The investigators of this study did not compare pre- or post-hemorrhage data, precluding their ability to determine the applicability of the findings for improving clinical practice.
Intensive blood pressure control not linked to changes in cerebral perfusion in patients with cerebral small vessel diseaseMarch 21, 2018
In patients with severe cerebral small vessel disease, a strategy of intensive blood pressure control did not significantly alter whole brain blood flow when compared to standard blood pressure control.
Intensive blood pressure lowering does not reduce cerebral perfusion for patients with severe small vessel disease.
In older patients, conventional hemodialysis induces a reduction in cerebral blood flow.
Although several studies have established the use of endovascular therapy with stent retrievers for selected acute stroke as standard of care, best practices surrounding the best sedation strategy remain unclear.
Screening for coexisting diseases may help identify high-risk patients with intracranial atherosclerotic disease.
Somatic activating KRAS mutations are often found in patients with arteriovenous malformations of the brain.
Greater yearly declines in systolic and diastolic blood pressure were noted in individuals with subcortical microinfarcts.
The ACC released a new concensus on guiding clinicians in managing acute bleeding for patients treated with OACs.
The investigators halted the trial prematurely due to slow recruitment and a lack of treatment efficacy in overall cerebral perfusions.
Patients with the lowest bone mineral density had the largest aneurysm size.
In older adults, lower cardiac index is linked to lower cerebral blood blow in the temporal lobe.
The trial, sponsored by the University of Birmingham, is currently recruiting participants.
There is some evidence that suggests intravenous thrombolysis for stroke may impair the blood-brain barrier and cause cerebral edema.
The treatment of brain aneurysms may be improved with "awake" brain surgery.
About 1 in 20 patients with VTE have occult cancer detected within a year.
The study group concluded that the current recommendation for CSF pressure reduction therapy to relieve headaches attributed to IIH should be removed from the International Classification of Headache Disorders 3b criteria.
Heterozygous mutations may play a role in familial cerebral small vessel disease.
At 90-days, the rate of thrombotic events in both groups was low.
Reduced door-to-needle times have been shown to improve outcomes after stroke.
Although decreased blood flow velocity correlates with arterial dilatation, studies using transcranial Doppler ultrasound to evaluate intracranial vasodilatation during migraine report conflicting results.
Compared with other sources of ICH, those associated with arteriovenous malformations had lower odds of death.
Monitored anesthesia was found to be as safe and effective as general anesthesia in patients undergoing endovascular therapy for stroke.
Several mechanisms involving trigeminovascular activation are often proposed in the literature as mechanisms underlying nonhemorrhagic headache in patients with AVM.
The relative risk of developing ischemic stroke was increased in patients with systemic lupus erythematosus, especially within the first year after diagnosis.
Neurologists need to engage their emergency medicine colleagues to identify protocols and pathways for when to trigger appropriate neurological consultation or initiate acute stroke therapies.
During the study period, the percentage of people with 3 or more stroke risk factors roughly doubled for all age groups.
Previous studies have produced contradictory evidence of a link between serum UA and stroke risk, with some pointing to greater risks in women compared with men.
Over 32% of patients were functionally independent at 90 days and 37.1% were functionally independent at 2 years.
Serum neurofilament light chain levels show potential in predicting the burden and progression of cerebral small vessel disease.
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