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Critical Illness and the Brain: Managing Risk for Cognitive Adverse Effects

Critical Illness and the Brain: Managing Risk for Cognitive Adverse Effects

The results highlight the importance of evaluating and monitoring cognitive function in individuals with recent critical illness or major infections, especially if they are already at risk for dementia.

Latest in Alzheimer's Disease and Dementia

Alzheimer's Disease and Dementia Researchers Identify Amyloid-β Pathology in Several Primary Progressive Aphasia Variants

Researchers Identify Amyloid-β Pathology in Several Primary Progressive Aphasia Variants

Primary progressive aphasia (PPA) classification system suggests that age and apolipoprotein E genotype should be taken into account when interpreting β biomarkers in PPA.

Neurodegenerative Diseases Dominantly Inherited Alzheimer Disease: Cognitive and Biomarker Changes

Dominantly Inherited Alzheimer Disease: Cognitive and Biomarker Changes

Investigators examined the onset, sequence, and rate of progression of biomarker and clinical measures across the spectrum of Alzheimer disease, using the Dominantly Inherited Alzheimer Network study.

Neurodegenerative Diseases PET Scans Distinguish Alzheimer Disease From Other Neurodegenerative Diseases

PET Scans Distinguish Alzheimer Disease From Other Neurodegenerative Diseases

The use of positron emission tomography was able to discriminate between Alzheimer disease and other neurodegenerative disorders in a multicenter, cross-sectional study conducted at 3 dementia centers in South Korea, Sweden, and the United States.

Neurodegenerative Diseases 18F-FDG PET Algorithm Allows Early Prediction of Alzheimer's

18F-FDG PET Algorithm Allows Early Prediction of Alzheimer's

Fluorine 18 fluorodeoxyglucose PET of the brain can be used to develop a deep learning algorithm for early prediction of AD that has high specificity and sensitivity.

Neurodegenerative Diseases Abnormalities in Genes Linked to IRSP in Alzheimer Disease

Abnormalities in Genes Linked to IRSP in Alzheimer Disease

Individuals with Alzheimer disease have abnormalities and reductions in gene expression in the parahippocampal gyri that map to genes associated with the insulin receptor signaling pathway.

Neurodegenerative Diseases Critical Illness and the Brain: Managing Risk for Cognitive Adverse Effects

Critical Illness and the Brain: Managing Risk for Cognitive Adverse Effects

The results highlight the importance of evaluating and monitoring cognitive function in individuals with recent critical illness or major infections, especially if they are already at risk for dementia.

Neurodegenerative Diseases Alzheimer Disease Biomarkers Expose Individuals to Long-Term Care Insurance Denial

Alzheimer Disease Biomarkers Expose Individuals to Long-Term Care Insurance Denial

Approximately 5.5 million Americans have Alzheimer disease or dementia.

Neurodegenerative Diseases Biomarkers of Alzheimer Disease Observed in Down Syndrome

Biomarkers of Alzheimer Disease Observed in Down Syndrome

Neurological and neuropsychological examinations were performed to assess intellectual disabilities, and biological assays were performed on collected CSF and plasma.

Neurodegenerative Diseases Multiple Births Associated With Greater Late-Life Risk for Alzheimer Disease

Multiple Births Associated With Greater Late-Life Risk for Alzheimer Disease

Grand multiparity was associated with significantly worse Mini-Mental State Examination scores compared with those with 1 to 4 completed pregnancies.

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