A placebo-controlled study of smokers with MDD evaluated varenicline with vs without behavioral interventions for smoking cessation.
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As early identification of symptoms and appropriate severity stratification are important for illness management, the aim of this study was to evaluate current data on markers for instability in anorexia nervosa.
In this study, participants were followed for 2 years with the outcomes of interest being height, weight, cardiovascular health, and psychiatric outcomes.
For this study in adults with OUD and insomnia receiving buprenorphine, investigators looked at whether women or men were more likely to be prescribed benzodiazepines.
This study looked at whether youth with ADHD, following 24-HMB recommendations, were less likely to have difficulty concentrating, remembering, or making decisions and making or keeping friends.
Researchers identify 2 major risk factors for bipolar disorder in adulthood.
A study was conducted to determine the effects of switching or augmenting antidepressant therapy in adults with treatment-resistant depression.
In this study, participants underwent cardiorespiratory fitness (CRF) testing using the 6-minute walk test and perceived CRF was evaluated by asking participants what they thought their current aerobic fitness level was.
Investigators searched publication databases through June 2021 for studies evaluating the efficacy of group-based PTSD interventions in the pediatric setting.
Patients with MDD were randomly assigned in a 1:1:1 ratio to receive 1.5 mg daily cariprazine, 3.0 mg daily cariprazine, or placebo for 6 weeks.
Investigators searched publication databases for randomized controlled trials evaluating cognitive training and remediation interventions among patients with MDD.
Data about grade point averages during transitions from early, intermediate, and upper compulsory education and to vocational or university education were sourced from population-based registers in Sweden.
Researchers searched for protective effects in gut microbiota from the pathogenesis of major depressive disorder.
Researchers assessed characteristics and correlates of metabolic syndrome in adolescents with major depressive disorder or bipolar disorder depression.
Researchers evaluated the effect of traumatic events, including PTSD, on treatment adherence and outcomes in eating disorders.
Researchers evaluated the efficacy of dextromorphan-bupropion among patients with major depressive disorder and comorbid anxiety.
Researchers compared the white matter networks of patients with remitted major depressive disorder and remitted bipolar disorder to find disease-specific alterations.
The researchers sought to examine whether inflammation and white matter microstructure play a role in treatment response in major depressive disorder.
Outpatients were recruited at the Instituto Nacional de Psiquiatía (National Institute of Psychiatry) in Mexico and were evaluated for alcohol dependence and major depressive disorder.
Patients with somatoform disorders, major depressive disorder, and healthy controls were recruited between 2016 and 2017 at the Ambulante Psychosoziale Rehabilitation in Austria and Schoen Clinic Roseneck in Germany.
For this study, community-dwelling adults were evaluated for major depressive disorder, generalized anxiety disorder, and global sleep quality over an 18 year period.
This prospective, multi-center, open-label trial, CAN-BIND-1 was conducted between 2012 and 2017.
Investigators sourced data for this study from the Stockholm Major Depressive Disorder Cohort. Between 2010 and 2018, all patients in the Stockholm region who met the criteria for MDD were enrolled in the cohort.
Patients with treatment-resistant major depressive disorder or bipolar disorder without psychotic symptoms received intravenous infusions of 0.5 mg/kg ketamine 3 times per week for 2 weeks.
During the COVID-19 pandemic, ED visits for attempted suicide and suicidal ideation increased, while no clear trend in the rates of ED visit for self-harm were observed.
Patients who had treatment-naïve MDD were recruited in the US between 2007 and 2013 for the Predictors of Remission in Depression to Individual and Combined Treatments (PReDICT) study.
Major depressive episodes reduce visual contrast suppression among patients with depressive disorders, a study shows.
Data for this study were sourced from 4 active treatment arms of 4 randomized, controlled trials conducted by the National Institutes of Health in the United States between 2006 and 2018.
This retrospective cohort study evaluated patient data from patients aged 50 years or older who received an acute course of ECT between 2011 and 2019 and were evaluated for cognition and depression outcomes on the basis of baseline cognitive function.
Previous studies have found that perinatal women have had detriments to sleep and depression during the pandemic; however, all studies to date in the perinatal setting have lacked a comparator group, so robust conclusions about the effect of the COVID-19 pandemic have not been elucidated.
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