This prospective, multi-center, open-label trial, CAN-BIND-1 was conducted between 2012 and 2017.
Previous studies have found that perinatal women have had detriments to sleep and depression during the pandemic; however, all studies to date in the perinatal setting have lacked a comparator group, so robust conclusions about the effect of the COVID-19 pandemic have not been elucidated.
In a retrospective, observational study, researchers evaluated clinical characteristics of LoHD and assessed whether symptoms are influenced solely on genetics or other factors.
Using a comprehensive neuropsychological battery and other measures of motor functioning, researchers examined the relationship between cognitive and clinical factors in adult patients with type 3 SMA.
Data for this study were sourced from 4 active treatment arms of 4 randomized, controlled trials conducted by the National Institutes of Health in the United States between 2006 and 2018.
A model comprising 6 clinical variables could be used to guide lithium dosage.
Alzheimer's Disease and Dementia
Researchers sought to assess the clinical prevalence of Alzheimer disease in patients with leprosy, also known as Hansen’s disease, and inflammasome activity.
Patients with treatment-resistant major depressive disorder or bipolar disorder without psychotic symptoms received intravenous infusions of 0.5 mg/kg ketamine 3 times per week for 2 weeks.
In a prospective cohort study, researchers assessed whether adverse childhood experiences may increase the risk for multiple sclerosis in women.
In a case-control study, researchers assessed the potential link between late-onset depression and the risk of developing major cognitive disorder.