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Your search for major depressive disorder returned 5 results

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Neurobehavioral Disorders

Spravato Approved for MDD With Acute Suicidal Ideation or Behavior

The approval was based on the ASPIRE I and II trials that compared the efficacy and safety of esketamine, an N-methyl-D-aspartate receptor antagonist, to placebo in 449 adults with moderate to severe MDD who had active suicidal ideation and intent.
Neuromuscular Disorders

Zolgensma Benefits Observed in Presymptomatic SMA Patients

The phase 3 SPR1NT trial is an ongoing open-label, single-arm study evaluating onasemnogene in presymptomatic patients (≤6 weeks of age) with a genetic diagnosis of SMA and 2 or 3 copies of survival motor neuron 2 gene.
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