A survey of health care providers found a lack of knowledge on idiopathic hypersomnia (IH) among physicians, and that the disorder is often misdiagnosed. We spoke with Richard Bogan, MD, FCCP, FAASM, associate clinical professor at the University of the South Carolina School of Medicine about IH and criteria for diagnosing this sleep disorder.
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This genome-wide associated study expanded on the gene-environment correlation for childhood maltreatment and causal relationship between childhood maltreatment and health.
People with epilepsy are more likely to experience psychiatric comorbidities, which can have a highly negative effect on their condition, their mental state, and their overall quality of life. What are some of the effects stress and depression can have on a patient’s epilepsy?
Jacqueline T. Bernard, MD, FAAN, neurologist, associate professor of neurology, quality chief, and clinical vice-chair in the School of Medicine at Oregon Health & Science University, Portland, discusses promising research in multiple sclerosis and neuromyelitis optica spectrum disorders that was presented at the American Academy of Neurology 2021 Virtual Annual Meeting.
Psilocybin has been shown to have antidepressant properties. With direct comparisons between psilocybin and established treatments for depression lacking, the study researchers looked at psilocybin and escitalopram.
Investigators conducted a survey to assess the incidence of COVID-19 in patients with multiple sclerosis as well as the influence of their comorbidities and treatments on outcomes.
AXS-05 consists of dextromethorphan, an NMDA receptor antagonist, and bupropion, a norepinephrine and dopamine reuptake inhibitor.
Researchers compared how patients experiencing a major depressive episode and control participants perceived contrast patterns.
For patients with MDD, the change in scores for depression at six weeks does not differ significantly with psilocybin or psilocybin plus escitalopram.
The researchers evaluated the various impacts of the concurrent COVID-19 and opioid epidemics, taking into consideration the severely restricted access to chronic pain management.
While neurological and psychiatric sequelae of COVID-19 have been reported, more data are needed to adequately assess the effects of COVID-19 on brain health.
To evaluate whether patients with isolated dystonia are at an increased risk for suicidal behavior, researchers administered an anonymous electronic survey.
The researchers sought to estimate the age-specific incidence and prevalence of dementia diagnoses among older adults with schizophrenia in the United States compared to those without serious mental illness.
For people with dementia with symptoms of depression, without a MDD, nondrug interventions are more efficacious than drug interventions.
The phase 3 SPR1NT trial is an ongoing open-label, single-arm study evaluating onasemnogene in presymptomatic patients (≤6 weeks of age) with a genetic diagnosis of SMA and 2 or 3 copies of survival motor neuron 2 gene.
A team of researchers sought to investigate the bidirectional relationship between multiple sclerosis and major depressive disorder with Mendelian randomization.
More than half of individuals with prior COVID-19 illness have met the criteria for symptoms of major depressive disorder.
Researchers from Dalhousie University in Canada searched publication databases through September of 2020 for articles on ADHD, attention deficit disorder, bipolar disorder, and affective psychosis.
Study researchers investigated the optimal sleep strategies for cognition and their underlying mechanisms.
Study researchers sought to address the gap in research regarding the association between poor sleep and executive function in children with ASD, ADHD, or typical development
While treatment for mood stabilization in bipolar disorder is most commonly lithium, all patients do not respond to such treatment. The authors of this study investigated what causes lithium resistance.
Awareness of urinary tract infection among individuals with multiple sclerosis is critical in diagnosis, management, and prophylaxis in this population.
The goals of this study were to identify functional connectome fingerprints that predict symptom improvement with any treatment and with specific treatment.
When treating a patient with peripheral neuropathy and weakness of unknown origin, it is important for primary care providers to consider Charcot-Marie-Tooth disease as a differential diagnosis.
The researchers analyzed data from a large randomized noninferiority trial that compared theta-burst stimulation and high-frequency (10 Hz) rTMS delivered to the left dorsolateral prefrontal cortex.
Researchers analyzed the clinical profile of sleep-related dissociative disorder cases and data that supports its inclusion in the parasomnias section of the International Classification of Sleep Disorders.
Recently updated diagnostic criteria for fibromyalgia that reduce the underdiagnosis in men had not been implemented during these studies.
Dr Amit Akirov examines the evidence suggesting associations between migraine and major depressive disorder (MDD).
Fatigue is considered a multidimensional symptom of multiple sclerosis that remains one of the least understood and among the most difficult to diagnose and manage. This article explores current understanding of the pathophysiologic mechanisms of fatigue in multiple sclerosis and its differential diagnosis, both of which are critical for individualized management.
A systematic scoping review examines the literature about the influence of sleep disorders and disturbance on pain outcomes among US veterans with chronic nonmalignant pain.
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