Heather Johnson

With no conclusive preclinical diagnostic test for Parkinson disease, diagnosis is achieved primarily through observations by a physician of the decline in motor functions. And while studies of sebum are commonplace in dermatological conditions, sebum as a biofluid has rarely been used in disease diagnostics.

While treatment for mood stabilization in bipolar disorder is most commonly lithium, all patients do not respond to such treatment. The authors of this study investigated what causes lithium resistance.

This study explores the issue of suicidality in children and youth with epilepsy and psychiatric comorbidities.

This study looks at how the lack of awareness (anosognosia) of memory impairment evolves in the trajectory of Alzheimer disease.

Researchers performed a systematic review of PubMed literature until May
2020 including clinical sequencing studies that utilized next-generation sequencing (NGS) in individuals with epilepsy, autism spectrum disorder (ASD), or intellectual disability (ID).

Researchers looked to further connect the dots between cognitive behavioral therapy for insomnia and repetitive negative thinking.

Since the association between physiological sleep characteristics and brain structure is not well understood, researchers aimed to investigate gray matter volume and cognitive performance related to physiological sleep characteristics.

The comorbidity of depressive disorders and late-life neurodegenerative diseases including Alzheimer disease has been widely reported. This study looks into whether there is a causal relationship existing between both or, if their co-occurrence is due to confounding or common risk factors, such as aging.

After transplanting hESC-derived midbrain dopamine into the striatum of a PD model mouse, researchers found extensive graft integration with host circuitry.

This study examines whether pretreatment brain activation during cognitive control and reward processing is associated with treatment response to CBT in patients with OCD.

SSRI use after intracerebral hemorrhage may resolve depression symptoms, but also increases patients’ risk for recurrent stroke.

The use of cannabis in the past month among US adults with depression increased from 2005 to 2016.

In young adults, the use of electronic devices was found to contribute to insomnia symptoms more than mood disturbance, age, and biological sex.

Using phenotypic and genomic data from more than 100,000 participants, researchers systematically screened and validated a wide range of potential modifiable factors for depression.

A recent study aimed to assess the ability of classifiers to identify individuals with schizophrenia, autism spectrum disorder, and typical development based on findings from magnetic resonance imaging.

In a phase 3, double-blind trial, the effect of combined olanzapine and samidorphan treatment compared with treatment with olanzapine alone on the weight profile of patients with schizophrenia was evaluated.

A new randomized controlled clinical trial evaluated whether yoga and cognitive behavioral therapy are each more effective than stress education to treat generalized anxiety disorder.

Among participants living in a culturally diverse area of Greece, people with anxiety were more likely to experience loss of sleep or other sleep-related disorders.

The use of genetic evaluation for suicidal ideation may represent a future application for precision medicine.

The Lancet Commission added 3 new risk factors for dementia that coupled with the previous 9 lifestyle risk factors might prevent or delay up to 40% of dementias worldwide.