Comparative Efficacy of Clopidogrel vs Prasugrel in Noncardioembolic Ischemic Stroke
A large phase 3 trial compared prasugrel (3.75 mg/day) with clopidogrel (75 mg/day) for secondary stroke prevention in patients with noncardioembolic stroke.
All articles by Sheila Jacobs
Few Patients Discharged From ED With Nonspecific Headache Are Readmitted With Serious Condition
Few patients who were discharged from the emergency department with a nonspecific diagnosis of headache or back pain were readmitted for a serious neurologic condition or died as inpatients within 30 days of the initial visit.
Witness Observations Valuable for the Diagnosis of Transient Loss of Consciousness
A comprehensive profile of witness-observable transient loss of consciousness manifestations can make an important contribution to differentiation between epilepsy, syncope, and psychogenic nonepileptic seizures.
Late Onset of Migraine With Aura Linked to Increased Stroke Risk in Late Life
The study underscores the importance of migraine with aura symptom onset in the evaluation of ischemic stroke risk in late life.
Managing Anxiety, Depression in Multiple Sclerosis Key to Mitigating Cognitive Effects of Disease
The management of symptoms of anxiety and of depression in patients with MS is key to mitigating their effect on cognition and functioning.
Functional, Emotional Impairments Likely Following Transient Ischemic Attack
Compared with the general population, people attending transient ischemic attack clinics have functional and emotional deficits.
Ketogenic Diet, Modified Atkins Plan Effectively Reduce Seizure Frequency in Refractory Epilepsy
The investigators sought to evaluate the efficacy and tolerability of the ketogenic diet and modified Atkins diet in pediatric patients with refractory epilepsy of genetic etiology.
Delays in ON Time Common Among Levodopa-Treated Patients
The most frequently reported symptoms while patients waited for ON-period included slowness, fatigue, reduced dexterity, difficulty in walking, and problems with balance.
Statins, NSAIDS Have No Apparent Survival Benefit for Grade IV Glioma
In certain parts of the analysis, the use of selective COX-2 inhibitors and metamizol was associated with inferior patient survival.
Electrode Placement in Subthalamic Nucleus May Restore Nonmotor Cognitive Functioning
Investigators examined whether subthalamic nucleus during the use of deep brain stimulation has an effect on risk-reward trade-off decisions, and evaluated its dependency on electrode placement.
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