Stroke

Alteplase Good for Ischemic Stroke With Unknown Onset Time

Alteplase Good for Ischemic Stroke With Unknown Onset Time

For patients with ischemic stroke with an unknown time of onset, intravenous alteplase is associated with better functional outcome than placebo.

Prediction Algorithm Stratifies ICH Patients at Risk for Hematoma Expansion

Prediction Algorithm Stratifies ICH Patients at Risk for Hematoma Expansion

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While developing the hematoma expansion prediction score, associations between hematoma expansion and blend sign, any intrahematoma hypodensity, and time from onset to noncontrast computed tomography <2.5 hours were found.

Congenital Heart Disease, Hispanic Ethnicity Associated With Increased Mortality in Pediatric Arterial Ischemic Stroke

Congenital Heart Disease, Hispanic Ethnicity Associated With Increased Mortality in Pediatric Arterial Ischemic Stroke

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The investigators were unable to determine which type of congenital heart disease or which type of ventricular assist device, if used, played a role in mortality outcomes.

Tenecteplase Improves Reperfusion and Functional Outcome in Ischemic Stroke

Tenecteplase Improves Reperfusion and Functional Outcome in Ischemic Stroke

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The findings from this trial are limited to only ischemic stroke patients with large-vessel occlusion who are deemed appropriate for thrombolysis.

Ceftriaxone More Cost-Effective Than Standard Care for Post-Stroke Infection Prevention

Ceftriaxone More Cost-Effective Than Standard Care for Post-Stroke Infection Prevention

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There were no differences between the ceftriaxone and standard care groups in terms of institutional care resources, out-of-pocket expenses, or productivity losses.

Sickle Cell Trait Does Not Reliably Predict Ischemic Stroke in African Americans

Sickle Cell Trait Does Not Reliably Predict Ischemic Stroke in African Americans

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Sickle cell trait is not associated with ischemic stroke and should not be relied upon as a sole predictor of stroke in African Americans.

Poststroke Neurocognitive Disorder Prevalent in Acute Stroke

Poststroke Neurocognitive Disorder Prevalent in Acute Stroke

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A shortened summary cognitive score consisting of action speed, executive function, and language may help diagnose poststroke NCD.

Frequency of Sauna Bathing Linked to Reduced Stroke Risk

Frequency of Sauna Bathing Linked to Reduced Stroke Risk

For adults, frequent sauna bathing is associated with reduced risk of future stroke.

ARISE II Demonstrates Improved Reperfusion With EmboTrap in Ischemic Stroke

ARISE II Demonstrates Improved Reperfusion With EmboTrap in Ischemic Stroke

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The lack of a comparator group as well as the relatively small patient sample represents potential limitations of this study.

Cerebral Microbleeds Do Not Predict 3-Month Death or Disability in Intracerebral Hemorrhage

Cerebral Microbleeds Do Not Predict 3-Month Death or Disability in Intracerebral Hemorrhage

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Investigators performed a pre-planned secondary analysis of the open-label, randomized Antihypertensive Treatment of Acute Cerebral Hemorrhage 2 study, specifically on the magnetic resonance images obtained during the intensive blood pressure lowering portion of the trial.

Previous Stroke Tied to Higher Risks in Aortic Valve Replacement

Previous Stroke Tied to Higher Risks in Aortic Valve Replacement

For patients undergoing surgical aortic valve replacement, previous stroke is a risk factor for recurrent ischemic stroke and major adverse cardiovascular events.

Infarct Volume Predictive of Functional Outcome After Acute Ischemic Stroke

Infarct Volume Predictive of Functional Outcome After Acute Ischemic Stroke

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Variations in reperfusion rates as well as MRI assessments among included studies represent possible limitations of this meta-analysis.

Number of Cigarettes Smoked Daily Tied to Stroke Risk

Number of Cigarettes Smoked Daily Tied to Stroke Risk

There is a strong dose-response relationship between the number of cigarettes smoked daily and ischemic stroke risk among young men.

Rapid Deployment Valve for Aortic Stenosis Ups Stroke Risk

Rapid Deployment Valve for Aortic Stenosis Ups Stroke Risk

For patients with aortic valve stenosis, treatment with a rapid deployment valve is associated with increased rates of new-onset pacemaker implantation and disabling stroke.

Clopidogrel Plus Aspirin Reduces Recurrent Stroke Risk in Patients With Multiple Acute Infarctions

Clopidogrel Plus Aspirin Reduces Recurrent Stroke Risk in Patients With Multiple Acute Infarctions

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Investigators assessed the impact of infarction patterns on the safety and effectiveness of dual antiplatelet therapy with clopidogrel and aspirin.

Demographic Factors Accelerate Decline in Global Cognition and Executive Function Following Stroke

Demographic Factors Accelerate Decline in Global Cognition and Executive Function Following Stroke

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A cohort from the REGARDS study was assessed to measure change in cognition and function following stroke.

Predicting Stroke Subtype Risk With Retinal Microvascular Abnormalities

Predicting Stroke Subtype Risk With Retinal Microvascular Abnormalities

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The results suggest a noninvasive method for predicting individualized risk for certain stroke subtypes.

MIND Diet Linked to Slower Cognitive Decline Among Stroke Survivors

MIND Diet Linked to Slower Cognitive Decline Among Stroke Survivors

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The MIND diet, a combination of the Mediterranean and DASH diets, was associated with a slower rate of cognitive decline among stroke survivors.

Post-Recanalization Stroke Score More Effective Than Baseline Score for Predicting 3-Month Outcome

Post-Recanalization Stroke Score More Effective Than Baseline Score for Predicting 3-Month Outcome

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The investigators of this study evaluated patients who received care between 2008 and 2015, so findings may differ from those receiving care under the current EVT guideline from the American Heart Association Council published in 2015.

Hypercapnic Acidosis Associated With Increased Mortality Risk in Acute Cerebral Injury

Hypercapnic Acidosis Associated With Increased Mortality Risk in Acute Cerebral Injury

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Hypercapnic acidosis may be associated with increased mortality in mechanically ventilated patients with acute cerebral injury.

Successful Reperfusion Linked to Reduced Edema in Acute Ischemic Stroke

Successful Reperfusion Linked to Reduced Edema in Acute Ischemic Stroke

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Reperfusion was associated with reduced brain edema in patients presenting with acute ischemic stroke.

Rate of MI, Stroke Higher After Respiratory Infection

Rate of MI, Stroke Higher After Respiratory Infection

The risk for myocardial infarction or stroke remains higher after laboratory-confirmed Streptococcus pneumoniae or influenza.

Physical, Executive Function Most Affected After Ischemic Stroke

Physical, Executive Function Most Affected After Ischemic Stroke

Worse scores in multiple domains were tied to lower income, female sex, and disability.

CPAP Effective for Sleep Apnea Treatment Following Stroke

CPAP Effective for Sleep Apnea Treatment Following Stroke

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The combined analysis of the neurofunctional scales demonstrated an overall neurofunctional improvement with CPAP.

Assessing and Treating Cognitive, Mood Impairments in Patients With Stroke

Assessing and Treating Cognitive, Mood Impairments in Patients With Stroke

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The ultimate goal of stroke assessment is to enable physicians to make treatment decisions that are individualized and appropriate to the patient's needs, thereby improving patient outcomes.

Social Isolation, Loneliness May Increase AMI, Stroke Risk

Social Isolation, Loneliness May Increase AMI, Stroke Risk

Isolation and loneliness may be associated with increased risk of acute myocardial infarction and stroke.

Biomarker Indicates Brain Tissue at Risk for Stroke in Sickle Cell Disease

Biomarker Indicates Brain Tissue at Risk for Stroke in Sickle Cell Disease

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Using the infarct heat map, the investigators determined that infarct density was higher in the deep white matter and co-localized with the elevated OEF region in the independent prospective cohort.

Code Stroke System Reduces Post-Stroke Epilepsy Risk in Older Adults

Code Stroke System Reduces Post-Stroke Epilepsy Risk in Older Adults

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The adjusted analysis also demonstrated that the code stroke system was associated with a decreased risk for post-stroke epilepsy within 5 years of stroke.

Intensive Blood Pressure Lowering Provides No Mortality Benefit in Acute Intracerebral Hemorrhage

Intensive Blood Pressure Lowering Provides No Mortality Benefit in Acute Intracerebral Hemorrhage

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Investigators conducted a meta-analysis of trials that reported functional outcomes and mortality rates among patients with intracerebral hemorrhage following intensive blood pressure lowering.

Predicting Intracerebral Hemorrhage Outcomes With Peak Perihemorrhagic Edema

Predicting Intracerebral Hemorrhage Outcomes With Peak Perihemorrhagic Edema

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Further research may be necessary to better understand the pathophysiologic mechanisms involved in perihemorrhagic edema evolution and ICH.

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