Multimarker inflammatory biosignatures are expected to facilitate diagnosis and predict treatment outcomes for various central nervous system disorders, particularly Alzheimer disease and major depressive disorder.
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Depression of some degree is prevalent in a majority of patients with ALS.
A number of psychiatric and neurodegenerative diseases are associated with abnormal imaging findings, which can help psychiatrists reach a diagnosis.
Researchers sought to investigate the association between lower retinal nerve fiber layer thickness, a marker of neurodegeneration, with clinically relevant depressive symptoms and depressive symptoms over time.
Among 5.2% of cases of early-onset dementia, most were either alcohol-related by definition or had an additional diagnosis of alcohol use disorders.
Given the limited data is available on bone health of patients with NMOSD-AQP4, researchers aimed to investigate their risk for fracture and bone loss.
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