Vascular Neurology

Predicting Hemorrhage Risk in Patients With Vascular Malformations

Predicting Hemorrhage Risk in Patients With Vascular Malformations

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The investigators of this study did not compare pre- or post-hemorrhage data, precluding their ability to determine the applicability of the findings for improving clinical practice.

Intensive blood pressure control not linked to changes in cerebral perfusion in patients with cerebral small vessel disease

In patients with severe cerebral small vessel disease, a strategy of intensive blood pressure control did not significantly alter whole brain blood flow when compared to standard blood pressure control.

No Reduction in Cerebral Perfusion With Intensive Blood Pressure Lowering

No Reduction in Cerebral Perfusion With Intensive Blood Pressure Lowering

Intensive blood pressure lowering does not reduce cerebral perfusion for patients with severe small vessel disease.

Cerebral Blood Flow Significantly Reduced After Hemodialysis

Cerebral Blood Flow Significantly Reduced After Hemodialysis

In older patients, conventional hemodialysis induces a reduction in cerebral blood flow.

General Anesthesia a Viable Sedation Strategy for Thrombectomy in Stroke: Clinician Takeaway

General Anesthesia a Viable Sedation Strategy for Thrombectomy in Stroke: Clinician Takeaway

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Although several studies have established the use of endovascular therapy with stent retrievers for selected acute stroke as standard of care, best practices surrounding the best sedation strategy remain unclear.

Intracranial Atherosclerotic Disease May Coexist With Stroke Risk Factors

Intracranial Atherosclerotic Disease May Coexist With Stroke Risk Factors

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Screening for coexisting diseases may help identify high-risk patients with intracranial atherosclerotic disease.

Brain Arteriovenous Malformations Linked to <i>KRAS</i> Mutations

Brain Arteriovenous Malformations Linked to KRAS Mutations

Somatic activating KRAS mutations are often found in patients with arteriovenous malformations of the brain.

Subcortical Microinfarcts Associated With Decreased Blood Pressure in Elderly

Subcortical Microinfarcts Associated With Decreased Blood Pressure in Elderly

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Greater yearly declines in systolic and diastolic blood pressure were noted in individuals with subcortical microinfarcts.

Expert Consensus: Managing Bleeding in Patients Taking Oral Anticoagulants

Expert Consensus: Managing Bleeding in Patients Taking Oral Anticoagulants

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The ACC released a new concensus on guiding clinicians in managing acute bleeding for patients treated with OACs.

Induced Hypertension Does Not Improve Outcomes in Subarachnoid Hemorrhage, Cerebral Ischemia

Induced Hypertension Does Not Improve Outcomes in Subarachnoid Hemorrhage, Cerebral Ischemia

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The investigators halted the trial prematurely due to slow recruitment and a lack of treatment efficacy in overall cerebral perfusions.

Bone Mineral Density Associated With Intracranial Aneurysm Presence, Size

Bone Mineral Density Associated With Intracranial Aneurysm Presence, Size

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Patients with the lowest bone mineral density had the largest aneurysm size.

Cardiac Index Affects Cerebral Blood Flow Irrespective of CVD

Cardiac Index Affects Cerebral Blood Flow Irrespective of CVD

In older adults, lower cardiac index is linked to lower cerebral blood blow in the temporal lobe.

Trial Update: Bariatric Surgery vs Dietary Program for Tx of Idiopathic Intracranial Hypertension

Trial Update: Bariatric Surgery vs Dietary Program for Tx of Idiopathic Intracranial Hypertension

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The trial, sponsored by the University of Birmingham, is currently recruiting participants.

Predicting Cerebral Edema Severity After Stroke

Predicting Cerebral Edema Severity After Stroke

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There is some evidence that suggests intravenous thrombolysis for stroke may impair the blood-brain barrier and cause cerebral edema.

Awake Neurologic Testing During Aneurysm Repair Decreases Ischemic Injury Risk

Awake Neurologic Testing During Aneurysm Repair Decreases Ischemic Injury Risk

The treatment of brain aneurysms may be improved with "awake" brain surgery.

Unprovoked Venous Thromboembolism May Be Sign of Occult Cancer

Unprovoked Venous Thromboembolism May Be Sign of Occult Cancer

About 1 in 20 patients with VTE have occult cancer detected within a year.

CSF Pressure Not Directly Linked to Headache in Idiopathic Intracranial Hypertension

CSF Pressure Not Directly Linked to Headache in Idiopathic Intracranial Hypertension

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The study group concluded that the current recommendation for CSF pressure reduction therapy to relieve headaches attributed to IIH should be removed from the International Classification of Headache Disorders 3b criteria.

Cerebral Small Vessel Disease Linked to HTRA1 Mutation

Cerebral Small Vessel Disease Linked to HTRA1 Mutation

Heterozygous mutations may play a role in familial cerebral small vessel disease.

Intravenous Idarucizumab Successfully Reverses Dabigatran

Intravenous Idarucizumab Successfully Reverses Dabigatran

At 90-days, the rate of thrombotic events in both groups was low.

Primary Stroke Center Protocol Significantly Improves Outcomes

Primary Stroke Center Protocol Significantly Improves Outcomes

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Reduced door-to-needle times have been shown to improve outcomes after stroke.

Evaluating Cerebral Blood Flow Velocity During Migraine Headache

Evaluating Cerebral Blood Flow Velocity During Migraine Headache

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Although decreased blood flow velocity correlates with arterial dilatation, studies using transcranial Doppler ultrasound to evaluate intracranial vasodilatation during migraine report conflicting results.

Intracranial Hemorrhage Associated with Arteriovenous Malformations Linked to Better Outcomes

Intracranial Hemorrhage Associated with Arteriovenous Malformations Linked to Better Outcomes

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Compared with other sources of ICH, those associated with arteriovenous malformations had lower odds of death.

In Endovascular Therapy for Stroke, Monitored Anesthesia Is Safe, Effective

In Endovascular Therapy for Stroke, Monitored Anesthesia Is Safe, Effective

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Monitored anesthesia was found to be as safe and effective as general anesthesia in patients undergoing endovascular therapy for stroke.

Headache and Arteriovenous Malformations: Strategies for Identification, Treatment

Headache and Arteriovenous Malformations: Strategies for Identification, Treatment

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Several mechanisms involving trigeminovascular activation are often proposed in the literature as mechanisms underlying nonhemorrhagic headache in patients with AVM.

Ischemic Stroke Risk Elevated in Systemic Lupus Erythematosus

Ischemic Stroke Risk Elevated in Systemic Lupus Erythematosus

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The relative risk of developing ischemic stroke was increased in patients with systemic lupus erythematosus, especially within the first year after diagnosis.

Improving Stroke Diagnosis Accuracy: An Interview With David Newman-Toker, MD, PhD

Improving Stroke Diagnosis Accuracy: An Interview With David Newman-Toker, MD, PhD

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Neurologists need to engage their emergency medicine colleagues to identify protocols and pathways for when to trigger appropriate neurological consultation or initiate acute stroke therapies.

Prevalence of Ischemic Stroke Increasing in Young Adults

Prevalence of Ischemic Stroke Increasing in Young Adults

During the study period, the percentage of people with 3 or more stroke risk factors roughly doubled for all age groups.

Stroke Risk and Serum Uric Acid Levels: Does Gender Play a Role?

Stroke Risk and Serum Uric Acid Levels: Does Gender Play a Role?

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Previous studies have produced contradictory evidence of a link between serum UA and stroke risk, with some pointing to greater risks in women compared with men.

Endovascular Stroke Treatment Shows Sustained Response Up to 2 Years

Endovascular Stroke Treatment Shows Sustained Response Up to 2 Years

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Over 32% of patients were functionally independent at 90 days and 37.1% were functionally independent at 2 years.

Biomarker Identified for Cerebral Small Vessel Disease Burden, Progression

Biomarker Identified for Cerebral Small Vessel Disease Burden, Progression

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Serum neurofilament light chain levels show potential in predicting the burden and progression of cerebral small vessel disease.

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