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Multiple system atrophy is a rare, progressive neurodegenerative condition for which there is currently no cure.

“Since the current generation of psychiatrists has been raised on second-generation antipsychotics and has relatively little experience with first-generation antipsychotics, keeping tardive dyskinesia in mind is not, on the whole, part of their experience or training,” said Christoph U. Correll, MD.

Although evidence of cognitive impairment in MSA is admittedly more limited than in Parkinson disease, it is now substantial enough to address modification of diagnostic criteria to include the potential for cognitive impairment at any stage of the disease.

Debate continues as to whether ocular tremor represents a clinical marker of Parkinson’s disease or a compensatory movement related to other bodily tremors.

Investigators identified a series of prodromal signs that appear anywhere from 1 to 18 years before a clinical diagnosis of SCA2.

New guidelines for progressive supranuclear palsy provide very specific and sensitive criteria that allow for identification of clinical features of the disease at much earlier stages.

A patient should be notified of the possibility of developing an ICD before initiating any dopaminergic treatment for PD, particularly dopamine agonists.

Comorbid psychological conditions affect cognitive function in Parkinson’s disease, and treatment can be complicated by overlapping symptoms.

Research has shown a confounding link between nicotine and reduced risk of Parkinson’s disease.

Closed-loop neurostimulation technology is being investigated for movement disorders, headache, and even some neuropsychiatric disorders.