AXS-05 consists of dextromethorphan, an NMDA receptor antagonist, and bupropion, a norepinephrine and dopamine reuptake inhibitor.
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Psilocybin has been shown to have antidepressant properties. With direct comparisons between psilocybin and established treatments for depression lacking, the study researchers looked at psilocybin and escitalopram.
Researchers from Dalhousie University in Canada searched publication databases through September of 2020 for articles on ADHD, attention deficit disorder, bipolar disorder, and affective psychosis.
The researchers sought to estimate the age-specific incidence and prevalence of dementia diagnoses among older adults with schizophrenia in the United States compared to those without serious mental illness.
Researchers compared how patients experiencing a major depressive episode and control participants perceived contrast patterns.
A survey of health care providers found a lack of knowledge on idiopathic hypersomnia (IH) among physicians, and that the disorder is often misdiagnosed. We spoke with Richard Bogan, MD, FCCP, FAASM, associate clinical professor at the University of the South Carolina School of Medicine about IH and criteria for diagnosing this sleep disorder.
The researchers evaluated the various impacts of the concurrent COVID-19 and opioid epidemics, taking into consideration the severely restricted access to chronic pain management.
While neurological and psychiatric sequelae of COVID-19 have been reported, more data are needed to adequately assess the effects of COVID-19 on brain health.
The phase 3 SPR1NT trial is an ongoing open-label, single-arm study evaluating onasemnogene in presymptomatic patients (≤6 weeks of age) with a genetic diagnosis of SMA and 2 or 3 copies of survival motor neuron 2 gene.
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