This prospective, multi-center, open-label trial, CAN-BIND-1 was conducted between 2012 and 2017.
Previous studies have found that perinatal women have had detriments to sleep and depression during the pandemic; however, all studies to date in the perinatal setting have lacked a comparator group, so robust conclusions about the effect of the COVID-19 pandemic have not been elucidated.
Data for this study were sourced from 4 active treatment arms of 4 randomized, controlled trials conducted by the National Institutes of Health in the United States between 2006 and 2018.
Patients with treatment-resistant major depressive disorder or bipolar disorder without psychotic symptoms received intravenous infusions of 0.5 mg/kg ketamine 3 times per week for 2 weeks.
In a case-control study, researchers assessed the potential link between late-onset depression and the risk of developing major cognitive disorder.
This retrospective cohort study evaluated patient data from patients aged 50 years or older who received an acute course of ECT between 2011 and 2019 and were evaluated for cognition and depression outcomes on the basis of baseline cognitive function.
Researchers compared the effects of 4 contemporary ablative neurosurgical procedures on treatment-resistant psychiatric symptoms.