For patients with ischemic stroke with an unknown time of onset, intravenous alteplase is associated with better functional outcome than placebo.
While developing the hematoma expansion prediction score, associations between hematoma expansion and blend sign, any intrahematoma hypodensity, and time from onset to noncontrast computed tomography <2.5 hours were found.
Congenital Heart Disease, Hispanic Ethnicity Associated With Increased Mortality in Pediatric Arterial Ischemic StrokeMay 21, 2018
The investigators were unable to determine which type of congenital heart disease or which type of ventricular assist device, if used, played a role in mortality outcomes.
The findings from this trial are limited to only ischemic stroke patients with large-vessel occlusion who are deemed appropriate for thrombolysis.
There were no differences between the ceftriaxone and standard care groups in terms of institutional care resources, out-of-pocket expenses, or productivity losses.
Sickle cell trait is not associated with ischemic stroke and should not be relied upon as a sole predictor of stroke in African Americans.
A shortened summary cognitive score consisting of action speed, executive function, and language may help diagnose poststroke NCD.
For adults, frequent sauna bathing is associated with reduced risk of future stroke.
The lack of a comparator group as well as the relatively small patient sample represents potential limitations of this study.
Investigators performed a pre-planned secondary analysis of the open-label, randomized Antihypertensive Treatment of Acute Cerebral Hemorrhage 2 study, specifically on the magnetic resonance images obtained during the intensive blood pressure lowering portion of the trial.
For patients undergoing surgical aortic valve replacement, previous stroke is a risk factor for recurrent ischemic stroke and major adverse cardiovascular events.
Variations in reperfusion rates as well as MRI assessments among included studies represent possible limitations of this meta-analysis.
There is a strong dose-response relationship between the number of cigarettes smoked daily and ischemic stroke risk among young men.
For patients with aortic valve stenosis, treatment with a rapid deployment valve is associated with increased rates of new-onset pacemaker implantation and disabling stroke.
Investigators assessed the impact of infarction patterns on the safety and effectiveness of dual antiplatelet therapy with clopidogrel and aspirin.
A cohort from the REGARDS study was assessed to measure change in cognition and function following stroke.
The results suggest a noninvasive method for predicting individualized risk for certain stroke subtypes.
The MIND diet, a combination of the Mediterranean and DASH diets, was associated with a slower rate of cognitive decline among stroke survivors.
The investigators of this study evaluated patients who received care between 2008 and 2015, so findings may differ from those receiving care under the current EVT guideline from the American Heart Association Council published in 2015.
Hypercapnic acidosis may be associated with increased mortality in mechanically ventilated patients with acute cerebral injury.
Reperfusion was associated with reduced brain edema in patients presenting with acute ischemic stroke.
The risk for myocardial infarction or stroke remains higher after laboratory-confirmed Streptococcus pneumoniae or influenza.
Worse scores in multiple domains were tied to lower income, female sex, and disability.
The combined analysis of the neurofunctional scales demonstrated an overall neurofunctional improvement with CPAP.
The ultimate goal of stroke assessment is to enable physicians to make treatment decisions that are individualized and appropriate to the patient's needs, thereby improving patient outcomes.
Isolation and loneliness may be associated with increased risk of acute myocardial infarction and stroke.
Using the infarct heat map, the investigators determined that infarct density was higher in the deep white matter and co-localized with the elevated OEF region in the independent prospective cohort.
The adjusted analysis also demonstrated that the code stroke system was associated with a decreased risk for post-stroke epilepsy within 5 years of stroke.
Investigators conducted a meta-analysis of trials that reported functional outcomes and mortality rates among patients with intracerebral hemorrhage following intensive blood pressure lowering.
Further research may be necessary to better understand the pathophysiologic mechanisms involved in perihemorrhagic edema evolution and ICH.
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