Acute Tubular Necrosis (ATN)
At a Glance Acute tubular necrosis (ATN) refers to acute kidney injury as a result of severe tubular damage. Ischemia and exposure to nephrotoxins are the primary causes of ATN. Ischemic damage is due to prolonged hypoperfusion characterized by inadequate glomerular filtration rate (GFR) and poor parenchymal cell function. Hypovolemia, septic shock, and major surgery…