The investigators observed a statistically significant relapse rate among those discontinuing medication for ADHD, which remained significant in subgroup analyses of both age groups.
Excess mortality occurred as the result of a number of causes, including overdose, injuries, and both infectious and noncommunicable diseases.
Patients with bipolar disorder experienced significant reductions in sleep efficiency, which was not the case in patients with schizophrenia, although effect sizes for bipolar disorder were smaller overall.
The prevalence of autism spectrum disorder has been increasing over the past few decades and depending on the region, it is estimated to occur in 1% to 2% of children.
In patients with Huntington disease, higher levels of functional impairment and current alcohol consumption were significantly correlated with missing work in multivariate logistic regression analyses.
Depression contributed to elevated ratings in patients with MDD on items related to perceived inability to cope with the negative consequences of disturbed sleep and reported tendency to cancel social plans after poor sleep.
The results of the study point to the validity of the Research Domain Criteria initiative and suggest that neuroimaging findings may not be specific to certain psychiatric disorders.
After controlling for depression, irritability, and anxiety, the investigators found no direct effect of ADHD symptoms on suicidality.
Anna S. Urrila, MD and colleagues sought to explore whether sleep symptoms in adolescents with MDD were associated with long-term outcomes.
Behavioral variant frontotemporal dementia, a neurodegenerative disease that affects the frontal and anterior temporal lobes, results in disordered socioemotional behavior.
