AAIC 2015

Investigational Neurotransmitter May Improve Cognition in Alzheimer's

Investigational Neurotransmitter May Improve Cognition in Alzheimer's

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Promising cognitive-enhancing agents are being investigated.

Exercise May Curb Symptoms of Alzheimer's, Mild Cognitive Impairment

Exercise May Curb Symptoms of Alzheimer's, Mild Cognitive Impairment

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Walking, running or swimming may reduce a range of symptoms of neurodegenerative disorders.

Antibodies Targeting Alzheimer's May Benefit Other Prion Diseases

Antibodies Targeting Alzheimer's May Benefit Other Prion Diseases

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Monoclonal antibodies targeting tau and beta amyloid in Alzheimer's disease may also benefit other neurodegenerative diseases.

Most Dementia Patients Prescribed Multiple Psychotropic Drugs

Most Dementia Patients Prescribed Multiple Psychotropic Drugs

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Younger, female patients were most associated with psychotropic polypharmacy.

AVP-923 Significantly Reduces Agitation in Alzheimer's Disease

AVP-923 Significantly Reduces Agitation in Alzheimer's Disease

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Phase-2 study results suggest AVP-923 has meaningful effects in reducing agitation.

Aducanumab Fails to Show Significant Effect on Alzheimer's Progression

Aducanumab Fails to Show Significant Effect on Alzheimer's Progression

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Results from Biogen's PRIME study indicated that higher doses were more effective at destroying beta amyloid.

Amyloid PET Scans May Inform Dementia Treatments

Amyloid PET Scans May Inform Dementia Treatments

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Clinical trials are underway to evaluate if access to amyloid PET scans affects treatment decisions in dementia.

Diagnostic Tool for Neurocognitive Disorders Will Be Evaluated in Trial

Diagnostic Tool for Neurocognitive Disorders Will Be Evaluated in Trial

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Researchers have begun enrolling 800 patients in a trial to test the accuracy of the PredictND tool.

Solanezumab May Have Modest Effect on Alzheimer's Disease

Solanezumab May Have Modest Effect on Alzheimer's Disease

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Benefit seen in the early treatment group could not be recovered by those for whom treatment was delayed.

Cognitive Impairment Progresses More Rapidly in Women

Cognitive Impairment Progresses More Rapidly in Women

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Differences in brain structure, disease progression and biological characteristics may play a role.

Academic Performance in Childhood Predicts Dementia Risk

Academic Performance in Childhood Predicts Dementia Risk

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Early academic performance may better indicate cognitive reserve than formal education and occupational complexity.

Alzheimer's Diagnosis Among Baby Boomers Expected to Soar

Alzheimer's Diagnosis Among Baby Boomers Expected to Soar

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By 2050, 50% of baby boomers are expected to be diagnosed with Alzheimer's.

New Compound May Prevent Beta Amyloid, Tau Misfolding

New Compound May Prevent Beta Amyloid, Tau Misfolding

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Results suggested that TRV 101 prevents oligomerization activity against both beta amyloid and tau.

Saliva May Help Distinguish Between Forms of Cognitive Impairment

Saliva May Help Distinguish Between Forms of Cognitive Impairment

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High levels of both metabolites were linked to worse working memory in normally aging people.

Potential Biomarkers May Predict Cognitive Impairment in Alzheimer's

Potential Biomarkers May Predict Cognitive Impairment in Alzheimer's

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The biomarkers may be useful for the design of clinical trials.

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