Investigators conducted a systematic review of studies published between January 1, 2020 and January 29, 2021 that estimated the prevalence of major depressive disorder and anxiety disorders during the COVID-19 pandemic.
Investigators report the findings from a study assessing the impact of insomnia on clinical outcomes in patients with major depressive disorder.
While the relationship between current mood state and cognitive impairment is unclear, more severe depression has been linked to greater impairment.
This study highlights the importance of transdiagnostic approaches to psychiatry.
Overall, in all patients with MDD, sleep ultradian cycle number was positively associated with REMS percentage, REMS duration, and REMS/NREMS ratio and negatively associated with REM latency.
Polygenic risk scores predict the progression from unipolar depression to bipolar or psychiatric disorders.