linked to Intracerebral Hemorrhage Risk

Longer Sleep Duration Linked to Intracerebral Hemorrhage Risk

Sleep duration has previously been linked to hypertension and stroke risk.

Recurrence Risk Estimator Score for Ischemic Stroke Validated

Recurrence Risk Estimator Score for Ischemic Stroke Validated

The score can identify patients at high and low risk of recurrence for stroke.

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