Lithium Compared With Newer Therapies as Adjunct to Antidepressants
The likelihood of help or harm, also known as the risk/benefit ratio, was found to be more favorable for lithium.
All articles by Cassandra Pardini, PharmD
Evidence to Support Suicidality Warning for Newer Antiseizure Meds Lacking
The analysis included 5 antiseizure medications (eslicarbazepine, perampanel, brivaracetam, cannabidiol, and cenobamate) evaluated in 17 randomized clinical trials.
ACE Inhibitors vs ARBs for First-Line Hypertension Treatment
Currently, ACE inhibitors and ARBs are both recommended as first-line therapies for the treatment of hypertension according to US and European guidelines.
Review of Acute Migraine Treatments Shows Many Effective, Opioids Not Appropriate
The aim of the study was to assess the benefits and risks associated with various acute treatments for episodic migraine.
Combination Treatment Appears Beneficial for Chronic Migraine
Data analysis revealed that CGRP mAbs were discontinued more frequently than onabotulinumtoxinA (23% vs 3%).
Timolol Eyedrops Evaluated for Acute Migraine Treatment
During the study, 50 migraine patients randomly received either topically applied timolol maleate ophthalmic solution, 0.5%, or placebo eyedrops.
Vaccination Linked to Reduced Alzheimer Disease Risk
At AAIC 2020, 2 presentations separately discussed observing a reduced risk of AD in patients who received the influenza and pneumonia vaccines.
Supplements With Undeclared Active Ingredients Pose Substantial Health Risk
A recent Morbidity and Mortality Weekly Report highlights the risks associated with use of over-the-counter products containing undeclared prescription ingredients as well as the importance of collaboration between various health departments and systems to ensure a prompt response to an outbreak.
Penicillin-, Ciprofloxacin-Resistant Meningococci Detected in United States
The CDC has reported observing a significant increase in the number of meningococcal disease cases with isolates containing a blaROB-1 β-lactamase enzyme gene, conferring resistance to penicillin antibiotics and, in some cases, ciprofloxacin as well.
Evidence Supporting Use of Compounded Topical Pain Creams Limited
Due to a lack of evidence on the safety of the ingredients used in topical pain cream, caution should be exercised when prescribing these preparations.
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