Broad Range of Drug-Drug Interactions in Migraine Prevention and Treatment
Researchers conducted a narrative review of the pharmacokinetics of major classes of migraine preventives and the implications of drug-drug interactions in treatment.
All articles by Jessica Nye, PhD
Targeted Therapy for Recurrent Seizure-Related GRIN1 Variant
This case study detailed a pediatric patient with drug-resistant seizures and early-onset epileptic encephalopathy who carried a GRIN1 variant.
Solriamfetol May Improve Sleep Latency Among Patients With Parkinson Disease
This phase 2, double-blind trial of solriamfetol evaluated the dose-dependent effects on sleep latency in patients with Parkinson disease.
Youth With Tourette Disorder-Associated Tic May Respond to Behavioral Therapy
Study researchers assessed the role of cognitive control processes in tic severity reduction, as well as treatment response to behavioral therapy in youth with Tourette disorder.
First Alzheimer Disease Prevention Trial Using Amyloid-Targeting Drugs Gantenerumab or Solanezumab
The researchers conducted a randomized, placebo-controlled, multi-arm trial of gantenerumab or solanezumab in participants with dominantly inherited Alzheimer disease across asymptomatic and symptomatic disease stages.
Chronic Insufficient Sleep Widespread Among Active-Duty Sailors in the US Navy
This cross-sectional study addressed potential targets to address chronic insufficient sleep in Navy sailors assigned to warships in the United States.
Trigeminal Neuralgia: A Rare Facial Pain Condition Comprising 3 Distinct Subtypes
Study researchers conducted a narrative review to update the public on the new classification of trigeminal neuralgia, clinical signs, pathophysiology, and management.
Many Effective Therapies for Acute Migraine Pain but Little Evidence Supports Use of Opioids
The researchers’ goal was to weigh the risks and benefits of acute treatments for episodic migraine in adults.
Prefrontal Cortical Thinning Associated With Increased Cannabis Use During Adolescence
Researchers examined the extent cannabis use is associated with magnetic resonance imaging–measured cerebral cortical thickness development during adolescence.
Variation in Neurologic Criteria Protocols for Pediatric Brain Death in the United States
To evaluate the variability in pediatric death by neurologic criteria (DNC) protocols, study investigators assessed US pediatric institutions and compared them to the 2011 DNC guidelines.
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