Investigators searched publication databases for randomized controlled trials evaluating cognitive training and remediation interventions among patients with MDD.
Your search for major depressive disorder returned 110 results
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Researchers seek to evaluate whether trauma-focused therapy adjunctive to treatment as usual (TAU) leads to a greater reduction of depressive symptoms posttreatment vs TAU exclusively in patients with major depressive disorder with childhood trauma.
Researchers evaluated the efficacy of dextromorphan-bupropion among patients with major depressive disorder and comorbid anxiety.
Researchers searched for protective effects in gut microbiota from the pathogenesis of major depressive disorder.
For this study, community-dwelling adults were evaluated for major depressive disorder, generalized anxiety disorder, and global sleep quality over an 18 year period.
Patients with somatoform disorders, major depressive disorder, and healthy controls were recruited between 2016 and 2017 at the Ambulante Psychosoziale Rehabilitation in Austria and Schoen Clinic Roseneck in Germany.
This prospective, multi-center, open-label trial, CAN-BIND-1 was conducted between 2012 and 2017.
Investigators report the findings from a study assessing the impact of insomnia on clinical outcomes in patients with major depressive disorder.
An additional 53.2 million cases of major depressive disorder and 76.2 million cases of anxiety disorders globally were estimated due to the COVID-19 pandemic.
AXS-05 consists of dextromethorphan, an NMDA receptor antagonist, and bupropion, a norepinephrine and dopamine reuptake inhibitor.
Patients with MDD were randomly assigned in a 1:1:1 ratio to receive 1.5 mg daily cariprazine, 3.0 mg daily cariprazine, or placebo for 6 weeks.
Better baseline cardiovascular health and improvement in cardiovascular health over seven years tied to lower 19-year risk for depression
The Alpha-Stim-D trial was a noncommercial, multicenter, randomly assigned, parallel group, double-blind trial conducted at 25 primary care practices in the United Kingdom.
Investigators sought to assess associations for US Army soldiers bullied by fellow soldiers with mental health outcomes.
American College of Physicians recommends monotherapy with cognitive therapy or second-generation antidepressant for patients in acute phase of moderate-to-severe depression
Deep learning, multidiagnostic model shows high accuracy before clinical examination
Researchers compared grey matter volume patterns in adult patients with attention-deficit/hyperactivity disorder and bipolar disorder.
Researchers compared the white matter networks of patients with remitted major depressive disorder and remitted bipolar disorder to find disease-specific alterations.
However, no corresponding increase seen in mental health treatment
Researchers sought to determine the time course and state dependency of serum amyloid-beta levels in older patients with depression.
Adults with major depressive disorder and a history of childhood trauma can still benefit from recommended depression treatments.
A cross-sectional family study sought to determine if parents’ transmission of anxiety is sex specific.
Inpatients with persistent depressive disorder were recruited at a German University Hospital for a 10-week inpatient treatment with the Cognitive Behavioral Analysis System of Psychotherapy.
For this study, patients with generalized anxiety disorder were recruited from the Nanfang Hospital in China between 2018 and 2020.
In a case-control study, researchers assessed the potential link between late-onset depression and the risk of developing major cognitive disorder.
Researchers examined the effect of neuropeptides orexin-A, ghrelin, and neuropeptide Y on hypersomnia and hyperphagia. Both symptoms are more common in people with bipolar disorder.
Whether major depressive disorder is a comorbidity of bipolar disorder isn’t really known. Researchers built a predictive model of major depressive disorder to bipolar disorder conversion and with the Observational Medical Outcomes Partnership validated the results across a multi-national network of patient databases.
Investigators assessed the safety and efficacy of lumateperone for the treatment of bipolar I and II disorders in patients experiencing major depressive episodes.
Researchers sought to examine the relationship between depressive symptoms and pain in U.S. veterans 50 years of age or older.
Cognitive behavioral therapy for insomnia (CBT-I) has an overall benefit in the prevention of incident and recurrent major depression in older adults with insomnia disorder.
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