AAN 2015

Interactive Checklist, Financial Incentive Improves Stroke Quality Care

Interactive Checklist, Financial Incentive Improves Stroke Quality Care

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The checklist included reminders for time-sensitive measures.

Topical NSAID Gel May Relieve Migraine Pain

Topical NSAID Gel May Relieve Migraine Pain

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The topical gel may be suitable for patients who experience gastrointestinal side effects from oral NSAIDs.

High-Dose Biotin Drug Improves Progressive Multiple Sclerosis Symptoms

High-Dose Biotin Drug Improves Progressive Multiple Sclerosis Symptoms

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Investigational multiple sclerosis drug MD1003 delivers 300 mg/day of biotin, a huge increase the usually recommended dose of 30-100 mcg/day.

APOE ε2 Linked to Milder Alzheimer's Pathology, Cognitive Impairment

APOE ε2 Linked to Milder Alzheimer's Pathology, Cognitive Impairment

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Compared with APOE ε4, APOE ε2 seems to have an indirect effect on cognition by influencing AD pathology.

Diary App Helps Track Disease Progress in Parkinson's Patients

Diary App Helps Track Disease Progress in Parkinson's Patients

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The app's data easily exports so that physicians have access to accurate, long- and short-term outcomes for patients.

Better Migraine Knowledge Needed Among Primary Care Providers

Better Migraine Knowledge Needed Among Primary Care Providers

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Uncertainty about when to order imaging studies, existing guidelines on migraine preventive treatments common.

Virtual Reality Offers Window Into Parkinson's Psychosis

Virtual Reality Offers Window Into Parkinson's Psychosis

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Common Parkinson's hallucinations replicated using Oculus Rift headset.

Suvorexant Effective for Insomnia in Elderly Patients

Suvorexant Effective for Insomnia in Elderly Patients

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30 mg of suvorexant improved PRO and PSG measures of sleep maintenance and sleep onset at the earliest time points.

Alcohol Consumption Linked to Lower MS Disability

Alcohol Consumption Linked to Lower MS Disability

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Those who drank larger amounts of hard alcohol had the strongest association with lower EDSS.

Post-Stroke Cognitive Decline Worse with Sleep Apnea

Post-Stroke Cognitive Decline Worse with Sleep Apnea

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Sleep problems are common in patients with stroke and may contribute to declines in cognitive performance.

Maternal Mortality, Morbidity Greater with Epilepsy

Maternal Mortality, Morbidity Greater with Epilepsy

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Personalized obstetrical care may be warranted during intrapartum period.

AAN President Advocates Collaboration for Growth of Neurology

AAN President Advocates Collaboration for Growth of Neurology

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Outgoing AAN president Timothy Pedley, MD, spoke of greater utilization of advanced practice professionals to better serve patients.

Transcranial Direct Current Stimulation May Improve Aphasia Outcomes

Transcranial Direct Current Stimulation May Improve Aphasia Outcomes

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Speech impairment previously thought irreversible show incremental improvement with the experimental treatment.

Novel Technique Distinguishes Between ALS, Mimic Disorders

Novel Technique Distinguishes Between ALS, Mimic Disorders

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Threshold-tracking transcranial magnetic stimulation could be a useful diagnostic technique in the clinical setting.

New Multiple Sclerosis Model Visualizes Disease Course

New Multiple Sclerosis Model Visualizes Disease Course

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A topographical model of multiple sclerosis uses animation to illustrate the continuum of the disease.

Correlation Found Between Cortical Thickness, Pain Threshold in Migraine

Correlation Found Between Cortical Thickness, Pain Threshold in Migraine

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The positive correlation could mean that migraineurs are unable to direct attention away from painful stimuli.

Agressive Normothermia After Severe TBI May Improve Outcomes

Agressive Normothermia After Severe TBI May Improve Outcomes

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In-hospital mortality was significantly lower despite longer overall stays.

Breath Powered Sumatriptan System Delivers Sustained Migraine Relief

Breath Powered Sumatriptan System Delivers Sustained Migraine Relief

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The well-tolerated treatment helped sustain migraine relief more than 48-hours post-dose.

Once-Daily Antiepileptic Monotherapy Reduces Healthcare Costs

Once-Daily Antiepileptic Monotherapy Reduces Healthcare Costs

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Total annual healthcare costs per patient increase incrementally with each dose.

Single Seizure Clinic Model Effective in Evaluating Epilepsy

Single Seizure Clinic Model Effective in Evaluating Epilepsy

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Waiting times for assessment were reduced by approximately 70% compared with the standard model.

Aptiom Promising as Monotherapy for Partial Onset Seizures

Aptiom Promising as Monotherapy for Partial Onset Seizures

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FDA is reviewing a supplemental new drug application to expand the indication for eslicarbazepine acetate (ESL) as a monotherapy.

Multiple Sclerosis Relapse, Disability Progression After Ceasing Therapy

Multiple Sclerosis Relapse, Disability Progression After Ceasing Therapy

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Nearly 40% of clinically-stable patients who stopped taking medication recorded a relapse or disability progression.

Multiple Sclerosis Patients Favor Marijuana Legalization

Multiple Sclerosis Patients Favor Marijuana Legalization

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People with MS that currently use marijuana are likely to report higher levels of disability and more recent relapse.

Generalized Tonic-Clonic Seizure Detection System Shows Promise

Generalized Tonic-Clonic Seizure Detection System Shows Promise

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The EMG device is discreet and easy to wear, weighing only 6.5 ounces.

New Guidelines for Treatment of First Seizure

New Guidelines for Treatment of First Seizure

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The guidelines encourage doctors to have a meaningful conversation with their patients to evaluate risks and benefits of treatment.

Motor Network Stimulation Shows Promise for Modulating Motor Excitability

Motor Network Stimulation Shows Promise for Modulating Motor Excitability

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Entire network stimulation may better improve motor excitability vs. primary motor cortex stimulation alone.

Psychiatric Symptoms Predict Recovery After Concussion

Psychiatric Symptoms Predict Recovery After Concussion

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Screening for post-concussive psychiatric symptoms could help shorten recovery.

Younger Children Recover Faster from Concussion than Adolescents

Younger Children Recover Faster from Concussion than Adolescents

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Psychiatric comorbidities, which often aren't diagnosed until teenage years, seemed to attribute to prolonged recoveries.

Phenytoin May Have Applications for Multiple Sclerosis

Phenytoin May Have Applications for Multiple Sclerosis

The news comes after an experimental drug was found to restore myelin in patients with acute optic neuritis.

AAN 2015: What You Can Expect to See, Hear, and Learn

AAN 2015: What You Can Expect to See, Hear, and Learn

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Natalia Rost, MD, shares her thoughts on the upcoming agenda for AAN 2015.

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