Researchers searched for protective effects in gut microbiota from the pathogenesis of major depressive disorder.
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Researchers assessed characteristics and correlates of metabolic syndrome in adolescents with major depressive disorder or bipolar disorder depression.
Researchers evaluated the efficacy of dextromorphan-bupropion among patients with major depressive disorder and comorbid anxiety.
The researchers sought to examine whether inflammation and white matter microstructure play a role in treatment response in major depressive disorder.
Researchers compared the white matter networks of patients with remitted major depressive disorder and remitted bipolar disorder to find disease-specific alterations.
For this study, community-dwelling adults were evaluated for major depressive disorder, generalized anxiety disorder, and global sleep quality over an 18 year period.
Investigators searched publication databases for randomized controlled trials evaluating cognitive training and remediation interventions among patients with MDD.
Outpatients were recruited at the Instituto Nacional de Psiquiatía (National Institute of Psychiatry) in Mexico and were evaluated for alcohol dependence and major depressive disorder.
Patients with somatoform disorders, major depressive disorder, and healthy controls were recruited between 2016 and 2017 at the Ambulante Psychosoziale Rehabilitation in Austria and Schoen Clinic Roseneck in Germany.
Investigators sourced data for this study from the Stockholm Major Depressive Disorder Cohort. Between 2010 and 2018, all patients in the Stockholm region who met the criteria for MDD were enrolled in the cohort.
Patients with treatment-resistant major depressive disorder or bipolar disorder without psychotic symptoms received intravenous infusions of 0.5 mg/kg ketamine 3 times per week for 2 weeks.
Data for this study were sourced from 4 active treatment arms of 4 randomized, controlled trials conducted by the National Institutes of Health in the United States between 2006 and 2018.
Patients who had treatment-naïve MDD were recruited in the US between 2007 and 2013 for the Predictors of Remission in Depression to Individual and Combined Treatments (PReDICT) study.
A cross-sectional family study sought to determine if parents’ transmission of anxiety is sex specific.
Patients with MDD were randomly assigned in a 1:1:1 ratio to receive 1.5 mg daily cariprazine, 3.0 mg daily cariprazine, or placebo for 6 weeks.
A study was conducted to determine the effects of switching or augmenting antidepressant therapy in adults with treatment-resistant depression.
Investigators looked into which treatment fared better for patients with anxiety disorders: a mindfulness-based stress reduction intervention or escitalopram.
A placebo-controlled study of smokers with MDD evaluated varenicline with vs without behavioral interventions for smoking cessation.
The REAL-ESK study was an observational, retrospective, multicenter study conducted in Italy.
For this study, patients with generalized anxiety disorder were recruited from the Nanfang Hospital in China between 2018 and 2020.
The Alpha-Stim-D trial was a noncommercial, multicenter, randomly assigned, parallel group, double-blind trial conducted at 25 primary care practices in the United Kingdom.
Children and adolescents were evaluated for receipt of antipsychotics between 2000 and 2019 in England.
This observational study was conducted by telephone interviews between April and July 2020.
In this study, participants underwent cardiorespiratory fitness (CRF) testing using the 6-minute walk test and perceived CRF was evaluated by asking participants what they thought their current aerobic fitness level was.
Researchers examined associations between polygenic risk scores and neuropsychiatric conditions using data from phenome-wide association studies.
Investigators surveyed adolescents and young adults with self-reported ADHD to determine what proportion already engage in tolerance breaks from their medication, and how often.
Researchers evaluated the effect of traumatic events, including PTSD, on treatment adherence and outcomes in eating disorders.
Researchers identify 2 major risk factors for bipolar disorder in adulthood.
Researchers investigated whether individuals with symptoms of depression were more sensitive to missed opportunities.
Inpatients with persistent depressive disorder were recruited at a German University Hospital for a 10-week inpatient treatment with the Cognitive Behavioral Analysis System of Psychotherapy.
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