Stroke News Archive
All patients included in the study underwent a MRI or multimodal CT approximately 24 hours after onset of stroke.
Ischemic and hemorrhagic strokes are a common complication of infective endocarditis, but guidance on intervention is varied.
Long-term, high-dose usage of PPIs increases the risk of first-time ischemic stroke and myocardial infarction.
Direct oral anticoagulant use is not linked with an increase in major bleeding in patients with VTE.
The American Heart and American Stroke Associations have developed an outline focused on the impact of cognitive impairment on public health, and the maintenance and definition of optimal brain health.
While the increase in cardiovascular risk factors is at least partially due to the obesity epidemic, the researchers believe the increase is multifactorial.
Results from a secondary analysis of the ENCHANTED trial add to a pile of weak data that likely will not affect clinical practice.
The trial, sponsored by the University of Birmingham, is currently recruiting participants.
Significant infarct progression can make patients ineligible for mechanical thrombectomy.
Risk scores help identify high-risk patients who may benefit from intervention.
Mechanisms including silent cerebral infarct, microemboli, microbleedings, and cerebral hypoperfusion may be responsible for the link between atrial fibrillation and cognitive decline.
The findings support the continuation of high-intensity statin therapy after acute ischemic stroke.
Insulin-resistant patients with ischemic stroke or transient ischemic attack and a high risk of myocardial infarction or recurrent stroke are more likely to derive benefit from pioglitazone than those a lower risk.
There is a reduced risk of adverse events associated with genotype-guided warfarin dosing.
For long-term low-dose aspirin users, there is a 30% increased risk of CVD events with discontinuation of aspirin.
Low-dose oxygen use does not reduce death or disability at 3 months among patients with acute stroke.
A better understanding of characteristics of cerebral lesions may help expedite treatment and improve functional outcomes.
Newer antiepileptic drugs were associated with fewer adverse effects in patients with ischemic stroke.
The investigators noted that rivaroxaban was associated with significantly reduced length of hospital stay compared with warfarin.
The findings align with current guidelines to administer IV tPA regardless of whether or not a patient with ischemic stroke is set to undergo mechanical thrombectomy.
Early supported discharge services may also help care facilities better manage their need for hospital beds and conventional hospital stay costs.
Participants with high baseline levels of SCF had lower all-cause mortality and reduced risk of heart failure, stroke, and myocardial infarction.
There is some evidence that suggests intravenous thrombolysis for stroke may impair the blood-brain barrier and cause cerebral edema.
Brief periods of oxygen deprivation to the brain have been shown to provide neuroprotective effects that reduce stroke infarct size and improve recovery times.
Surprisingly, no evidence was found to suggest that patients with these markers benefit from intensive blood pressure reduction.
The findings may be less applicable to low-volume stroke centers who have less experience in this treatment.
Younger adults who use methamphetamine are at a greater risk for stroke.
The 30-day cumulative incidences of stroke were 2.16% and 0.21% for patients with hip fracture and the general population.
About 1 in 20 patients with VTE have occult cancer detected within a year.
There is no increased risk for stroke for people with thyroid cancer who receive radioiodine therapy.
Investigators found a positive association between higher childhood BMI scores and early adult ischemic stroke.
Hepatitis C virus (HCV) infection may also increase the risk of stroke.
The incidence of intracerebral hemorrhage and subarachnoid hemorrhage was stable in both men and women.
THRIVE scores not only accurately predicted good and poor outcomes in stroke patients following IVT or ET, but also the degree of ischemia following these treatments.
Despite disappointing results, tenecteplase's story in stroke treatment might not be over.
Women and patients of African-American race face an increased risk of experiencing poststroke recrudescence.
There is an increased risk of a recurrent stroke after discontinuing statin therapy 3 to 6 months post initial ischemic stroke.
Only 16% of patients had an adequate response to conventional therapy, with patients who didn't considered "non-responders."
Less than half of individuals with ischemic stroke receive a prescription for statins.
Birthplace is a significant risk factor for dementia, even after adjusting for educational levels, race, and life-course vascular risk factors.
Subarachnoid hemorrhage must be ruled out in patients with acute onset of severe headache.
There are a limited number of prediction models that identify patients at risk of major bleeding after stroke or TIA.
The update focused on diagnosis of neuropathic pain in patients with spinal cord injury, stroke, or multiple sclerosis.
At 90-days, the rate of thrombotic events in both groups was low.
The Penumbra 3D revascularization device was recalled by the FDA because of a risk of the delivery wire breaking during use.
Rivaroxaban treatment for nonvalvular AF in patients with cancer is safe.
The risk of a second stroke or transient ischemic attack (TIA) remains considerable for at least 5 years after the first event.
Although spot sign predicted ICH expansion, it proved to be a less robust diagnostic marker than demonstrated by previous single-center cohort studies.
An increase in BMI during puberty and adolescence was associated with increase risk of stroke.
Reduced door-to-needle times have been shown to improve outcomes after stroke.
Patients with cirrhosis had a 2.17% per year incidence of stroke compared with 1.11% per year incidence of stroke in patients without cirrhosis.
Music-and-rhythm therapy has also been shown to help improve balance and memory.
Clinicians should make patients aware of their increased risk for stroke and heart attack.
Risk for symptomatic intracranial hemorrhage after endovascular treatment for acute ischemic stroke is significantly higher in real-world practice than rates reported by clinical trials.
Positioning of the head in acute ischemic stroke does not seem to affect recovery.
According to a study published in Stroke artificially-sweetened beverages is associated with increased risk of stroke and dementia.
Compared with other sources of ICH, those associated with arteriovenous malformations had lower odds of death.
Intracranial atherosclerosis was lower in patients with migraine compared with those without migraine.
Dual therapy was associated with a significantly higher bleeding risk.
Delays in anticoagulation treatment resulted in increased risk for dementia.
No between-group differences were observed for reperfusion success and mortality, among other measures.
Neglecting abnormalities in ECG readings could result in serious acute cardiac events in patients presenting with stroke.
Intensive antiplatelet therapy appears to reduce risk of recurrence immediately after stroke, but may pose risks further out.
New research from the American Heart and American Stroke Associations found that many Americans don't know the symptoms of stroke.
Findings from a new study suggest that engaging in stroke prevention strategies may help reduce the risk of dementia.
Men who received testosterone replacement therapy had lower odds of cardiovascular events.
Monitored anesthesia was found to be as safe and effective as general anesthesia in patients undergoing endovascular therapy for stroke.
E-health-based coagulation service was linked to lower frequency of adverse events, including thromboembolism, bleeding, and death.
The relative risk of developing ischemic stroke was increased in patients with systemic lupus erythematosus, especially within the first year after diagnosis.
Neurologists need to engage their emergency medicine colleagues to identify protocols and pathways for when to trigger appropriate neurological consultation or initiate acute stroke therapies.
During the study period, the percentage of people with 3 or more stroke risk factors roughly doubled for all age groups.
Previous studies have produced contradictory evidence of a link between serum UA and stroke risk, with some pointing to greater risks in women compared with men.
Over 32% of patients were functionally independent at 90 days and 37.1% were functionally independent at 2 years.
There is little data to support telestroke for IV thrombolysis administration in the extended time window of 3 to 4.5 hours after stroke onset.
Pulse pressure was associated with the risk for ischemic stroke in first-ever ischemic stroke patients old than 60 years.
Resumption of oral anticoagulants after intracerebral hemorrhage was found to improve outcomes at 1 year.
Mortality among women with preeclampsia and pregnancy-associated stroke was significantly higher than in controls.
Previous research had suggested that the benefits of IV tPA are diminished in patients weighing more than 100 kg.
Higher glucose levels reduce likelihood of good outcome among stroke patients with good collaterals.
Having sickle cell disease did not adversely affect any of the indicators the researchers measured.
Patients taking apixaban showed significantly less intracranial hemorrhage (0.33% per year) vs patients taking warfarin (0.80% per year), no matter the type and location.
Patients who exercised prior to their stroke were more likely to be able to perform basic and complex tasks after the stroke event.
The investigators reported no difference in 3-month mortality rates across all 5 studies included in the meta-analysis.
Use of mobile stroke units is associated with reduced time to imaging and thrombolysis compared with traditional care.
There is no urgency to administer preexisting antihypertensive therapy in the first few hours or days after stroke, unless indicated for other comorbid conditions.
A substantial number of strokes may be due to underuse of or inadequate anticoagulation in Afib.
Admission hyperglycemia was associated with poststroke infection, as well as 3-month functional outcome and mortality.
Results at 3 years for tenecteplase vs placebo in patients with intermediate-risk pulmonary embolism.
Recurrent fatal or nonfatal VTE occurred in 1.5% of patients who took 20 mg of rivaroxaban, 1.2% of patients who took 10 mg, and 4.4% who took aspirin.
Patients with inherited thrombophilias who did not undergo patent foramen ovale closure faced a significantly increased risk of stroke.
More than 80% of ischemic stroke patients weren't getting adequate anticoagulation therapy.
Up to 20% of stroke cases in young adults occur in those with cervical artery dissection, the leading cause of stroke in this population.
Clinicians should closely monitor patients with atrial fibrillation, especially if they are female and of increasing age.
Efficacy of triple antiplatelet therapy compared with current guideline-based therapy for the prevention of recurrent stroke was evaluated in the TARDIS trial.
The increase in usage of antithrombotics, especially vitamin K antagonists, has been linked to an increase in prevalence of subdural hematomas.
More patients receiving VNS experienced enhanced arm movement over a 90-day period.
Restarting anticoagulation after both nonlobar and lobar ICH was associated with decreased mortality.
Men were more likely than women to be treated with IV tPA within 30 minutes of arrival at a hospital.
As more patients survive ICH, emphasis is slowly shifting from survival to improving ICH-related morbidity and optimization of functional recovery.
The results provide good evidence for the use of contact aspiration in ischemic stroke.
Neurology Advisor Articles
- Coffee Consumption May Decrease Stroke Risk
- Prochlorperazine More Effective Than Ketamine for Headache Relief in the Emergency Department
- CTE Confirmed With Antemortem PET Imaging, Autopsy in Professional Football Player
- Intranasal Sumatriptan More Effectively Reduces Migraine-Associated Nausea
- Neuropsychiatric Conditions Common in Relatives of Patients With Amyotrophic Lateral Sclerosis
- Treating Cluster Headache: Weighing Current Therapies
- Alzheimer Disease Linked to High Cumulative Doses of Zolpidem in Elderly
- NBT System Gets FDA Clearance for Depression Treatment
- Better Migraine Pain Relief With IV Non-Opioid Combination vs IV Hydromorphone
- FDA Approves Myasthenia Gravis Treatment
- Reports of Agranulocytosis Prompt Monitoring for Investigational Parkinson's Drug
- Nusinersen Improves Motor Function, Survival in Infants With Spinal Muscular Atrophy
- Noninvasive Brain Stimulation System Approved for Depression
- Hypertension Guidelines Updated by AHA/ACA
- Bone Mineral Density Associated With Intracranial Aneurysm Presence, Size