The phase 3 SPR1NT trial is an ongoing open-label, single-arm study evaluating onasemnogene in presymptomatic patients (≤6 weeks of age) with a genetic diagnosis of SMA and 2 or 3 copies of survival motor neuron 2 gene.
Your search for major depressive disorder returned 206 results
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A team of researchers sought to investigate the bidirectional relationship between multiple sclerosis and major depressive disorder with Mendelian randomization.
More than half of individuals with prior COVID-19 illness have met the criteria for symptoms of major depressive disorder.
Researchers from Dalhousie University in Canada searched publication databases through September of 2020 for articles on ADHD, attention deficit disorder, bipolar disorder, and affective psychosis.
Study researchers investigated the optimal sleep strategies for cognition and their underlying mechanisms.
Study researchers sought to address the gap in research regarding the association between poor sleep and executive function in children with ASD, ADHD, or typical development
While treatment for mood stabilization in bipolar disorder is most commonly lithium, all patients do not respond to such treatment. The authors of this study investigated what causes lithium resistance.
Awareness of urinary tract infection among individuals with multiple sclerosis is critical in diagnosis, management, and prophylaxis in this population.
The goals of this study were to identify functional connectome fingerprints that predict symptom improvement with any treatment and with specific treatment.
When treating a patient with peripheral neuropathy and weakness of unknown origin, it is important for primary care providers to consider Charcot-Marie-Tooth disease as a differential diagnosis.
The researchers analyzed data from a large randomized noninferiority trial that compared theta-burst stimulation and high-frequency (10 Hz) rTMS delivered to the left dorsolateral prefrontal cortex.
Researchers analyzed the clinical profile of sleep-related dissociative disorder cases and data that supports its inclusion in the parasomnias section of the International Classification of Sleep Disorders.
Recently updated diagnostic criteria for fibromyalgia that reduce the underdiagnosis in men had not been implemented during these studies.
Dr Amit Akirov examines the evidence suggesting associations between migraine and major depressive disorder (MDD).
A systematic scoping review examines the literature about the influence of sleep disorders and disturbance on pain outcomes among US veterans with chronic nonmalignant pain.
The researchers compared Google search queries for the term “insomnia” from April and May 2020 to the same months in 2017, 2018, and 2019.
This study addresses the question of whether prescription opioid medications has a potentially causal role in the risk for depression and anxiety disorder.
Can pain intensity scores predict psychosocial outcomes longitudinally? This study examines that question.
Cerebral MRI data suggest that neurological symptoms and cognitive impairment may be common among patients with an acute TTP event.
Investigating whether serial ketamine treatments change functional connectivity between limbic structures and resting-state networks.
Exploring the risk of alcohol use disorders in patients with insomnia.
Proinflammatory cytokines, tryptophan catabolites, and the gut-brain axis may have key roles in chronic fatigue and depression in patients with multiple sclerosis.
The comorbidity of depressive disorders and late-life neurodegenerative diseases including Alzheimer disease has been widely reported. This study looks into whether there is a causal relationship existing between both or, if their co-occurrence is due to confounding or common risk factors, such as aging.
Study findings present 71% of patients with new-onset super refractory status epilepticus as having good or fair outcomes at long-term follow-up.
Disease course, fatigue, self-efficacy, and diet and exercise are major determinants of unemployment for patients with MS.
Researchers performed a double-blind randomized study to investigate the efficacy of tDCS as an augmentation strategy to sertraline in the treatment of vascular depression.
This study highlights the importance of transdiagnostic approaches to psychiatry.
Serotonergic antidepressants are effective for sleep disturbances in perimenopausal and postmenopausal women even without major depressive disorder.
Patients received 40 Hz gamma tACS to provide data on the use of varying stimulation periods.
Researchers conducted a study to evaluate the validity of, and satisfaction with, the Cognition KIT DSST mobile app in patients with major depressive disorder.
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