Investigators installed GPS data loggers with custom software in participants’ vehicles to see if driving performance could predict preclinical Alzheimer disease.
Researchers investigated the associations of ADHD pharmacotherapy with externalizing symptoms and childhood suicidality.
Researchers examined the efficacy of cervical noninvasive vagus nerve stimulation as an adjunct to standard treatment for patients with Parkinson disease and freezing of gait.
The researchers compared the risks and benefits of reduced vs standard doses of antipsychotics for patients with schizophrenia.
Researchers studied how the length of the female reproductive period, which is an indicator of endogenous estrogen, is related to levels of cerebrospinal fluid biomarkers for Alzheimer disease.
Determining if a patient with subtle cognitive symptoms suffers from prodromal or preclinical Alzheimer disease (AD) and whether that patient will progress to AD dementia is a challenge. However, this determination is critically important in order to ascertain a correct and early diagnosis of AD. Researchers may have found one method that can help.
The goal of the researchers was to describe the short- and long-term effects of brexpiprazole on Positive and Negative Syndrome Scale (PANSS) “Marder factors.”
The researchers’ objective was to examine whether PTSD could be compared and assessed based on DSM-IV and DSM-5 criteria, using PTSD Checklists.
Using transcriptional profiling of mouse meningeal lymphatic endothelial cells, microglia and brain blood endothelial cells, the researchers showed that meningeal lymphatic function is coupled to microglia and brain vascular activation in Alzheimer disease.