Stroke News Archive
Although several studies have established the use of endovascular therapy with stent retrievers for selected acute stroke as standard of care, best practices surrounding the best sedation strategy remain unclear.
There is a significant increased risk of coronary heart disease and stroke linked with smoking just 1 cigarette per day.
Many stroke patients referred to rehabilitation services, do not actually receive these services.
Although renal cysts are generally thought of as benign findings, this study points to a possible higher stroke risk in patients with multiple cysts.
Percutaneous patent foramen ovale closure is superior to medical treatment alone in preventing recurrent stroke
Patent foramen ovale closure was superior to medical treatment alone in preventing transient ischemic attack and recurrent stroke.
Thrombectomy performed between 6 and 24 hours after onset of acute stroke in patients with a mismatch between stroke symptoms and infarct volume results in better disability outcomes compared to standard care alone.
The findings suggest that future studies should explore the specific time window in which SSRIs are beneficial.
Under the new ischemic stroke guidelines, the treatment window for thrombectomy has been expanded to up to 24 hours after symptom onset.
Fixed-dose candesartan plus hydrochlorothiazide and rosuvstatin reduced first stroke in patients at intermediate risk for cardiovascular disease.
In this population-based study, researchers found that Mexican Americans had a greater risk for recurrent stroke and death than non-Hispanic whites.
Researchers have observed an upward trend in the incidence of pregnancy-related spontaneous subarachnoid hemorrhage.
A significantly shorter door-to-needle time is associated with the presence of a pharmacist at bedside during acute ischemic stroke.
Screening for coexisting diseases may help identify high-risk patients with intracranial atherosclerotic disease.
CHA2DS2-VASc score assessment is more predictive of ischemic stroke in patients with atrial fibrillation than the baseline score.
In adults with PFO, percutaneous and transcatheter PFO closure prevent recurrent stroke.
Patients who received adjunctive electrostimulation and task-oriented training had greater improvement than patients who received standard rehabilitation.
Clopidogrel tablets were recalled by International Laboratories due to bottle mislabeling.
Outcome measure scores strongly predict discharge destination after acute, subacute stroke
Higher-quality randomized controlled trials are needed in order to better assess the benefits of PPAR-γ agonists in recurrent stroke risk.
There was a significant increase in carotid artery stenting from the pre- to post-CREST period.
Greater yearly declines in systolic and diastolic blood pressure were noted in individuals with subcortical microinfarcts.
Day-to-day BPV was not as strongly associated with risk for stroke, but was comparably associated with the risk for cardiovascular events.
Ginkgo biloba extract along with aspirin alleviates cognitive deficits in acute ischemic stroke.
Hormone therapy for up to 5 years following onset of menopause was found to be associated with a decreased risk for ischemic and hemorrhagic stroke.
Although there was little difference in efficacy, apixaban did have a better safety profile than warfarin, dabigatran, and rivaroxaban.
Women with migraine should avoid high-risk products such as combined oral HCs consisting of >35μg ethinylestradiol.
Updated antithrombotic therapy recommendations for patients with atrial fibrillation have been provided.
Investigators sought to assess the risk of ischemic stroke after a traumatic injury in patients <50 years of age.
The ACC released a new concensus on guiding clinicians in managing acute bleeding for patients treated with OACs.
Older age and premature atrial contractions were independent predictors for stroke risk in patients who had CHA2DS2-VASc scores of 0 or 1.
A systematic review aimed to validate whether stroke risk is increased in women taking estrogen-containing contraceptives who have a history of migraine.
Depression is one of the most commonly reported complications resulting from stroke.
The investigators halted the trial prematurely due to slow recruitment and a lack of treatment efficacy in overall cerebral perfusions.
The FDA has approved evolocumab in adults with CVD for the prevention of heart attacks, strokes, and coronary revascularizations.
A double-blind study evaluated whether repeated single abobotulinumtoxinA injections administered over a year reduces spastic muscle tone in patients with chronic hemiparesis.
Ablation is associated with reduced risk of recurrent stroke for patients with artrial fibrillation.
After stroke, virtual reality training may be as effective for upper extremity rehabilitation as standard care.
The effects of ischemic stroke on disability trajectories over an extended period of time were examined.
The new guidelines for the diagnostic threshold for stage 1 hypertension were lowered from 140/90 to 130/80.
Patients with the lowest bone mineral density had the largest aneurysm size.
In older adults, lower cardiac index is linked to lower cerebral blood blow in the temporal lobe.
Thrombectomy plus standard care is better for patients with acute stroke.
In addition to known risk factors such as blood pressure, age, and cholesterol, coffee and red meat intake were important predictors of heart failure and stroke.
Patients at risk of stroke may benefit from the total homocysteine-lowering effects of folic acid supplementation.
The findings highlight the importance of considering dietary intake as a whole, rather than examining micronutrients on an individual basis.
Patients enrolled in this study had strokes that were mild in severity, reducing the generalizability of these findings to the broader population.
There is a higher prevalence of multiple intracranial atherosclerotic plaques in black men.
Patients who experience acute coronary syndrome are at greater risk of recurrent ischemic events, including stroke.
All patients included in the study underwent a MRI or multimodal CT approximately 24 hours after onset of stroke.
Ischemic and hemorrhagic strokes are a common complication of infective endocarditis, but guidance on intervention is varied.
Long-term, high-dose usage of PPIs increases the risk of first-time ischemic stroke and myocardial infarction.
Direct oral anticoagulant use is not linked with an increase in major bleeding in patients with VTE.
The American Heart and American Stroke Associations have developed an outline focused on the impact of cognitive impairment on public health, and the maintenance and definition of optimal brain health.
While the increase in cardiovascular risk factors is at least partially due to the obesity epidemic, the researchers believe the increase is multifactorial.
Results from a secondary analysis of the ENCHANTED trial add to a pile of weak data that likely will not affect clinical practice.
The trial, sponsored by the University of Birmingham, is currently recruiting participants.
Significant infarct progression can make patients ineligible for mechanical thrombectomy.
Risk scores help identify high-risk patients who may benefit from intervention.
Mechanisms including silent cerebral infarct, microemboli, microbleedings, and cerebral hypoperfusion may be responsible for the link between atrial fibrillation and cognitive decline.
The findings support the continuation of high-intensity statin therapy after acute ischemic stroke.
Insulin-resistant patients with ischemic stroke or transient ischemic attack and a high risk of myocardial infarction or recurrent stroke are more likely to derive benefit from pioglitazone than those a lower risk.
There is a reduced risk of adverse events associated with genotype-guided warfarin dosing.
For long-term low-dose aspirin users, there is a 30% increased risk of CVD events with discontinuation of aspirin.
Low-dose oxygen use does not reduce death or disability at 3 months among patients with acute stroke.
A better understanding of characteristics of cerebral lesions may help expedite treatment and improve functional outcomes.
Newer antiepileptic drugs were associated with fewer adverse effects in patients with ischemic stroke.
The investigators noted that rivaroxaban was associated with significantly reduced length of hospital stay compared with warfarin.
The findings align with current guidelines to administer IV tPA regardless of whether or not a patient with ischemic stroke is set to undergo mechanical thrombectomy.
Early supported discharge services may also help care facilities better manage their need for hospital beds and conventional hospital stay costs.
Participants with high baseline levels of SCF had lower all-cause mortality and reduced risk of heart failure, stroke, and myocardial infarction.
There is some evidence that suggests intravenous thrombolysis for stroke may impair the blood-brain barrier and cause cerebral edema.
Brief periods of oxygen deprivation to the brain have been shown to provide neuroprotective effects that reduce stroke infarct size and improve recovery times.
Surprisingly, no evidence was found to suggest that patients with these markers benefit from intensive blood pressure reduction.
The findings may be less applicable to low-volume stroke centers who have less experience in this treatment.
Younger adults who use methamphetamine are at a greater risk for stroke.
The 30-day cumulative incidences of stroke were 2.16% and 0.21% for patients with hip fracture and the general population.
About 1 in 20 patients with VTE have occult cancer detected within a year.
There is no increased risk for stroke for people with thyroid cancer who receive radioiodine therapy.
Investigators found a positive association between higher childhood BMI scores and early adult ischemic stroke.
Hepatitis C virus (HCV) infection may also increase the risk of stroke.
The incidence of intracerebral hemorrhage and subarachnoid hemorrhage was stable in both men and women.
THRIVE scores not only accurately predicted good and poor outcomes in stroke patients following IVT or ET, but also the degree of ischemia following these treatments.
Despite disappointing results, tenecteplase's story in stroke treatment might not be over.
Women and patients of African-American race face an increased risk of experiencing poststroke recrudescence.
There is an increased risk of a recurrent stroke after discontinuing statin therapy 3 to 6 months post initial ischemic stroke.
Only 16% of patients had an adequate response to conventional therapy, with patients who didn't considered "non-responders."
Less than half of individuals with ischemic stroke receive a prescription for statins.
Birthplace is a significant risk factor for dementia, even after adjusting for educational levels, race, and life-course vascular risk factors.
Subarachnoid hemorrhage must be ruled out in patients with acute onset of severe headache.
There are a limited number of prediction models that identify patients at risk of major bleeding after stroke or TIA.
The update focused on diagnosis of neuropathic pain in patients with spinal cord injury, stroke, or multiple sclerosis.
At 90-days, the rate of thrombotic events in both groups was low.
The Penumbra 3D revascularization device was recalled by the FDA because of a risk of the delivery wire breaking during use.
Rivaroxaban treatment for nonvalvular AF in patients with cancer is safe.
The risk of a second stroke or transient ischemic attack (TIA) remains considerable for at least 5 years after the first event.
Although spot sign predicted ICH expansion, it proved to be a less robust diagnostic marker than demonstrated by previous single-center cohort studies.
An increase in BMI during puberty and adolescence was associated with increase risk of stroke.
Reduced door-to-needle times have been shown to improve outcomes after stroke.
Patients with cirrhosis had a 2.17% per year incidence of stroke compared with 1.11% per year incidence of stroke in patients without cirrhosis.
Music-and-rhythm therapy has also been shown to help improve balance and memory.
Neurology Advisor Articles
- FDA Approves Expanded Treatment Window for Clot Retrieval Device in Acute Ischemic Stroke
- Genetic and Imaging Markers in Migraine: Ready for Prime Time?
- FDA Approves Smart Watch for Epilepsy Management
- Intrathecal Baclofen More Effective Than Oral Antispasmodics for Generalized Poststroke Spasticity
- Alzheimer Disease May Benefit From Deep Brain Stimulation
- Updated Ischemic Stroke Guidelines: Expert Takeaways
- Alternative Genetic Risk Variant for Alzheimer Disease Identified
- Advance Directives for Dementia: Honoring Patient Wishes When You Don't Know What They Are
- Poor Sleep Associated With Worse PTSD, Chronic Pain in Youth
- Intrathecal Baclofen More Effective Than Oral Antispasmodics for Generalized Poststroke Spasticity