Multiple Sclerosis Disability, Fatigue Reduced With Caffeine Intake
Disability severity and fatigue were both lower in patients with multiple sclerosis who consumed caffeine.
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Caffeine intake may reduce multiple sclerosis (MS)-related disability and fatigue, according to new research presented at the 2018 ACTRIMS Forum in San Diego, California.
Mohammad Bagher Maljaie, from the Isfahan University of Medical Sciences, Isfahan, Iran, and colleagues recruited 126 patients with MS (42 with relapsing remitting MS [RRMS], 42 with primary progressive MS, and 42 with secondary progressive MS [SPMS]) to participate in a 168-item food frequency questionnaire that examined dietary intake of caffeine. Medical history, Expanded Disability Status Scale (EDSS) score, and fatigue questionnaire responses were also recorded.
Overall, mean EDSS and fatigue scale scores were worse in patients with secondary progressive MS and primary progressive MS compared with RRMS. Caffeine intake was significantly associated with lower EDSS scores in the RRMS subgroup (P =.031) and lower fatigue scores in all participants (P =.028).
“Caffeine consumption may exert a protective role against [MS],” concluded the researchers. Future studies should recruit a larger and more diverse population to prove the correlation.
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Maljaie MB, Shaygannejad V, Moosavian SP, Mirmosayyeb O. Relationship between caffeine intake, EDSS, and fatigue scale in patients with multiple sclerosis. Presented at: ACTRIMS Forum 2018; February 1-3, 2018; San Diego, CA. Abstract #P240.