Determining if a patient with subtle cognitive symptoms suffers from prodromal or preclinical Alzheimer disease (AD) and whether that patient will progress to AD dementia is a challenge. However, this determination is critically important in order to ascertain a correct and early diagnosis of AD. Researchers may have found one method that can help.
The goal of the researchers was to describe the short- and long-term effects of brexpiprazole on Positive and Negative Syndrome Scale (PANSS) “Marder factors.”
The researchers’ objective was to examine whether PTSD could be compared and assessed based on DSM-IV and DSM-5 criteria, using PTSD Checklists.
Using transcriptional profiling of mouse meningeal lymphatic endothelial cells, microglia and brain blood endothelial cells, the researchers showed that meningeal lymphatic function is coupled to microglia and brain vascular activation in Alzheimer disease.
Individuals with autism spectrum disorder often have issue with facial emotion recognition (FER). The researchers sought to determine whether these deficits arise because facial emotion information is not encoded in their neural signal, or because it is encoded, but fails to translate to FER behavior.
The researchers looked at the effectiveness of cognitive remediation on cognition and functioning in people diagnosed with schizophrenia.
While sleep dysregulation is a feature of dementia, it remains unclear whether the duration of sleep prior to old age is associated with dementia. The researchers examined the association between sleep duration and incidence of dementia using a 25-year follow-up.
The researchers tested whether antisocial personalities are associated with similar structural and neural alterations as those observed in criminal psychopathy.
With cannabis in the United States becoming more widely available for medical and recreational use, some with Parkinson disease (PD) are trying cannabis to control symptoms. However, not that much is currently known about the attitudes and experiences regarding cannabis use among those with PD.
With no conclusive preclinical diagnostic test for Parkinson disease, diagnosis is achieved primarily through observations by a physician of the decline in motor functions. And while studies of sebum are commonplace in dermatological conditions, sebum as a biofluid has rarely been used in disease diagnostics.
