Neurobehavioral Disorders
Data for this study were sourced from 4 active treatment arms of 4 randomized, controlled trials conducted by the National Institutes of Health in the United States between 2006 and 2018.
Neurobehavioral Disorders
A model comprising 6 clinical variables could be used to guide lithium dosage.
Alzheimer's Disease and Dementia
Researchers sought to assess the clinical prevalence of Alzheimer disease in patients with leprosy, also known as Hansen’s disease, and inflammasome activity.
Neurobehavioral Disorders
Patients with treatment-resistant major depressive disorder or bipolar disorder without psychotic symptoms received intravenous infusions of 0.5 mg/kg ketamine 3 times per week for 2 weeks.
Multiple Sclerosis
In a prospective cohort study, researchers assessed whether adverse childhood experiences may increase the risk for multiple sclerosis in women.
Neurocognitive Disorders
In a case-control study, researchers assessed the potential link between late-onset depression and the risk of developing major cognitive disorder.
MeetingInsight
The American Academy of Neurology hosted its 74th annual meeting in Seattle, Washington. Michael S. Okun, MD, shares his key takeaways from the plethora of sessions discussing advancements in the management of “off” episodes for patients with Parkinson disease. New drug delivery systems and formulations for carbidopa/levodopa (CD/LD) are among the exciting changes from the 2022 AAN meeting.
HowToTreat
Spinal muscular atrophy is one of the most common causes of infant mortality. Historically, SMA treatment consisted of supportive care only. The arrival of disease-modifying therapies has made a major impact on the prognosis for patients with SMA. This article highlights therapies approved by the FDA, such as survival motor neuron 2 (SMN2) modulators, SMN1 gene therapy, and the use of newborn screening to commence treatment in the pre-symptomatic period.
Neurobehavioral Disorders
The US Preventive Services Task Force (USPSTF) recommends screening for major depressive disorder (MDD) in adolescents aged 12 to 18 years, and recommends anxiety screening for children aged 8 to 18 years.
Alzheimer's Disease and Dementia
Researchers sought to explore the relationship between lithium use and the incidence of dementia/dementia subtypes.