This was a study protocol for a phase II pilot feasibility study that will assess the feasibility of ketamine for depression in patients with advanced life-limiting illnesses.
Ensemble is an AI-powered digital mental health coach app designed to address the symptoms of MDD or GAD.
Patients with depression can live with symptoms for a long period of time before finding an option that works. One possibility for patients who are unable to find relief through pharmacology is transcranial magnetic stimulation. An expert offers his view on this form of treatment.
Serotonergic antidepressants are effective for sleep disturbances in perimenopausal and postmenopausal women even without major depressive disorder.
Migraine and Headache
Dr Amit Akirov examines the evidence suggesting associations between migraine and major depressive disorder (MDD).
A team of researchers sought to investigate the bidirectional relationship between multiple sclerosis and major depressive disorder with Mendelian randomization.
More than half of individuals with prior COVID-19 illness have met the criteria for symptoms of major depressive disorder.
The goals of this study were to identify functional connectome fingerprints that predict symptom improvement with any treatment and with specific treatment.
AXS-05 consists of dextromethorphan, an NMDA receptor antagonist, and bupropion, a norepinephrine and dopamine reuptake inhibitor.
The researchers analyzed data from a large randomized noninferiority trial that compared theta-burst stimulation and high-frequency (10 Hz) rTMS delivered to the left dorsolateral prefrontal cortex.