Generic Name and Formulations:
Tetanus and reduced diphtheria toxoids, acellular pertussis vaccine; aluminum phosphate adsorbed; susp for IM inj; contains 2-phenoxyethanol and traces of formaldehyde, glutaraldehyde.
Sanofi Pasteur, Inc.
Indications for ADACEL:
Diphtheria, tetanus, and pertussis booster immunization in persons 10–64 years of age.
Adults and Children:
<10yrs or ≥65yrs: not recommended. 10–64yrs (≥5yrs after last dose of tetanus toxoid, diphtheria toxoid, and/or pertussis-containing vaccine): 0.5mL IM once into deltoid muscle.
Anaphylaxis associated with any previous diptheria, tetanus, pertussis vaccine. Encephalopathy within 7 days after previous pertussis-containing vaccine.
Progressive or unstable neurologic disorders. Guillain-Barre syndrome (within 6 weeks) of previous tetanus vaccination. Previous Arthus-type hypersensitivity reaction: not recommended until ≥10yrs after prior dose of tetanus toxoid-containing vaccine. Immunodeficiency. Risk of syncope. Have epinephrine inj (1:1000) available. Latex allergy (prefilled syringes). Pregnancy (Cat.C). Nursing mothers.
Concomitant vaccines: see full labeling. Immunosuppressants (eg, radiation, chemotherapy, high-dose steroids): may get suboptimal response.
Local reactions, headache, body ache or muscle weakness, tiredness, chills, fever, GI upset.
Register pregnant patients exposed to Adacel by calling (800) 822-2463.
Single-dose vials—5, 10; Single-dose prefilled syringes—5
Neurology Advisor Articles
- FDA Approves Aimovig for Migraine Prevention
- Prediction Algorithm Stratifies ICH Patients at Risk for Hematoma Expansion
- Sports-Related Concussion Outcomes Predicted With Serum Neurofilament Light
- FDA Fast-Tracks Treatment for Autism Spectrum Disorder
- Psychological Therapies May Help Older Adults With Chronic Pain
- Amyloid Positivity Increases Risk for Cognitive Impairment in Dementia-Free Patients
- Valproic Acid-Related Adverse Fetal Outcomes May Be Linked to Placental Effects
- Risk of Dementia Up for Older Adults With Lowest Wealth
- Language Used in Medical Record Can Affect Patient Care
- Mortality in Alzheimer Disease Not Strongly Associated With Antipsychotics