Whether major depressive disorder is a comorbidity of bipolar disorder isn’t really known. Researchers built a predictive model of major depressive disorder to bipolar disorder conversion and with the Observational Medical Outcomes Partnership validated the results across a multi-national network of patient databases.
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The researchers sought to estimate the age-specific incidence and prevalence of dementia diagnoses among older adults with schizophrenia in the United States compared to those without serious mental illness.
Researchers compared how patients experiencing a major depressive episode and control participants perceived contrast patterns.
Registries databases were searched for randomized controlled trials published between 1952 and 2020 that evaluated psychological interventions for adults diagnosed with bipolar I or bipolar II disorder.