Stroke News Archive
During the study period, the percentage of people with 3 or more stroke risk factors roughly doubled for all age groups.
Previous studies have produced contradictory evidence of a link between serum UA and stroke risk, with some pointing to greater risks in women compared with men.
Over 32% of patients were functionally independent at 90 days and 37.1% were functionally independent at 2 years.
There is little data to support telestroke for IV thrombolysis administration in the extended time window of 3 to 4.5 hours after stroke onset.
Pulse pressure was associated with the risk for ischemic stroke in first-ever ischemic stroke patients old than 60 years.
Resumption of oral anticoagulants after intracerebral hemorrhage was found to improve outcomes at 1 year.
Mortality among women with preeclampsia and pregnancy-associated stroke was significantly higher than in controls.
Previous research had suggested that the benefits of IV tPA are diminished in patients weighing more than 100 kg.
Higher glucose levels reduce likelihood of good outcome among stroke patients with good collaterals.
Having sickle cell disease did not adversely affect any of the indicators the researchers measured.
Patients taking apixaban showed significantly less intracranial hemorrhage (0.33% per year) vs patients taking warfarin (0.80% per year), no matter the type and location.
Patients who exercised prior to their stroke were more likely to be able to perform basic and complex tasks after the stroke event.
The investigators reported no difference in 3-month mortality rates across all 5 studies included in the meta-analysis.
Use of mobile stroke units is associated with reduced time to imaging and thrombolysis compared with traditional care.
There is no urgency to administer preexisting antihypertensive therapy in the first few hours or days after stroke, unless indicated for other comorbid conditions.
A substantial number of strokes may be due to underuse of or inadequate anticoagulation in Afib.
Admission hyperglycemia was associated with poststroke infection, as well as 3-month functional outcome and mortality.
Results at 3 years for tenecteplase vs placebo in patients with intermediate-risk pulmonary embolism.
Recurrent fatal or nonfatal VTE occurred in 1.5% of patients who took 20 mg of rivaroxaban, 1.2% of patients who took 10 mg, and 4.4% who took aspirin.
Patients with inherited thrombophilias who did not undergo patent foramen ovale closure faced a significantly increased risk of stroke.
More than 80% of ischemic stroke patients weren't getting adequate anticoagulation therapy.
Up to 20% of stroke cases in young adults occur in those with cervical artery dissection, the leading cause of stroke in this population.
Clinicians should closely monitor patients with atrial fibrillation, especially if they are female and of increasing age.
Efficacy of triple antiplatelet therapy compared with current guideline-based therapy for the prevention of recurrent stroke was evaluated in the TARDIS trial.
The increase in usage of antithrombotics, especially vitamin K antagonists, has been linked to an increase in prevalence of subdural hematomas.
More patients receiving VNS experienced enhanced arm movement over a 90-day period.
Restarting anticoagulation after both nonlobar and lobar ICH was associated with decreased mortality.
Men were more likely than women to be treated with IV tPA within 30 minutes of arrival at a hospital.
As more patients survive ICH, emphasis is slowly shifting from survival to improving ICH-related morbidity and optimization of functional recovery.
The results provide good evidence for the use of contact aspiration in ischemic stroke.
Optimal antiplatelet treatment has yet to be determined for stroke survivors with prior intracerebral hemorrhage.
The co-presentation of headache at stroke onset in children may provide clues to underlying pathophysiologic mechanisms.
Psychological distress may cause changes within cells that trigger inflammation and oxidative stress, both of which are believed to increase stroke risk.
Delays related to the determination of treatment eligibility increased door-to-needle times by more than 30 minutes compared with patients with no delays.
Pulmonary embolism risk was lowest in patients with cerebral venous thromboembolism during the index hospitalization.
Neither lying flat nor sitting up appears to alter outcomes in patients presenting with acute stroke.
Among ICH survivors, 63% developed both depression and dementia during a 5-year follow-up study.
Standardized definitions were proposed for stroke, hypoxic-ischemic injury, and cerebral hemorrhage.
Early intervention in patients with heart failure or atrial fibrillation may help delay or prevent the onset of mild dementia.
Patients receiving treatment with vitamin K antagonists (VKA) or antiplatelet agents face a significantly increased risk of mortality within 24 hours of intracranial hemorrhage.
The difference in rate of recurrence of PCAIS may have to do with a difference in mechanism compared with ACAIS.
Use of advanced imaging may help predict which patients will have an optimal response to treatment with intravenous tissue plasminogen activator.
It is not clear if identifying atrial fibrillation in an effort to prevent stroke would be an effective preventive strategy.
Despite being more common than thought, many cases of neonatal hemorrhagic stroke remain idiopathic.
The use of combined hormonal contraceptives significantly increases the risk of ischemic stroke in women with migraine with aura but not in women with migraine without aura.
Migraine affects approximately 20% of the general population and is associated with an increased risk for ischemic stroke.
The increased risk of stroke was only observed among patients with diabetes controlled by insulin.
Using telestroke to evaluate patients with acute ischemic stroke eligible for thrombolysis provided access to acute stroke care in underserved areas.
A significant inverse trend was observed between the Healthy Nordic Food Index and risk of stroke.
Patients with elevated levels of activity in the amygdala were at higher risk for cardiovascular events.
Intravenous thrombolysis prior to mechanical thrombectomy did not benefit patients with acute ischemic stroke due to a large vessel occlusion.
Warfarin protected against ischemic stroke, major bleeding, and all-cause mortality in patients who continued to take the drug after dementia diagnosis.
Streptococcus mutans may raise the risk of cerebral microbleeds and stroke.
Concomitant use of oral anticoagulants contributed to a significantly higher increased risk for ICH.
Risk of stroke is greatest in the first 2 days after the intervention, then gradually decreases.
At 1 year, no difference in complications was observed between the 2 age groups.
Twelve months after AFib ablation, risk of recurrent stroke or AFib is low.
Beate Diehl, MD, PhD, FRCP, discusses her research on post-stroke epilepsy.
The triple-validated SeLECT score may help identify patients suited for antiepileptic drug trials.
Patients with lesions in the left basal ganglia were more likely to have post-stroke epilepsy.
Women with a history of migraine headache had a more than 2-fold increased risk of stroke over a 6-year follow-up period.
Recent research found benefits in outcome outweighed any increase in hemorrhagic complications in patients with large infarcts.
CT scans may guide the decision to use thrombolysis in patients with unknown time of stroke onset.
Warfarin-linked reduction in VTEis attenuated after accounting for competing death events.
Only 46% of patients with indications received OACs at discharge from the hospital.
The effect of antihypertensive drugs and stains on cognition is uncertain.
32.1% believed that heart attack is a major risk factor of AF, which is incorrect.
Another class of antacids, H2 receptor antagonists, had no impact on stroke risk.
Serious adverse events, especially those requiring hospitalization, may indicate an elevated risk of stroke.
The neuroprotective effect was evident after at least 6 months of use.
Pregnancy is a major risk factor for stroke in younger women, but not in older women.
Notably, the location of ICH influenced the association with hematoma volume and growth in patients with prior antiplatelet use.
Careful evaluation is required to rule out any other known causes of stroke in patients with PFO.
Risks associated with certain NSAIDS and steroids warrant further investigation.
Out of 34 cases of MRI-detected fetal stroke, ultrasound was only able to identify 5 cases.
Long episodes of AT/AF were more likely to be associated with clinical events than short episodes.
In the future, hs-cTnT may be a possible risk marker upfront of treatment decisions, especially in patients combined with detected CMBs.
The study was underpowered to detect differences in all-cause mortality and stroke.
Patients with untreated OSA face an increased risk of complications.
Although the study did not demonstrate efficacy of glyburide, differences were seen in the amount midline shift at 3-4 days.
A committee from the American Heart Association failed to make specific clinical recommendations for the management of hypertension related to cognitive impairment.
Preventable causes include dehydration, heart failure, pneumonia, and UTIs.
Patients with acute ischemic stroke experienced less disability when treated with early endovascular thrombectomy.
Cerebral microbleeds increase the risk for symptomatic ICH after thrombolysis for acute ischemic stroke.
At baseline, 83% of the patients had established cardiovascular disease, chronic kidney disease, or both.
Strategies to decrease risk of contracting varicella zoster virus need to be addressed in populations with autoimmune disease.
Ninety-seven percent of people who received CCFES reported improved use of their hands.
Being overweight may slightly lower chances for hemorrhagic stroke, the study found.
The Trevo devices are the first to be indicated for use in conjunction with IV tPA.
Lower serum calcium levels correlate with risk of hematoma expansion in intracerebral hemorrhage.
The researchers noted that CPAP users may not be using the device long enough to see benefits for their cardiovascular health.
Studies have linked GCA with increased risk of VTE; however, results have been compromised by limited data sets.
Doctors should be monitoring for high blood pressure and cholesterol in this patient population.
Four blood biomarkers are associated with an increased risk of ischemic stroke.
In mice, the protein triggered the stem cells to become functioning neurons.
Women who received calcium supplementation were at a greater risk for dementia and dementia with stroke.
Associations with increased mortality were found for both low and high hemoglobin levels, suggesting a U-shaped relationship.
Weaker handgrip was also associated with an elevated risk of stroke.
Both lesion count and volume was less in the treatment group vs controls.
Several studies have also suggested that sleep-wake disorders may also negatively impact neuroplasticity and stroke recovery.
Neurology Advisor Articles
- Vitamin D Deficiency Affects Cognition in Multiple Sclerosis
- Hypothalamus May Play a Central Role in Chronic Migraine
- An Interdisciplinary Approach to Advanced Parkinson's Care
- Migraine Attacks Associated With Reduced Dopamine Levels
- Polypharmacy in Schizophrenia May Have Adverse Effect on Cognition
- Alzheimer's Mortality Increasing, But So Is At-Home Care
- Special Diets, Supplements for Autism Not Backed by Solid Evidence
- In MS, Disease Duration, Lesion Load Predict Relapses and Disability Progression
- Ocrelizumab May Improve Cognitive Function in Relapsing Multiple Sclerosis
- Teriflunomide for MS Associated With Low Rates of Infection, Lymphopenia